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Volume 18
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10.21775/cimb.018.043
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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
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Review

Attomole-Level Genomics with Single-Molecule Direct DNA, cDNA and RNA Sequencing Technologies

by
Fatih Ozsolak
Helicos BioSciences Corporation Cambridge, MA, USA
Curr. Issues Mol. Biol. 2016, 18(1), 43-48; https://doi.org/10.21775/cimb.018.043
Submission received: 25 April 2015 / Revised: 10 June 2015 / Accepted: 25 June 2015 / Published: 8 July 2015
Versions Notes

Abstract

With the introduction of next-generation sequencing (NGS) technologies in 2005, the domination of microarrays in genomics quickly came to an end due to NGS's superior technical performance and cost advantages. By enabling genetic analysis capabilities that were not possible previously, NGS technologies have started to play an integral role in all areas of biomedical research. This chapter outlines the low-quantity DNA/cDNA sequencing capabilities and applications developed with the Helicos single molecule DNA sequencing technology.
Keywords: next-generation sequencing; (NG) technologies; microarrays; genomics; biomedical research; sequencing; DNA sequencing technology next-generation sequencing; (NG) technologies; microarrays; genomics; biomedical research; sequencing; DNA sequencing technology

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MDPI and ACS Style

Ozsolak, F. Attomole-Level Genomics with Single-Molecule Direct DNA, cDNA and RNA Sequencing Technologies. Curr. Issues Mol. Biol. 2016, 18, 43-48. https://doi.org/10.21775/cimb.018.043

AMA Style

Ozsolak F. Attomole-Level Genomics with Single-Molecule Direct DNA, cDNA and RNA Sequencing Technologies. Current Issues in Molecular Biology. 2016; 18(1):43-48. https://doi.org/10.21775/cimb.018.043

Chicago/Turabian Style

Ozsolak, Fatih. 2016. "Attomole-Level Genomics with Single-Molecule Direct DNA, cDNA and RNA Sequencing Technologies" Current Issues in Molecular Biology 18, no. 1: 43-48. https://doi.org/10.21775/cimb.018.043

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