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Volume 26
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10.21775/cimb.026.093
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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
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Article

Applications of CRISPR/Cas9 in Reproductive Biology

by
Faheem Ahmed Khan
,
Nuruliarizki Shinta Pandupuspitasari
,
Huang ChunJie
,
Hafiz Ishfaq Ahmad
,
Kai Wang
,
Muhammad Jamil Ahmad
and
ShuJun Zhang
*
Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of the Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2018, 26(1), 93-102; https://doi.org/10.21775/cimb.026.093
Submission received: 1 June 2017 / Revised: 3 July 2017 / Accepted: 5 August 2017 / Published: 7 September 2017

Abstract

Genome editing is unravelling its benefits in wide areas of scientific development and understanding. The advances of genome editing from ZFNs and TALLENs to CRISPRs defines its wide applicability. Reproduction is the fundamental process by which all organisms maintain their generations. CRISPR/Cas9, a new versatile genome editing tool has been recently tamed to correct several disease causing genetic mutations, spreading its arms to improve reproductive health. It not only edits harmful genetic mutations but is also applied to control the spread of parasitic diseases such as malaria by introducing selfish genetic elements, propagated through generations and population via reproduction. These applications led us to review the recent developments of CRISPRs use in reproductive biology.

Share and Cite

MDPI and ACS Style

Khan, F.A.; Pandupuspitasari, N.S.; ChunJie, H.; Ahmad, H.I.; Wang, K.; Ahmad, M.J.; Zhang, S. Applications of CRISPR/Cas9 in Reproductive Biology. Curr. Issues Mol. Biol. 2018, 26, 93-102. https://doi.org/10.21775/cimb.026.093

AMA Style

Khan FA, Pandupuspitasari NS, ChunJie H, Ahmad HI, Wang K, Ahmad MJ, Zhang S. Applications of CRISPR/Cas9 in Reproductive Biology. Current Issues in Molecular Biology. 2018; 26(1):93-102. https://doi.org/10.21775/cimb.026.093

Chicago/Turabian Style

Khan, Faheem Ahmed, Nuruliarizki Shinta Pandupuspitasari, Huang ChunJie, Hafiz Ishfaq Ahmad, Kai Wang, Muhammad Jamil Ahmad, and ShuJun Zhang. 2018. "Applications of CRISPR/Cas9 in Reproductive Biology" Current Issues in Molecular Biology 26, no. 1: 93-102. https://doi.org/10.21775/cimb.026.093

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