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Review

An Overview of Toxicogenomics

by
Hisham K. Hamadeh
,
Rupesh P. Amin
,
Richard S. Paules
and
Cynthia A. Afshari
*
National Institute of Environmental Health Sciences, Intramural Microarray Center, PO Box 12233, MD2-04, 111 Alexander Drive Bldg. 101, Research Triangle Park, NC 27709, USA
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2002, 4(2), 45-56; https://doi.org/10.21775/cimb.004.045
Submission received: 5 December 2001 / Revised: 4 January 2002 / Accepted: 7 February 2002 / Published: 5 April 2002

Abstract

Toxicogenomics is a rapidly developing discipline that promises to aid scientists in understanding the molecular and cellular effects of chemicals in biological systems. This field encompasses global assessment of biological effects using technologies such as DNA microarrays or high throughput NMR and protein expression analysis. This review provides an overview of advancing multiple approaches (genomic, proteomic, metabonomic) that may extend our understanding of toxicology and highlights the importance of coupling such approaches with classical toxicity studies.

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MDPI and ACS Style

Hamadeh, H.K.; Amin, R.P.; Paules, R.S.; Afshari, C.A. An Overview of Toxicogenomics. Curr. Issues Mol. Biol. 2002, 4, 45-56. https://doi.org/10.21775/cimb.004.045

AMA Style

Hamadeh HK, Amin RP, Paules RS, Afshari CA. An Overview of Toxicogenomics. Current Issues in Molecular Biology. 2002; 4(2):45-56. https://doi.org/10.21775/cimb.004.045

Chicago/Turabian Style

Hamadeh, Hisham K., Rupesh P. Amin, Richard S. Paules, and Cynthia A. Afshari. 2002. "An Overview of Toxicogenomics" Current Issues in Molecular Biology 4, no. 2: 45-56. https://doi.org/10.21775/cimb.004.045

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