Next Article in Journal
How Do Cancer-Related Mutations Affect the Oligomerisation State of the p53 Tetramerisation Domain?
Next Article in Special Issue
Hair Growth Effect of DN106212 in C57BL/6 Mouse and Its Network Pharmacological Mechanism of Action
Previous Article in Journal
Adenosine A2A Receptor Activation Regulates Niemann–Pick C1 Expression and Localization in Macrophages
Previous Article in Special Issue
Quercetin Alleviates Pulmonary Fibrosis in Silicotic Mice by Inhibiting Macrophage Transition and TGF-β-Smad2/3 Pathway
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
CIMB
Volume 45
Issue 6
10.3390/cimb45060316
cimb-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn

by
Kerem Canli
1,2,*,
Dilay Turu
3,
Atakan Benek
4,
Mustafa Eray Bozyel
1,
Özcan Simsek
5 and
Ergin Murat Altuner
6
1
Department of Biology, Faculty of Science, Dokuz Eylül University, Izmir 35390, Turkey
2
Fauna and Flora Research and Application Center, Dokuz Eylül University, Izmir 35390, Turkey
3
Department of Biology, Graduate School of Natural and Applied Science, Dokuz Eylül University, Izmir 35390, Turkey
4
Department of Biology, Graduate School of Natural and Applied Sciences, Kastamonu University, Kastamonu 37150, Turkey
5
Department of Forestry, Yenice Vocational School, Çanakkale Onsekiz Mart University, Çanakkale 17950, Turkey
6
Department of Biology, Faculty of Science, Kastamonu University, Kastamonu 37150, Turkey
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2023, 45(6), 4970-4984; https://doi.org/10.3390/cimb45060316
Submission received: 6 May 2023 / Revised: 1 June 2023 / Accepted: 4 June 2023 / Published: 7 June 2023
(This article belongs to the Collection Application of Natural and Pseudo Natural Products in Drug Discovery and Development)
Versions Notes

Abstract

In this study, the chemical composition and biological activity of Allium scorodoprasum subsp. jajlae (Vved.) Stearn were investigated for the first time, focusing on its antimicrobial, antioxidant, and antibiofilm properties. A GC-MS analysis was employed to evaluate the composition of its secondary metabolites, identifying linoleic acid, palmitic acid, and octadecanoic acid 2,3-dihydroxypropyl ester as the major compounds in ethanol extract. The antimicrobial activity of A. scorodoprasum subsp. jajlae was assessed against 26 strains, including standard, food isolate, clinical isolate, and multidrug-resistant ones, as well as three Candida species using the disc diffusion method and the determination of the minimum inhibitory concentration (MIC). The extract showed strong antimicrobial activity against Staphylococcus aureus strains, including methicillin-resistant and multidrug-resistant strains, as well as Candida tropicalis and Candida glabrata. Its antioxidant capacity was evaluated using the DPPH method, revealing a high level of antioxidant activity in the plant. Additionally, the antibiofilm activity of A. scorodoprasum subsp. jajlae was determined, demonstrating a reduction in biofilm formation for the Escherichia coli ATCC 25922 strain and an increase in biofilm formation for the other tested strains. The findings suggest potential applications of A. scorodoprasum subsp. jajlae in the development of novel antimicrobial, antioxidant, and antibiofilm agents.
Keywords: Allium scorodoprasum subsp. jajlae; antimicrobial activity; antioxidant activity; antibiofilm activity; GC-MS analysis Allium scorodoprasum subsp. jajlae; antimicrobial activity; antioxidant activity; antibiofilm activity; GC-MS analysis

Share and Cite

MDPI and ACS Style

Canli, K.; Turu, D.; Benek, A.; Bozyel, M.E.; Simsek, Ö.; Altuner, E.M. Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn. Curr. Issues Mol. Biol. 2023, 45, 4970-4984. https://doi.org/10.3390/cimb45060316

AMA Style

Canli K, Turu D, Benek A, Bozyel ME, Simsek Ö, Altuner EM. Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn. Current Issues in Molecular Biology. 2023; 45(6):4970-4984. https://doi.org/10.3390/cimb45060316

Chicago/Turabian Style

Canli, Kerem, Dilay Turu, Atakan Benek, Mustafa Eray Bozyel, Özcan Simsek, and Ergin Murat Altuner. 2023. "Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn" Current Issues in Molecular Biology 45, no. 6: 4970-4984. https://doi.org/10.3390/cimb45060316

APA Style

Canli, K., Turu, D., Benek, A., Bozyel, M. E., Simsek, Ö., & Altuner, E. M. (2023). Biochemical and Antioxidant Properties as well as Antimicrobial and Antibiofilm Activities of Allium scorodoprasum subsp. jajlae (Vved.) Stearn. Current Issues in Molecular Biology, 45(6), 4970-4984. https://doi.org/10.3390/cimb45060316

Article Metrics

Back to TopTop