Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model
Abstract
:1. Introduction
2. Results
2.1. Radical Scavenging Activity of Dieckol and PFF-A
2.2. ABR Threshold Shifts after Noise Exposure
2.3. Hair Cell Phalloidin Staining and Counts
3. Discussion
4. Materials and Methods
4.1. Preparation of PFF-A and Dieckol
4.2. 1,1-Diphenyl-2-picrylhydrazyl Assay
4.3. Noise Exposure
4.4. Auditory Brainstem Response Recordings
4.5. Outer Hair Cell Staining
4.6. Statistical Analyses
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Woo, H.; Kim, M.-K.; Park, S.; Han, S.-H.; Shin, H.-C.; Kim, B.-g.; Oh, S.-H.; Suh, M.-W.; Lee, J.-H.; Park, M.-K. Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model. Mar. Drugs 2021, 19, 443. https://doi.org/10.3390/md19080443
Woo H, Kim M-K, Park S, Han S-H, Shin H-C, Kim B-g, Oh S-H, Suh M-W, Lee J-H, Park M-K. Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model. Marine Drugs. 2021; 19(8):443. https://doi.org/10.3390/md19080443
Chicago/Turabian StyleWoo, Hyunjun, Min-Kyung Kim, Sohyeon Park, Seung-Hee Han, Hyeon-Cheol Shin, Byeong-gon Kim, Seung-Ha Oh, Myung-Whan Suh, Jun-Ho Lee, and Moo-Kyun Park. 2021. "Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model" Marine Drugs 19, no. 8: 443. https://doi.org/10.3390/md19080443