1-O-alkyl-glycerols from Squid Berryteuthis magister Reduce Inflammation and Modify Fatty Acid and Plasmalogen Metabolism in Asthma Associated with Obesity
Round 1
Reviewer 1 Report
This study of Yulia Denisenko revealed the protective effect of Marine-derived 1-O-alkyl-glycerols (AGs) Asthma Associated with Obesity. This study showed that ingestion of 0.8g daily ameliorate lung function, reduce inflammation, decrease leptin; and adiponectin generation…
My recommendations are:
1. The plagiarism rate is 27%, it must be reduced to 20%
2. The number of patients used is too few 19 patients?
3. It is necessary to add the number of experimentation ethic
4. Why the choice of the 0.8g/day dose? also the dose should be based on body weight
Comments for author File: Comments.pdf
Author Response
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Author Response File: Author Response.pdf
Reviewer 2 Report
This a well written paper that aimed to investigate the effect of AGs from squid Berryteuthis magister 15 on lung function, fatty acid and plasmalogen levels, cytokine and adipokine production in obese 16 patients with asthma
Figure C is not understandable, Please include the bar charts
Table 2. Please remove the column healthy, it counduses the analysis
dividing for categories and time is not appropriate. you can compare status and time in 2 different plots. Please apply this strategy
It is not fruitful looking diseases and time in the same x axis. It does not make sense at all.
Please discus
Author Response
Please see the attachment.
Author Response File: Author Response.docx