Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study
Abstract
:1. Introduction
2. Protocol Objectives
3. Methods
3.1. Study Patients
3.2. Phenotype Definition in Study Patients
3.3. Ethics Statements and Dissemination
3.4. Genotype Assays
3.5. Statistical Analysis
SNP ID | Alleles | Region | Localization |
---|---|---|---|
CRP gene | |||
rs1800947 | G/C | Coding exón | +1059 |
rs1130864 | C/T | 3′ UTR | +1444 |
rs2794521 | A/G | Promoter | −717 |
rs1205 | G/A | 3′ UTR | +3872 |
TNF-α gene | |||
rs361525 | G/A | Promoter | −238 |
rs1800629 | G/A | Promoter | −308 |
rs1799724 | C/T | Promoter | −857 |
rs1800630 | C/A | Promoter | −863 |
rs1799964 | T/C | Promoter | −1031 |
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Hernández-Díaz, Y.; Tovilla-Zárate, C.A.; Juárez-Rojop, I.; López-Narváez, M.L.; Álvarez-Cámara, J.F.; González-Castro, T.B. Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study. Int. J. Environ. Res. Public Health 2016, 13, 103. https://doi.org/10.3390/ijerph13010103
Hernández-Díaz Y, Tovilla-Zárate CA, Juárez-Rojop I, López-Narváez ML, Álvarez-Cámara JF, González-Castro TB. Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study. International Journal of Environmental Research and Public Health. 2016; 13(1):103. https://doi.org/10.3390/ijerph13010103
Chicago/Turabian StyleHernández-Díaz, Yazmín, Carlos Alfonso Tovilla-Zárate, Isela Juárez-Rojop, María Lilia López-Narváez, José Francisco Álvarez-Cámara, and Thelma Beatriz González-Castro. 2016. "Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study" International Journal of Environmental Research and Public Health 13, no. 1: 103. https://doi.org/10.3390/ijerph13010103