Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Laboratory Testing
2.3. Statistical Analysis
3. Results
3.1. Seroprevalence of Measles Antibody in Qian County
3.2. Demographic Characteristics of the Children
3.3. Predictors for Seroprevalence among Children
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
Abbreviations
IgG | Immunoglobulin G |
WHO | World Health Organization |
MMR | Measles, Mumps, and Rubella |
SIA | Supplementary Immunization Activity |
OR | Odds Ratio |
CI | Confidence Interval |
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Region | Sample Size | Seroprevalence of Measles Antibody n (%) |
---|---|---|
Dayang | 32 | 25 (78.13) |
Tiefo | 30 | 26 (86.67) |
Xuelu | 30 | 26 (86.67) |
Jiangcun | 31 | 27 (87.10) |
Xinyang | 31 | 27 (87.10) |
Linping | 31 | 27 (87.10) |
Wudian | 30 | 27 (90.00) |
Daqiang | 30 | 27 (90.00) |
Zhugan | 30 | 27 (90.00) |
Lingyuan | 31 | 28 (90.32) |
Malian | 29 | 27 (93.10) |
Fengyang | 30 | 28 (93.33) |
Changliu | 30 | 28 (93.33) |
Liangcun | 30 | 28 (93.33) |
Moxi | 30 | 28 (93.33) |
Yanghan | 30 | 28 (93.33) |
Zhoucheng | 30 | 28 (93.33) |
Wangcun | 30 | 28 (93.33) |
Shiniu | 30 | 28 (93.33) |
Yangyu | 30 | 28 (93.33) |
Qianling | 30 | 28 (93.33) |
Liangshan | 30 | 28 (93.33) |
Yanghong | 30 | 28 (93.33) |
Guantou | 30 | 29 (96.67) |
Chengguan | 30 | 29 (96.67) |
Total | 755 | 688 (91.13) |
Demographic Variables | Sample Size | Measles Antibody Seroprevalence n (%) | χ2 | p |
---|---|---|---|---|
Gender | ||||
Boy | 425 | 384 (90.4) | 0.718 | 0.397 |
Girl | 330 | 304 (92.1) | ||
Age | ||||
4 years | 247 | 242 (98.0) | 48.245 | <0.001 |
3 years | 251 | 237 (94.4) | ||
2 years | 257 | 209 (81.3) | ||
District type | ||||
Rural | 247 | 223 (90.3) | 1.942 | 0.379 |
Suburban | 124 | 110 (88.7) | ||
Urban | 384 | 355 (92.4) | ||
Mother’s education | ||||
Primary school | 190 | 165 (86.8) | 8.738 | 0.033 |
Middle school | 221 | 199 (90.0) | ||
High school | 208 | 195 (93.8) | ||
Vocational College/University or higher | 136 | 129 (94.9) | ||
Measles vaccine dose | ||||
1 | 24 | 5 (20.8) | 251.756 | <0.001 |
2 | 188 | 142 (75.5) | ||
3 | 543 | 541 (99.6) | ||
Maternal history of measles infection | ||||
Yes | 34 | 31 (91.2) | 0.648 | 0.723 |
No | 683 | 621 (90.9) | ||
Unknown | 38 | 36 (94.7) |
Variables | Crude OR | 95% CI | p | Adjusted OR | 95% CI | p | |
---|---|---|---|---|---|---|---|
Measles vaccine dose | 1 (reference) | - | |||||
2 | 11.7 | 4.1–33.2 | <0.001 | 11.3 | 4.0–32.2 | <0.001 | |
3 | 1027.9 | 187.3–5640.4 | <0.001 | 685.5 | 152.1–3089.1 | <0.001 | |
District type | Rural (ref) | - | |||||
Suburban | 0.8 | 0.4–1.7 | 0.637 | 0.9 | 0.7–1.3 | 0.713 | |
Urban | 1.3 | 0.7–2.3 | 0.339 | 1.1 | 0.8–1.3 | 0.341 | |
Mother’s education | Primary school (ref) | - | |||||
Middle school | 1.4 | 0.7–2.5 | 0.309 | 1.1 | 0.8–1.4 | 0.802 | |
High school | 2.3 | 1.1–4.6 | 0.019 | 2.2 | 1.4–6.9 | 0.006 | |
Vocational College/University or higher | 2.8 | 1.2–6.7 | 0.017 | 2.6 | 1.1–8.6 | 0.037 | |
Maternal history of measles disease | Yes (reference) | - | |||||
No | 1.0 | 0.3–3.3 | 0.960 | 0.8 | 0.3–2.7 | 0.923 | |
Unknown | 1.7 | 0.3–11.1 | 0.553 | 2.4 | 0.8–16.2 | 0.477 |
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Wang, X.; Ma, M.; Hui, Z.; Terry, P.D.; Zhang, Y.; Su, R.; Wang, M.; Gu, W.; Li, L. Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children. Int. J. Environ. Res. Public Health 2017, 14, 605. https://doi.org/10.3390/ijerph14060605
Wang X, Ma M, Hui Z, Terry PD, Zhang Y, Su R, Wang M, Gu W, Li L. Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children. International Journal of Environmental Research and Public Health. 2017; 14(6):605. https://doi.org/10.3390/ijerph14060605
Chicago/Turabian StyleWang, Xiaoqin, Mei Ma, Zhaozhao Hui, Paul D. Terry, Yue Zhang, Rui Su, Mingxu Wang, Wei Gu, and Ling Li. 2017. "Seroprevalence of Measles Antibodies and Predictors for Seropositivity among Chinese Children" International Journal of Environmental Research and Public Health 14, no. 6: 605. https://doi.org/10.3390/ijerph14060605