Definitions and Prevalence of Multimorbidity in Large Database Studies: A Scoping Review
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Study Characteristics
3.2. Prevalence of Multimorbidity
3.3. Definition of Multimorbidity
3.4. Diagnosis Codes and Algorithms Used
4. Discussion
4.1. Definitions of Multimorbidity
4.2. List of Conditions Used
4.3. Inclusion of Mental Health Conditions
4.4. Diagnosis Coding Systems and Algorithms Used
4.5. Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Article Number | Author, Year of Publication | Study Design | Country | Population Age | Population Type | Type of Database | Number of Conditions for MM Definition | Number of Chronic Conditions in List | Definition of Chronic Condition | Additional Means to Diagnose Conditions |
---|---|---|---|---|---|---|---|---|---|---|
1 | Arbelle et al., 2014 [37] | CS | Israel | ≥0 | General population | EMR | 2+ | 40 | No | a. Prescription data b. Hospital discharge codes c. Billing info |
2 | Barnett et al., 2012 [28] | CS | Scotland | ≥0 | Primary care | EMR | 2+ | 40 | Yes | Prescription data |
3 | Frolich et al., 2019 [20] | CS | Denmark | >16 | a. Primary care b. Secondary care | EMR | 2+ | 16 | No | a. Prescription data b. Healthcare service utilisation |
4 | Fu et al., 2014 [21] | CS | Taiwan | ≥0 | General population | Insurance database | 2+ | 15 | No | No |
5 | Lenzi et al., 2016 [22] | CS | Italy | ≥18 | General population | EMR | 2+ | 26 | No | Prescription data |
6 | Lochner et al., 2013 [23] | CS | U.S. | ≥0 | Insurance population | Insurance database | 2+ | 15 | No | No |
7 | Lochner. et al., 2013 [24] | CS | U.S. | ≥0 | Insurance population | Insurance database | 2+ | 15 | No | No |
8 | Low et al., 2019 [35] | CS | Singapore | ≥0 | a. Primary care b. Tertiary care c. Community hospitals | Government administrative data | 2+ | 48 | No | No |
9 | McLean et al., 2014 [25] | CS | Scotland | ≥25 | Primary care | EMR | 2+ | 40 | No | Prescription data |
10 | Mitsutake et al., 2019 [36] | CS | Japan | ≥75 | General population | Insurance database | 2+ & 3+ | 22 | No | No |
11 | Ornstein et al., 2013 [32] | CS | U.S. | ≥18 | Primary care | EMR | 2+ | 24 | No | No |
12 | Orueta et al., 2014 [29] | CS | Spain | ≥0 | General population | EMR | 2+ | 52 | No | Prescription data |
13 | Pefoyo et al., 2015 [33] | RC | Canada | 0–105 | General population | Insurance database | 2+ | 16 | No | No |
14 | Ryan et al., 2018 [18] | CS | Canada | 0–105 | General population | EMR | 3+ | 17 | No | Prescription data |
15 | Schiotz et al., 2017 [30] | CS | Denmark | ≥16 | General population | EMR | 2+ | 16 | No | a. Prescription data b. Healthcare service utilisation |
16 | Steinmann et al., 2012 [19] | RC | U.S. | ≥65 | Special group: Veterans | Government administrative data | DNS | 23 | No | No |
17 | Thavorn et al., 2017 [34] | RC | Canada | 0–105 | General population | EMR | 2+ | 16 | No | No |
18 | Violan et al., 2019 [26] | CS | Spain | ≥65–99 | Primary care | EMR | 2+ | 60 | No | a. Prescription data b. Other clinical parameters |
19 | Violan et al., 2013 [27] | CS | Spain | ≥15 | Primary care | EMR | 2+ | 27 | No | No |
20 | Violan et al., 2014 [31] | CS | Spain | ≥19 | a. Primary care b. Urban population | EMR | 2+ | 147 | No | No |
Category | Number of Articles in the Category | Arbelle, J. E., 2014 | Barnett, K., 2012 | Frolich, A., 2019 | Fu, Serena, 2014 | Lenzi, J., 2016 | Lochner, K. A., 2013 | Lochner, K. A., 2013 | Low, L.L., 2019 | McLean, G., 2014 | Mitsutake, S., 2019 | Ornstein, S. M., 2013 | Orueta, J. F., 2014 | Pefoyo, A. J., 2015 | Ryan, B. L., 2018 | Schiotz, M. L., 2017 | Steinmann, M. A., 2012 | Thavorn, K., 2017 | Violan, C., 2019 | Violan, C., 2013 | Violan, C., 2014 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. Cardiovascular | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
2. Endocrine | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
3. Mental health | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
4. Musculoskeletal | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
5. Neurology | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
6. Respiratory | 20 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
7. Neoplasia | 19 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
8. Rheumatology | 15 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||
9. Urology/renal | 15 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||
10. Gastrointestinal | 14 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||||||
11. Vascular | 11 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||
12. Hepatopancreaticobiliary | 10 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||||||||||
13. Infectious diseases (communicable) | 9 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||||
14. Ophthalmology | 9 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||||
15. Dermatology | 8 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||||||||||||
16. Disability | 7 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||||||
17. Ear Nose and Throat | 6 | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||||||||
18. Hematology | 6 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||||||||||||||
19. Immunologic | 5 | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||||||||||
20. Genetic | 2 | ✓ | ✓ | ||||||||||||||||||
21. Others | 2 | ✓ | ✓ |
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Chua, Y.P.; Xie, Y.; Lee, P.S.S.; Lee, E.S. Definitions and Prevalence of Multimorbidity in Large Database Studies: A Scoping Review. Int. J. Environ. Res. Public Health 2021, 18, 1673. https://doi.org/10.3390/ijerph18041673
Chua YP, Xie Y, Lee PSS, Lee ES. Definitions and Prevalence of Multimorbidity in Large Database Studies: A Scoping Review. International Journal of Environmental Research and Public Health. 2021; 18(4):1673. https://doi.org/10.3390/ijerph18041673
Chicago/Turabian StyleChua, Ying Pin, Ying Xie, Poay Sian Sabrina Lee, and Eng Sing Lee. 2021. "Definitions and Prevalence of Multimorbidity in Large Database Studies: A Scoping Review" International Journal of Environmental Research and Public Health 18, no. 4: 1673. https://doi.org/10.3390/ijerph18041673