Hemoglobin A1c Levels Associated with Age and Gender in Taiwanese Adults without Prior Diagnosis with Diabetes
Abstract
:1. Introduction
2. Methods
2.1. Ethics Statement
2.2. Study Participants
2.3. Statistical Analysis
3. Results
3.1. Characteristics of Participants
3.2. HbA1c Associated with Age
3.3. HbA1c Levels between Sexes among Different Age Groups
3.4. HbA1c between Sexes for Different Hba1c Levels
3.5. HbA1c Associated with Age for Different Hba1c Level Groups
3.6. HbA1c Levels between Sexes for Different Hba1c Level Groups
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | β | SE | t-Value | p-Value |
---|---|---|---|---|
Age | 0.01401 | 0.00081 | 17.25 | <0.0001 |
Male (ref: Female) | 0.08301 | 0.01725 | 4.81 | <0.0001 |
Age Group | β | SE | t-Value | p-Value |
---|---|---|---|---|
Male | ||||
All age | 0.01082 | 0.00127 | 8.54 | <0.0001 |
Age: 30–49 | 0.01246 | 0.00341 | 3.66 | 0.0003 |
Age: 50–70 | 0.00331 | 0.00359 | 0.92 | 0.3567 |
Female | ||||
All age | 0.01713 | 0.00103 | 16.62 | <0.0001 |
Age: 30–49 | 0.01954 | 0.00236 | 8.27 | <0.0001 |
Age: 50–70 | 0.01295 | 0.00312 | 4.15 | <0.0001 |
Age Group | All | Male | Female | p-Value $ | |||
---|---|---|---|---|---|---|---|
N | Mean ± SD | n | Mean ± SD | n | Mean ± SD | ||
30–39 | 1070 | 5.47 ± 0.47 a | 517 | 5.55 ± 0.54 a | 553 | 5.40 ± 0.37 a | <0.0001 |
40–49 | 1316 | 5.63 ± 0.63 b | 583 | 5.69 ± 0.72 b | 733 | 5.58 ± 0.56 b | 0.0017 |
50–59 | 1429 | 5.80 ± 0.63 c | 632 | 5.83 ± 0.63 c | 797 | 5.77 ± 0.63 c | 0.0895 |
60–70 | 933 | 5.86 ± 0.61 d | 451 | 5.87 ± 0.70 c | 482 | 5.86 ± 0.51 d | 0.7522 |
p-value & | <0.0001 | <0.0001 | <0.0001 |
Group | All | HbA1c < 6.5% | HbA1c ≥ 6.5% | |||
---|---|---|---|---|---|---|
n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | |
Male | 2183 | 5.73 ± 0.66 | 2050 | 5.62 ± 0.32 | 133 | 7.54 ± 1.44 |
Female | 2565 | 5.65 ± 0.57 | 2449 | 5.57 ± 0.34 | 116 | 7.34 ± 1.29 |
p-value | <0.0001 | <0.0001 | 0.2504 |
Variable | β | SE | t-Value | p-Value |
---|---|---|---|---|
HbA1c < 6.5% for male | ||||
All age | 0.00757 | 0.00063 | 12.06 | <0.0001 |
Age: 30–49 | 0.00782 | 0.00167 | 4.68 | <0.0001 |
Age: 50–70 | 0.00253 | 0.00179 | 1.41 | 0.1583 |
HbA1c < 6.5% for female | ||||
All age | 0.01413 | 0.00060 | 23.46 | <0.0001 |
Age: 30–49 | 0.01386 | 0.00148 | 9.38 | <0.0001 |
Age: 50–70 | 0.01017 | 0.00175 | 5.82 | <0.0001 |
HbA1c ≥ 6.5% for male | ||||
All age | −0.03160 | 0.01336 | −2.36 | 0.0195 |
Age: 30–49 | −0.03960 | 0.06165 | −0.64 | 0.5248 |
Age: 50–70 | −0.00945 | 0.02301 | −0.41 | 0.6822 |
HbA1c ≥ 6.5% for female | ||||
All age | −0.01446 | 0.01379 | −1.05 | 0.2968 |
Age: 30–49 | −0.03813 | 0.04610 | −0.83 | 0.414 |
Age: 50–70 | −0.01529 | 0.02623 | −0.58 | 0.5616 |
Age Group | All | Male | Female | p-Value $ | |||
---|---|---|---|---|---|---|---|
n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | ||
HbA1c < 6.5% | |||||||
30–39 | 1051 | 5.42 ± 0.30 a | 506 | 5.49 ± 0.30 a | 545 | 5.37 ± 0.28 a | <0.0001 |
40–49 | 1262 | 5.54 ± 0.32 b | 557 | 5.59 ± 0.31 b | 705 | 5.50 ± 0.31 b | <0.0001 |
50–59 | 1330 | 5.68 ± 0.31 c | 578 | 5.69 ± 0.31 c | 752 | 5.69 ± 0.32 c | 0.4125 |
60–70 | 856 | 5.74 ± 0.32 d | 409 | 5.71 ± 0.33 c | 447 | 5.76 ± 0.32 d | 0.0448 |
p-value & | <0.0001 | <0.0001 | <0.0001 | ||||
HbA1c ≥ 6.5% | |||||||
30–39 | 19 | 7.72 ± 1.51 | 11 | 8.07 ± 1.77 | 8 | 7.24 ± 0.98 | 0.2456 |
40–49 | 54 | 7.74 ± 1.69 | 26 | 7.98 ± 2.01 | 28 | 7.51 ± 1.33 | 0.3167 |
50–59 | 99 | 7.41 ± 1.29 | 54 | 7.37 ± 1.04 | 45 | 7.46 ± 1.55 | 0.7407 |
60–70 | 77 | 7.23 ± 1.15 | 42 | 7.35 ± 1.33 | 35 | 7.07 ± 0.88 | 0.2754 |
p-value & | 0.153 | 0.145 | 0.487 |
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Huang, S.-H.; Huang, P.-J.; Li, J.-Y.; Su, Y.-D.; Lu, C.-C.; Shih, C.-L. Hemoglobin A1c Levels Associated with Age and Gender in Taiwanese Adults without Prior Diagnosis with Diabetes. Int. J. Environ. Res. Public Health 2021, 18, 3390. https://doi.org/10.3390/ijerph18073390
Huang S-H, Huang P-J, Li J-Y, Su Y-D, Lu C-C, Shih C-L. Hemoglobin A1c Levels Associated with Age and Gender in Taiwanese Adults without Prior Diagnosis with Diabetes. International Journal of Environmental Research and Public Health. 2021; 18(7):3390. https://doi.org/10.3390/ijerph18073390
Chicago/Turabian StyleHuang, Shih-Hao, Peng-Ju Huang, Jhong-You Li, Yu-De Su, Cheng-Chang Lu, and Chia-Lung Shih. 2021. "Hemoglobin A1c Levels Associated with Age and Gender in Taiwanese Adults without Prior Diagnosis with Diabetes" International Journal of Environmental Research and Public Health 18, no. 7: 3390. https://doi.org/10.3390/ijerph18073390