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Peer-Review Record

Psychopathological Impact in Patients with History of Rheumatic Fever with or without Sydenham’s Chorea: A Multicenter Prospective Study

Int. J. Environ. Res. Public Health 2022, 19(17), 10586; https://doi.org/10.3390/ijerph191710586
by Alessandro Orsini 1, Thomas Foiadelli 2, Attilio Sica 1,*, Andrea Santangelo 1, Niccolò Carli 1, Alice Bonuccelli 1, Rita Consolini 1, Sofia D’Elios 1, Nicolò Loddo 2, Alberto Verrotti 3, Giuseppe Di Cara 3, Chiara Marra 4, Maria Califano 4, Anna Fetta 4, Marianna Fabi 4, Stefania Bergamoni 5, Aglaia Vignoli 5,6, Roberta Battini 7,8, Marta Mosca 7, Chiara Baldini 7, Nadia Assanta 9, Pietro Marchese 9, Gabriele Simonini 10, Edoardo Marrani 10, Francesca Felicia Operto 11, Grazia Maria Giovanna Pastorino 11, Salvatore Savasta 12, Giuseppe Santangelo 13, Virginia Pedrinelli 7, Gabriele Massimetti 7, Liliana Dell’Osso 7, Diego Peroni 1, Duccio Maria Cordelli 4, Martina Corsi 14 and Claudia Carmassi 7add Show full author list remove Hide full author list
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Environ. Res. Public Health 2022, 19(17), 10586; https://doi.org/10.3390/ijerph191710586
Submission received: 27 July 2022 / Revised: 20 August 2022 / Accepted: 21 August 2022 / Published: 25 August 2022

Round 1

Reviewer 1 Report

Orsini et al.  presented a Italian multicenter prospective study on 48 patients with a previous diagnosis of acute rheumatic fever (ARF), with and without Sydenham’s chorea (SC), in order to assess the presence of neuropsychiatric symptoms after years of the onset of SC. The authors used eight different neuropsychological tests in each group (with and without SC).

They demonstrated  the presence of neuropsychiatric symptoms in the SC population with statistically significant results.

The work was conducted with good methodology and has adequate references. A significant population was studied and the psychopathological impact of SC was demonstrated even after years of its onset.

 

Tips:

-Line 450: Insert references

 

-Insert a short table with the neuropsychiatric symptoms detected (rf: lines 195-205)

 

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Reviewer 2 Report


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