Sedentary Behavior and Lower-Extremity Physical Function across the Lifespan of Adults with Multiple Sclerosis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Procedures
2.3. Measures
2.3.1. Demographic and Clinical Characteristics
2.3.2. Sedentary Behavior
2.3.3. Physical Function
2.4. Data Analysis
3. Results
3.1. Sample Characteristics
3.2. Descriptive Statistics for Sedentary Behavior and Physical Function
3.3. Bivariate Correlations between Sedentary Behavior and Physical Function
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristic | Overall (N = 216) | 20–39 Years (N = 59) | 40–59 Years (N = 93) | 60–79 Years (N = 64) | p-Value |
---|---|---|---|---|---|
Age (years [SD]) | 49.6 (13.3) | 32.9 (4.7) | 49.3 (5.6) | 65.5 (4.4) | <0.001 |
Sex (N, %) | 0.882 | ||||
Female | 163, 76% | 45, 76% | 69, 74% | 49, 77% | |
Male | 52, 24% | 13, 22% | 24, 26% | 15, 23% | |
Race (N, %) | 0.001 | ||||
Caucasian | 140, 65% | 27, 46% | 59, 63% | 54, 84% | |
Black/African American | 67, 31% | 26, 44% | 31, 33% | 10, 16% | |
Other | 8, 4% | 5, 9% | 3, 3% | 0, 0% | |
MS Type (N, %) | 0.184 | ||||
Relapsing remitting | 190, 88% | 52, 88% | 85, 91% | 53, 83% | |
Progressive | 19, 9% | 3, 5% | 7, 8% | 9, 14% | |
Unknown | 7, 3% | 4, 7% | 1, 1% | 2, 3% | |
Disease Duration (years [SD]) | 13.0 (9.6) | 5.8 (4.9) | 12.0 (7.5) | 21.2 (9.5) | <0.001 |
PDDS score (0–8) | 1 (3) | 1 (3) | 1 (3) | 3 (3.5) | 0.084 |
Variable | Overall (N = 211) | 20–39 Years (N = 57) | 40–59 Years (N = 91) | 60–79 Years (N = 63) | p-Value |
---|---|---|---|---|---|
Sedentary Behavior | |||||
Total sedentary time/day (min) | 497.7 (91.8) | 490.9 (103.4) | 507.4 (85.2) | 489.7 (90.3) | 0.449 |
Average number of breaks in sedentary time per day (N) | 5.5 (2.0) | 5.2 (2.3) | 5.8 (1.9) | 5.5 (1.8) | 0.236 |
Average sedentary bout length (min) | 44.2 (7.4) | 41.8 (8.5) | 44.5 (7.0) | 46.0 (6.6) | 0.013 |
Number of long sedentary bouts (N) | 4.8 (2.0) | 4.5 (2.3) | 5.1 (1.9) | 4.7 (1.9) | 0.287 |
Average total time spent in long sedentary bouts per day (min) | 222.8 (108.7) | 200.4 (109.1) | 230.8 (103.3) | 230.9 (115.0) | 0.238 |
SPPB | |||||
Summary (0–12) | 10.3 (2.4) | 11.1 (2.1) | 10.4 (2.3) | 9.5 (2.8) | 0.002 |
Balance (0–4) | 3.4 (1.0) | 3.7 (0.8) | 3.5 (1.0) | 3.1 (1.0) | 0.006 |
Gait (0–4) | 3.6 (0.9) | 3.7 (0.8) | 3.6 (0.8) | 3.4 (1.1) | 0.077 |
Strength (0–4) | 3.3 (1.2) | 3.7 (0.8) | 3.3 (1.1) | 3.0 (1.4) | 0.005 |
Variable | Overall (N = 202) | |||
---|---|---|---|---|
Summary | Balance | Gait | Strength | |
Total sedentary time/day (min) | −0.076 | −0.036 | −0.028 | −0.092 |
Average number of breaks in sedentary time per day (N) | −0.190 * | −0.078 | −0.105 | −0.193 ** |
Average sedentary bout length (min) | −0.312 ** | −0.244 ** | −0.169 * | −0.234 ** |
Number of long sedentary bouts (N) | −0.197 ** | −0.109 | −0.109 | −0.183 * |
Average total time spent in long sedentary bouts per day (min) | −0.210 ** | −0.112 | −0.099 | −0.193 ** |
Variable | 20–39 Years (N = 51) | 40–59 Years (N = 88) | 60–79 Years (N = 63) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | Balance | Gait | Strength | Summary | Balance | Gait | Strength | Summary | Balance | Gait | Strength | |
Total sedentary time/day (min) | −0.289 | −0.240 | −0.172 | −0.242 | 0.020 | −0.065 | 0.081 | 0.091 | −0.128 | 0.054 | −0.111 | −0.249 |
Average number of breaks in sedentary time per day (N) | −0.350 * | −0.245 | −0.187 | −0.281 | −0.080 | −0.045 | −0.028 | −0.059 | −0.274 * | −0.009 | −0.190 | −0.342 * |
Average sedentary bout length (min) | −0.354 * | −0.229 | −0.075 | −0.149 | −0.252 * | −0.249 * | −0.087 | −0.172 | −0.330 * | −0.133 | −0.349 ** | −0.325 * |
Number of long sedentary bouts (N) | −0.276 | −0.212 | −0.113 | −0.196 | −0.089 | −0.070 | −0.035 | −0.061 | −0.346 * | −0.094 | −0.259 | −0.370 ** |
Average total time spent in long sedentary bouts per day | −0.351 * | −0.242 | −0.123 | −0.207 | −0.096 | −0.084 | −0.012 | −0.059 | −0.284 * | −0.045 | −0.205 | −0.330 * |
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Jeng, B.; Šilić, P.; Huynh, T.L.T.; Motl, R.W. Sedentary Behavior and Lower-Extremity Physical Function across the Lifespan of Adults with Multiple Sclerosis. Int. J. Environ. Res. Public Health 2022, 19, 12466. https://doi.org/10.3390/ijerph191912466
Jeng B, Šilić P, Huynh TLT, Motl RW. Sedentary Behavior and Lower-Extremity Physical Function across the Lifespan of Adults with Multiple Sclerosis. International Journal of Environmental Research and Public Health. 2022; 19(19):12466. https://doi.org/10.3390/ijerph191912466
Chicago/Turabian StyleJeng, Brenda, Petra Šilić, Trinh L. T. Huynh, and Robert W. Motl. 2022. "Sedentary Behavior and Lower-Extremity Physical Function across the Lifespan of Adults with Multiple Sclerosis" International Journal of Environmental Research and Public Health 19, no. 19: 12466. https://doi.org/10.3390/ijerph191912466