Next Article in Journal
Data-Enhancement Strategies in Weather-Related Health Studies
Previous Article in Journal
Sleep Deprivation, Immune Suppression and SARS-CoV-2 Infection
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

A Comparison of Self-Referral and Referral via Primary Care Providers, through Two Similar Digital Mental Health Services in Western Australia

1
MindSpot and PORTS Clinics, MQ Health, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney 2109, Australia
2
WA Primary Health Alliance, Psychiatry, Medical School, University of Western Australia, Perth 6907, Australia
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2022, 19(2), 905; https://doi.org/10.3390/ijerph19020905
Submission received: 28 November 2021 / Revised: 12 January 2022 / Accepted: 13 January 2022 / Published: 14 January 2022

Abstract

:
Digital mental health services (DMHSs) deliver mental health information, assessment, and treatment, via the internet, telephone, or other digital channels. The current study compares two DMHSs operating in Western Australia (WA)—The Practitioner Online Referral System (PORTS) and MindSpot. Both provide telephone and online psychological services at no cost to patients or referrers. However, PORTS is accessed by patients via referral from health practitioners, and is designed to reach those who are financially, geographically, or otherwise disadvantaged. In contrast, MindSpot services are available to all Australian residents and patients can self-refer. This observational study compares characteristics and treatment outcomes for patients of PORTS and MindSpot in WA. Eligible patients were people who resided in WA and registered with either clinic from January 2019 to December 2020. Results showed that PORTS patients were more likely to be older, male, and unemployed. They were less likely to report a tertiary education and were more likely to live in areas with higher levels of socioeconomic disadvantage. Despite these differences, treatment outcomes were excellent for patients from both clinics. Results provide further evidence for the accessibility, acceptability, and effectiveness of DMHSs regardless of referral pathway or patient characteristics.

1. Introduction

Mental health disorders such as anxiety and depression are significant public health issues worldwide [1,2] and can be exacerbated by barriers to care such as cost, stigma, and limited availability of services [3]. This is particularly true in the current climate, with many traditional health care providers ceasing or reducing face-to-face service delivery because of COVID-19 pandemic restrictions [4,5]. Encouragingly, many randomized controlled trials (RCTs) and meta-analyses have shown that therapist-guided digital mental health services (DMHSs) are effective and acceptable to patients [6,7,8,9,10,11]. Despite the strong evidence base, attempts to integrate DMHSs into primary care systems around the world have met with varying success [12,13], indicating that there remain significant challenges related to service model design, implementation, and regulation. For example, a US-based study observed that the mismatch between traditional and digital health services in the “day-to-day” workflows for staff is a major challenge to successful implementation, requiring specialized and discrete strategies to align traditional and digital services [14]. In a European study extending across six countries (Belgium, France, Germany, Ireland, the Netherlands, and the United Kingdom), gaps in legal and regulatory frameworks were commonly found to limit the wider use of DMHSs [15]. In Sweden, despite national guidelines recommending the use of internet-administered cognitive behavior therapy (CBT) in primary care, less than 21% of surveyed health care centers had implemented it [16]. Similarly in Canada, internet-based CBT is largely unavailable in routine care, despite a brief issued by the Mental Health Commission of Canada in 2014 encouraging the broader use of technology in mental health care [17].
In Australia, the role of primary care in the provision of mental health services is well-recognized [18], as is the utility of integrating DMHSs into primary care frameworks. The Australian Government has funded and encouraged the uptake of DMHSs for several years, and recently committed to increasing funding for the sector [19]. It was one of the first federal governments to adopt an e-Mental Health Strategy [20], and to introduce national safety and quality standards [21]. However, consistent with experiences in other countries, little is known about the factors that ensure the safe, effective, and sustainable integration of DMHSs into the Australian primary health care system [22]. In 2015, the Australian Government recommended a stepped-care model for primary mental health care as a priority area for reform, and Primary Health Networks were established to improve the efficiency and effectiveness of medical services for patients, particularly those at risk of poor health outcomes [23]. In the state of Western Australia (WA), the WA Primary Health Alliance operates the three Western Australian Primary Health Networks (Perth North, Perth South, and Country WA), and in 2017 commissioned the Practitioner Online Referral and Treatment Service (PORTS; www.ports.org.au, accessed on 13 January 2022), a state-wide DMHS for residents of WA aged over 16 years. The PORTS service model was co-designed by the developers of the MindSpot Clinic (www.mindspot.org.au, accessed on 13 January 2022), a national DMHS that provides mental health services to Australian residents aged 18 years and over, funded by the Australian Government.
MindSpot and PORTS provide similar assessment and treatment options, and both are publicly funded and therefore free to patients. However, PORTS is accessed by patients only via direct referral from a primary health care provider and is designed to provide support to people that are traditionally considered hard-to-reach due to financial, geographical, or another disadvantage. In contrast, MindSpot services are not restricted to specific cohorts, and patients do not require a referral to access services. This provides a unique opportunity to test whether DMHSs can successfully target different patient cohorts via different referral pathways [24,25]. Specifically, this paper compares two DMHSs operating in Western Australia between 1 January 2019 to 31 December 2020. The paper aims to (1) provide a descriptive analysis and comparison of patient demographics and characteristics, and (2) compare treatment outcomes for patients who are referred by a health practitioner (PORTS) versus patients who self-refer (MindSpot).

2. Materials and Methods

2.1. Study Design and Participants

This study was designed as an observational cohort study according to STROBE guidelines [26]. It includes all eligible patients from both clinics who gave consent for their de-identified data to be analyzed for research purposes and who were referred between 1 January 2019 and 31 December 2020. Data from patients accessing MindSpot within this timeframe have been previously used to describe mental health treatment utilization in relation to the COVID-19 pandemic [5,27,28]. Approval to conduct the study was obtained from the Human Research Ethics Committee at Macquarie University (5201200912).

2.1.1. PORTS Patients

People are eligible for PORTS if they are a resident of WA, aged 16 years or older, and are facing disadvantages. Individuals are referred to PORTS by their General Practitioner (GP) or by an approved health practitioner. People are ineligible if they require urgent support, for example, because of imminent suicidal intent or acute psychosis. People requiring immediate or high-intensity support are triaged and on-referred to a more appropriate service, such as an acute crisis service high intensity service.

2.1.2. MindSpot Patients

People seeking assessment or treatment at MindSpot can access the service directly via the website or be referred by a health professional. Approximately 98% of people who register with MindSpot self-refer, although approximately 17% state that they were told about MindSpot by a health professional. MindSpot is a national service that can be accessed by Australian residents from all states and territories, but for the purposes of comparison, only patients who reported a WA postcode were included in the current study. People are eligible for MindSpot if they are 18 years or over, and an Australian resident eligible for publicly funded health services.

2.2. Clinical Models

PORTS and MindSpot are funded by the Western Australian Public Health Alliance and the Australian Department of Health respectively, and services are provided free of charge to patients and referrers. Both models were developed in collaboration with consumers, referrers, and researchers, according to the requirements of the funding agencies. Both clinics operate within comprehensive internal and external frameworks that align with Australian National Quality and Health Service Standards [21].

2.2.1. PORTS Clinical Model

In the metro Primary Health Networks (Perth North and Perth South), PORTS accepts GP referrals directly. Metro patients who complete an assessment are contacted by therapists by telephone to discuss assessment and treatment options. This discussion averages 25 min of therapist time and provides an opportunity to discuss a patient’s concerns in greater detail and allows therapists to tailor their advice and recommendations. Metro patients who then select to engage in treatment can choose to enroll in online or telephone-based treatment at PORTS, or they may be referred to a face-to-face psychological service. For patients located in the Country Primary Health Network, which includes the entire state of WA bar metropolitan Perth, PORTS service options are similar, but referral pathways are tailored to the needs of each region of Country WA. For example, PORTS may more directly support mental health services in Country WA during periods of high service demand or health practitioner workforce shortages [25].
PORTS delivers online psychological treatment courses or brief CBT and strengths-based telephone therapy. Both are based on principles of CBT and are delivered by mental health professionals, primarily registered psychologists, who have received training in the delivery of digital mental health services. Other clinical staff are available to therapists for consultation, supervision, and training, including a cultural advisor, an Indigenous advisor, and a psychiatrist.

2.2.2. MindSpot Clinical Model

The MindSpot clinic can be accessed directly via the website (www.mindspot.org.au, accessed on 13 January 2022), which provides information about anxiety and depression, and management of symptoms. People seeking assessment or treatment with MindSpot register by creating an account and completing relevant questionnaires, online or over the phone. People who complete an assessment are invited to discuss their results and treatment options with a therapist. An assessment report that identifies clinically significant symptoms and includes information about how to access mental health or other services, is sent to each patient and, if requested, to a nominated health professional, usually a GP. Patients can also be referred and registered with MindSpot directly by their GP or another health professional. MindSpot therapists are registered mental health professionals, and psychiatrists and cultural consultants are available for consultation.

2.3. The Wellbeing Course

The Wellbeing Course is an online transdiagnostic intervention targeting symptoms of both anxiety and depression. The efficacy and acceptability of the course was initially established in a series of RCTs conducted by the eCentreClinic, a Macquarie University online research clinic [7,8,9,11]. Participants in the RCTs showed large clinical improvements in symptoms of depression, generalized anxiety disorder, social anxiety disorder, and panic disorder, with clinical improvements found to be sustained at two-year follow-up. The course is now used as part of routine care at both PORTS and the MindSpot Clinic, and several published reports have demonstrated the effectiveness and acceptability of the course in these real-world settings [5,29,30,31].
In the current study, the Wellbeing Course consisted of five lessons delivered to patients as a series of slides accessible at intervals over eight weeks. The content was designed to teach practical psychological skills and provide relevant psychoeducation.

2.4. Questionnaires and Measures

Demographic information was supplied by the referring health professional or the patient at the time of assessment. Postcodes were used to estimate socio-economic disadvantage using the Australian Bureau of Statistics Index of Relative Socio-economic Disadvantage (IRSD) [32]. Patients also answered questions about suicidal ideation, plans, and intent [33]. Standardized and validated self-report questionnaires and semi-structured interviews were used to identify the presence, severity, and duration of symptoms of specific anxiety disorders, depression, and psychological distress, and these were administered at assessment and throughout treatment. For the purposes of this study, treatment outcomes on the Kessler 10-Item Plus Scale (K-10+), the Patient Health Questionnaire 2-Item (PHQ-2), and the Generalized Anxiety Disorder 2-Item Scale (GAD-2) were analyzed. Patients were also asked about their satisfaction with treatment.
The K-10+ was administered at assessment and weekly throughout treatment, including the final week (post-treatment) and three months after treatment (follow-up). The first ten items comprise the K-10 scale, with scores ranging from 10 to 50, with higher scores indicating increasing levels of general psychological distress [34]. The K-10+ also includes four additional items intended to measure the functional impact of reported symptoms. In the current study, the item enquiring about the number of days out of role in the last month was analyzed.
The PHQ-2 is a two-item scale used to assess symptoms of depression [35]. Total scores on the PHQ-2 range from 0 to 6, with scores ≥3 indicative of a depressive disorder [35,36,37]. The GAD-2 is also a two-item scale, with a range from 0 to 6, and a score ≥3 indicating an anxiety disorder [35,36,37,38]. The PHQ-2 and GAD-2 were administered at assessment and throughout treatment, including post-treatment and follow-up, during the Wellbeing Course.

2.5. Statistical Analyses

Descriptive analyses and comparison of patient characteristics by clinic were performed. Chi-square analyses of linear-by-linear associations were used to test significance of categorical variables, and ANOVA was used to test significance of continuous variables. Generalized estimating equation models were used to assess the statistical significance of treatment outcomes by clinic and over time. Following intention-to-treat principles and based on previous sensitivity and cross-validation analyses showing that data is likely not missing at random, missing post-treatment and follow-up scores were imputed using separate GEE models with clinic, treatment adherence, and baseline symptoms as covariates [39,40]. An unstructured working correlation matrix and maximum likelihood estimation were used, and gamma distribution with a log link response scale was specified.
Clinical significance was assessed using effect sizes (Cohen’s d) and percentage changes. Negative outcomes were assessed by calculating reliable deterioration at post-treatment on the K-10. Score changes ≥7 were considered reliable [25,41]. A 0.05 significance level was used for all tests, and Bonferroni adjustments were used where required. Deidentified data were analyzed using SPSS version 27 (IBM, Chicago, IL, USA).

3. Results

3.1. Patient Flow

Patient flow for both clinics is shown in Figure 1. A total of 5206 referrals were made to PORTS within the study period, of which 4848 (93.1%) consented for analysis. A total of 1655 referrals (34.1%) were from Perth North, 2704 referrals (55.8%) from Perth South, and 489 referrals (10.1%) were from the country. In the same period, a total of 4154 patients from WA started a MindSpot assessment. Most (4080/4154; 98.2%) self-referred, and of these, almost one-third reported that they had never spoken to a health professional about their mental health (1306/4080; 32.0%). Of the 74 MindSpot patients who were directly referred by a health professional, 62 were referred by a GP, 7 by a counsellor, and 5 by a nurse practitioner.

3.2. Comparison of Patient Characteristics

There were significant differences between clinics in the demographic characteristics of the patients (Table 1). The mean age of patients from PORTS was significantly higher (39.4 years compared to 34.9 years at MindSpot), and there was a significantly higher proportion of male patients in the PORTS sample (35.5% compared to 24.6%). Patients from PORTS were less likely to have a tertiary education, less likely to be employed, and more likely to be separated, divorced, or widowed. PORTS patients were more likely to reside in urban regions, and in areas of higher socioeconomic disadvantage. Self-reported symptoms of depression and anxiety were higher in the PORTS cohort, but the proportion of patients reporting that they had a current plan for self-harm was significantly lower. Functional interference, indicated by the self-reported number of days patients were unable to undertake their usual activities, was significantly higher for the PORTS cohort (7.7 days out of role per month compared to 5.5 days for the MindSpot cohort).

3.3. Wellbeing Course Treatment Outcomes

On all symptom measures, patients from both clinics showed significant symptom reductions from assessment to post-treatment and three-month-follow-up on the K10 (Wald’s χ2 = 4286.8, p < 0.001), PHQ-2 (Wald’s χ2 = 1854.5, p < 0.001), and GAD-2 (Wald’s χ2 = 2379.5, p < 0.001). Clinic by time interaction effects were also observed, with the MindSpot cohort showing lower scores than the PORTS cohort at post-treatment and three-month follow-up on all measures (Figure 2).
Estimated means, effect sizes and percentage changes for patients starting the Wellbeing Course are shown in Table 2. Overall effect sizes and percentage changes were large for both clinics. For PORTS, effect sizes ranged from 0.90 to 1.16 at post-treatment, and from 1.03 to 1.28 at three-month follow-up. For MindSpot, effect sizes ranged from 1.00 to 1.34 at post-treatment, and from 1.27 to 1.58 at follow-up. For patients who completed the post-treatment symptom measures, clinical deterioration on the K-10 was low for both clinics: 2.7% (7/264) for MindSpot, and 2.6% (12/463) for PORTS.
Changes in whole days out of role at post-treatment were available for a subset of patients from both clinics (MindSpot: n = 107; PORTS: n = 263), and these scores were used to identify changes in functional impairment. For MindSpot patients who completed the post-treatment functional interference questions, the mean number of whole days out of role decreased from 6.7 days per month (SD = 7.0) to 3.7 of days per month (SD = 6.8). For PORTS patients, the mean number of whole days out of role decreased from 8.0 days per month (SD = 7.9) to 4.4 days per month (SD = 6.6). Within group effect sizes from assessment to post-treatment were 0.43 (CI 0.16–0.70) for MindSpot and 0.49 (CI 0.32–0.67) for PORTS.

3.4. Treatment Satisfaction

A total of 691 patients completed the treatment satisfaction questionnaires (259 from MindSpot and 432 from PORTS). Of the MindSpot patients, 95.8% (248) would recommend the Wellbeing Course to a friend, and 96.1% (249) reported that it was worth their time. Of the PORTS patients, 93.8% (405) would recommend the course to a friend, and 94.7% (409) stated that it was worth their time.

4. Discussion

PORTS and MindSpot are two DMHSs providing telephone and online psychological assessments, treatment and referral services to patients located in WA, Australia. Both clinics utilize comparable assessment, treatment, and data management processes, but have different referral pathways. PORTS is accessed by patients through referral from a primary health care provider and is designed to reach those who are financially, geographically, or otherwise disadvantaged. In contrast, MindSpot services are not targeted to a specific cohort and do not require referral. The current study compared patient characteristics and treatment outcomes for both clinics. Results showed that the clinics serve patients with significantly different demographic, socioeconomic, and geographic features. Despite these differences, outcomes were excellent for patients accessing online treatment through either clinic.
PORTS patients were more likely to be older, male, unemployed, and less likely to report a tertiary education. They reported more severe symptoms of anxiety and depression, and geographic indicators suggested higher levels of socioeconomic disadvantage. The pattern of observed patient characteristics was unsurprising given that PORTS is targeted toward people facing socioeconomic or geographic disadvantage or limited access to services for other reasons, especially those in remote locations. A pleasing feature of the PORTS cohort was the greater number of male patients, who are under-represented in outpatient mental health care settings. In contrast, MindSpot patient demographics corresponded closely with those of a recent survey of primary care consumers in Australia, which found that people using mental health websites were more likely to be female, younger, highly educated, and employed [42].
A higher proportion of MindSpot patients reported a current plan for self-harm (3.3% of MindSpot respondents compared to 1.9% of PORTS respondents). This may be expected because of the differences in referral pathways. Given that MindSpot patients usually self-refer and may never have previously spoken with a health professional, there is no opportunity to screen for suicidal thoughts or intentions until the assessment questions are answered. In contrast, individuals are referred to PORTS by their GP or health practitioner. This means they are more likely to have received a risk assessment by their primary health care provider and been referred to a more appropriate service if at imminent risk. Encouragingly, it should be noted that both PORTS and MindSpot have detailed risk assessment procedures in place for any patients who do disclose suicidal plans or intent [33].
A key finding from the current study was that both DMHSs were effective in providing triage, support, and education, as well as treatment. Many patients reported mainly seeking assessment and information about mental health conditions, which served as a brief intervention. For both clinics, around one in five patients enrolled in an online treatment course. Previous research indicates that many patients with symptoms of anxiety or depression do not initiate mental health treatment despite treatment availability [24,25,43]. This is likely due to complex interactions between attitudinal and structural barriers, and patient demographics and preferences [44]. The factors associated with treatment uptake for patients of MindSpot is a focus of current research [45], and this remains an important area for further investigation.
For patients who did enroll in the online Wellbeing Course through either clinic, treatment outcomes were excellent. Patients accessing online treatment via PORTS generally had more severe symptoms than those accessing the course via MindSpot, however effect sizes were large for both clinics, and symptoms reduced by 40% to 56%. Clinical deterioration on the K-10 was less than 3% for both clinics, and patient satisfaction was high. These outcomes are consistent with previous reports [24,25], and compare favorably with outcomes from other DMHSs that offer online treatment as part of routine care in public health systems around the world [46,47,48,49,50,51].
An important feature of DMHSs is the systematic collection of data, used for benchmarking and quality assurance, and to inform policy and funding decisions. The main strength of this study is the availability of comprehensive, real-world data, from two concurrently operating DMHSs using the same methods of data collection and analyses, and offering similar services, but via different health care pathways. This provided a unique opportunity to directly compare clinical flow, patient characteristics, and treatment outcomes within two publicly funded DMHSs, one of which targeted a distinct cohort of patients.
There are some limitations to the study. Interpretation of the results is limited by missing data, due to patients who were unable to be contacted, declined permission to analyze their data, or did not complete post-treatment or follow-up questionnaires. Missing data is a limitation of many studies, particularly those involving people who are accessing a service rather than participating in a research trial. However, the weekly collection of symptom scores during treatment and appropriate statistical modelling attempted to mitigate this limitation. It is also important to note that MindSpot and PORTS are well-established and well-regulated DMHSs, and services are delivered by trained mental health professionals, which may limit the generalizability of the results. Similarly, this study was restricted to a sample of patients from WA and different patterns may be found in other jurisdictions. Future research and evaluations are required to replicate these results in other primary health care settings, to ensure that evidence-based care is routinely available to patients in efficient and cost-effective ways.

5. Conclusions

Results showed that PORTS was able to successfully engage otherwise hard to reach populations via primary care referral pathways. Further, treatment outcomes were comparable to the MindSpot Clinic, where patients can access services directly. The implementation of DMHSs in routine care is a considerable challenge and requires clear evidence to assist those involved in service planning and policy development. It is hoped that the consistency of outcomes reported here, achieved via two different service models, will help Governments in Australia and other jurisdictions when developing their own models. Results provide further evidence for the accessibility, acceptability, and effectiveness of DMHSs regardless of referral pathway or patient characteristics.

Author Contributions

Conceptualization: N.T., B.F.D., N.W., D.R. and L.G.S.; Methodology: L.G.S. and L.A.; Analysis: L.G.S. and L.A.; Data Curation: L.G.S. and L.A.; Writing—Original Draft Preparation: L.G.S. and N.T.; Writing—Review & Editing: N.T., B.F.D., N.W., D.R., S.C., R.K., E.K., O.N. and L.G.S. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

Approval to conduct the study was obtained from the Human Research Ethics Committee at Macquarie University (5201200912).

Informed Consent Statement

Informed consent was obtained from all subjects involved in the study.

Data Availability Statement

Access to de-identified data may be provided to external researchers upon reasonable request. Requests must be made in writing and are subject to the establishment of appropriate data governance, and the approval of an independent and recognized Human Research Ethics Committee.

Acknowledgments

We wish to acknowledge the support and feedback from patients, GPs, Portals, WA Primary Health Alliance, and other stakeholders. We also thank the PORTS and MindSpot teams.

Conflicts of Interest

N.T. and B.F.D. are authors and developers of the treatment courses used at the MindSpot Clinic but derive no personal or financial benefit. N.T. serves as Chair of an Expert Advisory Group appointed to support the Australian Commission for Safety and Quality in Health Care to develop a national standards and certification framework for digital mental health services. All other authors declare no competing interests.

References

  1. Vos, T.; Abajobir, A.A.; Abate, K.H.; Abbafati, C.; Abbas, K.M.; Abd-Allah, F.; Abdulkader, R.S.; Abdulle, A.M.; Abebo, T.A.; Abera, S.F.; et al. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017, 390, 1211–1259. [Google Scholar] [CrossRef] [Green Version]
  2. Whiteford, H.A.; Degenhardt, L.; Rehm, J.; Baxter, A.J.; Ferrari, A.J.; Erskine, H.E.; Charlson, F.J.; Norman, R.E.; Flaxman, A.D.; Johns, N.; et al. Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010. Lancet 2013, 382, 1575–1586. [Google Scholar] [CrossRef]
  3. Mojtabai, R.; Olfson, M.; Sampson, N.A.; Jin, R.; Druss, B.; Wang, P.S.; Wells, K.B.; Pincus, H.A.; Kessler, R.C. Barriers to mental health treatment: Results from the National Comorbidity Survey Replication. Psychol. Med. 2011, 41, 1751–1761. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  4. Office of the Prime Minister. $1.1 Billion to Support More Mental Health, Medicare and Domestic Violence Services; Office of the Prime Minister: Canberra, Australia, 2020. [Google Scholar]
  5. Titov, N.; Staples, L.; Kayrouz, R.; Cross, S.; Karin, E.; Ryan, K.; Dear, B.; Nielssen, O. Rapid report: Early demand, profiles and concerns of mental health users during the coronavirus (COVID-19) pandemic. Internet Interv. 2020, 21, 100327. [Google Scholar] [CrossRef] [PubMed]
  6. Andrews, G.; Basu, A.; Cuijpers, P.; Craske, M.G.; McEvoy, P.; English, C.L.; Newby, J.M. Computer therapy for the anxiety and depression disorders is effective, acceptable and practical health care: An updated meta-analysis. J. Anxiety Disord. 2018, 55, 70–78. [Google Scholar] [CrossRef]
  7. Dear, B.F.; Staples, L.G.; Terides, M.D.; Fogliati, V.J.; Sheehan, J.; Johnston, L.; Kayrouz, R.; Dear, R.; McEvoy, P.M.; Titov, N. Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for Social Anxiety Disorder and comorbid disorders: A randomized controlled trial. J. Anxiety Disord. 2016, 42, 30–44. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  8. Dear, B.F.; Staples, L.G.; Terides, M.D.; Karin, E.; Zou, J.; Johnston, L.; Gandy, M.; Fogliati, V.J.; Wootton, B.M.; McEvoy, P.M.; et al. Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial. J. Anxiety Disord. 2015, 36, 63–77. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  9. Fogliati, V.J.; Dear, B.F.; Staples, L.G.; Terides, M.D.; Sheehan, J.; Johnston, L.; Kayrouz, R.; Dear, R.; McEvoy, P.M.; Titov, N. Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: A randomized controlled trial. J. Anxiety Disord. 2016, 39, 88–102. [Google Scholar] [CrossRef] [Green Version]
  10. Olthuis, J.V.; Watt, M.C.; Bailey, K.; Hayden, J.A.; Stewart, S.H. Therapist-supported Internet cognitive behavioural therapy for anxiety disorders in adults. Cochr. Database Syst. Rev. 2016, 3, CD011565. [Google Scholar] [CrossRef]
  11. Titov, N.; Dear, B.F.; Staples, L.G.; Terides, M.D.; Karin, E.; Sheehan, J.; Johnston, L.; Gandy, M.; Fogliati, V.J.; Wootton, B.M.; et al. Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial. J. Anxiety Disord. 2015, 35, 88–102. [Google Scholar] [CrossRef] [Green Version]
  12. Etzelmueller, A.; Vis, C.; Karyotaki, E.; Baumeister, H.; Titov, N.; Berking, M.; Cuijpers, P.; Riper, H.; Ebert, D.D. Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis. J. Med. Internet Res. 2020, 22, e18100. [Google Scholar] [CrossRef] [PubMed]
  13. Fu, Z.; Burger, H.; Arjadi, R.; Bockting, C.L.H. Effectiveness of digital psychological interventions for mental health problems in low-income and middle-income countries: A systematic review and meta-analysis. Lancet Psychiatry 2020, 7, 851–864. [Google Scholar] [CrossRef]
  14. Graham, A.K.; Lattie, E.G.; Powell, B.J.; Lyon, A.R.; Smith, J.D.; Schueller, S.M.; Stadnick, N.A.; Brown, C.H.; Mohr, D.C. Implementation strategies for digital mental health interventions in health care settings. Am. Psychol. 2020, 75, 1080–1092. [Google Scholar] [CrossRef] [PubMed]
  15. Gaebel, W.; Lukies, R.; Kerst, A.; Stricker, J.; Zielasek, J.; Diekmann, S.; Trost, N.; Gouzoulis-Mayfrank, E.; Bonroy, B.; Cullen, K.; et al. Upscaling e-mental health in Europe: A six-country qualitative analysis and policy recommendations from the eMEN project. Eur. Arch. Psychiatry Clin. Neurosci. 2021, 271, 1005–1016. [Google Scholar] [CrossRef]
  16. Brantnell, A.; Woodford, J.; Baraldi, E.; van Achterberg, T.; von Essen, L. Views of Implementers and Nonimplementers of Internet-Administered Cognitive Behavioral Therapy for Depression and Anxiety: Survey of Primary Care Decision Makers in Sweden. J. Med. Internet Res. 2020, 22, e18033. [Google Scholar] [CrossRef]
  17. Hadjistavropoulos, H.D.; Nugent, M.M.; Dirkse, D.; Pugh, N. Implementation of internet-delivered cognitive behavior therapy within community mental health clinics: A process evaluation using the consolidated framework for implementation research. BMC Psychiatry 2017, 17, 331. [Google Scholar] [CrossRef]
  18. Australian Institute of Health and Welfare. Mental Health Services in Australia; AIHW: Canberra, Australia, 2021. [Google Scholar]
  19. Australian Government. Budget Paper No. 1 Budget Strategy and Outlook; Australian Government: Canberra, Australia, 2021. [Google Scholar]
  20. Australian Government. E-Mental Health Strategy for Australia; Australian Government: Canberra, Australia, 2012. [Google Scholar]
  21. Australian Commission on Safety and Quality in Health Care. National Safety and Quality Digital Mental Health Standards; Australian Commission on Safety and Quality in Health Care: Sydney, Australia, 2020. [Google Scholar]
  22. Meurk, C.; Leung, J.; Hall, W.; Head, B.W.; Whiteford, H. Establishing and Governing e-Mental Health Care in Australia: A Systematic Review of Challenges and a Call For Policy-Focussed Research. J. Med. Internet Res. 2016, 18, e10. [Google Scholar] [CrossRef]
  23. Australian Government. Australian Government Response to Contributing Lives, Thriving Communities—Review of Mental Health Programmes and Services; Department of Health: Canberra, Australia, 2015. [Google Scholar]
  24. Titov, N.; Dear, B.F.; Nielssen, O.; Wootton, B.; Kayrouz, R.; Karin, E.; Genest, B.; Bennett-Levy, J.; Purtell, C.; Bezuidenhout, G.; et al. User characteristics and outcomes from a national digital mental health service: An observational study of registrants of the Australian MindSpot Clinic. Lancet Digit. Health 2020, 2, e582–e593. [Google Scholar] [CrossRef]
  25. Titov, N.; Rock, D.; Bezuidenhout, G.; Webb, N.; Kayrouz, R.; Nielssen, O.; Williams, L.; Purtell, C.; Dear, B.F.; Staples, L.G. Evaluation of The Practitioner Online Referral and Treatment Service (PORTS): The first 18 months of a state-wide digital service for adults with anxiety, depression, or substance use problems. Cogn. Behav. Ther. 2020, 49, 307–326. [Google Scholar] [CrossRef]
  26. von Elm, E.; Altman, D.G.; Egger, M.; Pocock, S.J.; Gøtzsche, P.C.; Vandenbroucke, J.P. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. Ann. Intern. Med. 2007, 147, 573–577. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  27. Staples, L.; Nielssen, O.; Kayrouz, R.; Cross, S.; Karin, E.; Ryan, K.; Dear, B.; Titov, N. Rapid report 2: Symptoms of anxiety and depression during the first 12 weeks of the Coronavirus (COVID-19) pandemic in Australia. Internet Interv. 2020, 22, 100351. [Google Scholar] [CrossRef]
  28. Staples, L.; Nielssen, O.; Kayrouz, R.; Cross, S.; Karin, E.; Ryan, K.; Dear, B.; Titov, N. Rapid Report 3: Mental health symptoms, characteristics, and regional variation, for users of an Australian digital mental health service during the first 8 months of COVID-19. Internet Interv. 2021, 24, 100378. [Google Scholar] [CrossRef] [PubMed]
  29. Staples, L.G.; Dear, B.F.; Johnson, B.; Fogliati, V.; Gandy, M.; Fogliati, R.; Nielssen, O.; Titov, N. Internet-delivered treatment for young adults with anxiety and depression: Evaluation in routine clinical care and comparison with research trial outcomes. J. Affect. Disord. 2019, 256, 103–109. [Google Scholar] [CrossRef]
  30. Staples, L.G.; Fogliati, V.J.; Dear, B.F.; Nielssen, O.; Titov, N. Internet-delivered treatment for older adults with anxiety and depression: Implementation of the Wellbeing Plus Course in routine clinical care and comparison with research trial outcomes. BJPsych Open 2016, 2, 307–313. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  31. Kayrouz, R.; Karin, E.; Staples, L.G.; Nielssen, O.; Dear, B.F.; Titov, N. A comparison of the characteristics and treatment outcomes of migrant and Australian-born users of a national digital mental health service. BMC Psychiatry 2020, 20, 111. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  32. Australian Bureau of Statistics. Census of Population and Housing: Socio-Economic Indexes for Areas (SEIFA), Australia, 2016; Australian Bureau of Statistics: Canberra, Australia, 2018. [Google Scholar]
  33. Nielssen, O.; Dear, B.F.; Staples, L.G.; Dear, R.; Ryan, K.; Purtell, C.; Titov, N. Procedures for risk management and a review of crisis referrals from the MindSpot Clinic, a national service for the remote assessment and treatment of anxiety and depression. BMC Psychiatry 2015, 15, 304. [Google Scholar] [CrossRef] [Green Version]
  34. Kessler, R.C.; Andrews, G.; Colpe, L.J.; Hiripi, E.; Mroczek, D.K.; Normand, S.L.; Walters, E.E.; Zaslavsky, A.M. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol. Med. 2002, 32, 959–976. [Google Scholar] [CrossRef]
  35. Kroenke, K.; Spitzer, R.L.; Williams, J.B.W. The Patient Health Questionnaire-2: Validity of a two-item depression screener. Med. Care 2003, 41, 1284–1292. [Google Scholar] [CrossRef]
  36. Kroenke, K.; Spitzer, R.L.; Williams, J.B.; Lowe, B. An ultra-brief screening scale for anxiety and depression: The PHQ-4. Psychosomatics 2009, 50, 613–621. [Google Scholar] [CrossRef]
  37. Staples, L.G.; Dear, B.F.; Gandy, M.; Fogliati, V.; Fogliati, R.; Karin, E.; Nielssen, O.; Titov, N. Psychometric properties and clinical utility of brief measures of depression, anxiety, and general distress: The PHQ-2, GAD-2, and K-6. Gen. Hosp. Psychiatry 2019, 56, 13–18. [Google Scholar] [CrossRef]
  38. Kroenke, K.; Spitzer, R.L.; Williams, J.B.; Monahan, P.O.; Lowe, B. Anxiety disorders in primary care: Prevalence, impairment, comorbidity, and detection. Ann. Intern. Med. 2007, 146, 317–325. [Google Scholar] [CrossRef]
  39. Karin, E.; Crane, M.F.; Dear, B.F.; Nielssen, O.; Heller, G.Z.; Kayrouz, R.; Titov, N. Predictors, Outcomes, and Statistical Solutions of Missing Cases in Web-Based Psychotherapy: Methodological Replication and Elaboration Study. JMIR Ment. Health 2021, 8, e22700. [Google Scholar] [CrossRef]
  40. Karin, E.; Dear, B.F.; Heller, G.Z.; Gandy, M.; Titov, N. Measurement of Symptom Change Following Web-Based Psychotherapy: Statistical Characteristics and Analytical Methods for Measuring and Interpreting Change. JMIR Ment. Health 2018, 5, e10200. [Google Scholar] [CrossRef]
  41. Rozental, A.; Andersson, G.; Boettcher, J.; Ebert, D.D.; Cuijpers, P.; Knaevelsrud, C.; Ljótsson, B.; Kaldo, V.; Titov, N.; Carlbring, P. Consensus statement on defining and measuring negative effects of Internet interventions. Internet Interv. 2014, 1, 12–19. [Google Scholar] [CrossRef] [Green Version]
  42. Gunn, J.; Cameron, J.; Densley, K.; Davidson, S.; Fletcher, S.; Palmer, V.; Chondros, P.; Dowrick, C.; Pirkis, J. Uptake of mental health websites in primary care: Insights from an Australian longitudinal cohort study of depression. Patient Educ. Couns. 2018, 101, 105–112. [Google Scholar] [CrossRef]
  43. Whiteford, H.A.; Buckingham, W.J.; Harris, M.G.; Burgess, P.M.; Pirkis, J.E.; Barendregt, J.J.; Hall, W.D. Estimating treatment rates for mental disorders in Australia. Aust. Health Rev. 2014, 38, 80–85. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  44. Moskalenko, M.Y.; Hadjistavropoulos, H.D.; Katapally, T.R. The complex association of barriers and interest in internet-delivered cognitive behavior therapy for depression and anxiety: Informing e-health policies through exploratory path analysis. J. Ment. Health 2020. [Google Scholar] [CrossRef]
  45. Cross, S.; Karin, E.; Staples, L.; Bisby, M.; Ryan, K.; Duke, G.; Nielssen, O.; Kayrouz, R.; Fisher, A.; Dear, B.; et al. Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service. Submitted to Internet Interv. 2021. [Google Scholar]
  46. Andersson, G.; Titov, N.; Dear, B.F.; Rozental, A.; Carlbring, P. Internet-delivered psychological treatments: From innovation to implementation. World Psychiatry 2019, 18, 20–28. [Google Scholar] [CrossRef] [Green Version]
  47. Hadjistavropoulos, H.D.; Peynenburg, V.; Thiessen, D.L.; Nugent, M.; Karin, E.; Staples, L.; Dear, B.F.; Titov, N. Utilization, Patient Characteristics, and Longitudinal Improvements among Patients from a Provincially Funded Transdiagnostic Internet-delivered Cognitive Behavioural Therapy Program: Observational Study of Trends over 6 Years: Utilisation, caractéristiques des patients et améliorations longitudinales chez les patients d’un programme de thérapie cognitivo-comportementale financé par la province, transdiagnostique et dispensé par internet: Une étude observationnelle des tendances sur six ans. Can. J. Psychiatry 2021, 7067437211006873. [Google Scholar] [CrossRef]
  48. Nordgreen, T.; Blom, K.; Andersson, G.; Carlbring, P.; Havik, O.E. Effectiveness of guided Internet-delivered treatment for major depression in routine mental healthcare—An open study. Internet Interv. 2019, 18, 100274. [Google Scholar] [CrossRef] [PubMed]
  49. Ruwaard, J.; Lange, A.; Schrieken, B.; Dolan, C.V.; Emmelkamp, P. The effectiveness of online cognitive behavioral treatment in routine clinical practice. PLoS ONE 2012, 7, e40089. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  50. Thew, G.R. IAPT and the internet: The current and future role of therapist-guided internet interventions within routine care settings. Cogn. Behav. Ther. 2020, 13, e4. [Google Scholar] [CrossRef] [PubMed] [Green Version]
  51. Williams, A.D.; Andrews, G. The Effectiveness of Internet Cognitive Behavioural Therapy (iCBT) for Depression in Primary Care: A Quality Assurance Study. PLoS ONE 2013, 8, e57447. [Google Scholar] [CrossRef] [Green Version]
Figure 1. Patient Flow.
Figure 1. Patient Flow.
Ijerph 19 00905 g001
Figure 2. Comparison of symptom reductions for PORTS and MindSpot, from assessment to post-treatment and 3-month follow-up. Error bars represent 95% confidence intervals. Means and standard deviations for each time point are shown in Table 2.
Figure 2. Comparison of symptom reductions for PORTS and MindSpot, from assessment to post-treatment and 3-month follow-up. Error bars represent 95% confidence intervals. Means and standard deviations for each time point are shown in Table 2.
Ijerph 19 00905 g002
Table 1. Demographic characteristics of patients referred to MindSpot (n = 4154) and PORTS (n = 4848).
Table 1. Demographic characteristics of patients referred to MindSpot (n = 4154) and PORTS (n = 4848).
MindSpotPORTSSig.
Age
Mean age (SD)34.9 (13.6)39.4 (15.8)F = 211.3; p < 0.001 ***
Age range18–93 years16–95 years
Gender
Female74.7% (3103/4154) a62.6% (3034/4848) bχ2 = 158.9, p < 0.001 ***
Male24.6% (1021/4154) a35.5% (1722/4848) b
Other0.7% (30/4154) a1.9% (92/4848) b
Cultural identity
Aboriginal or Torres Strait Islander3.1% (118/3832)3.6% (95/2644)χ2 = 3.2, p = 0.199
Born in Australia: non-Indigenous67.8% (2589/3832)65.8% (1741/2644)
Born in country other than Australia29.1% (1116/3832)30.6% (808/2644)
Education
Postgraduate degree15.6% (602/3871) a5.9% (156/2644) bχ2 = 321.8, p < 0.001 ***
Undergraduate degree21.6% (837/3871) a11.7% (310/2644) b
Other tertiary qualification29.9% (1157/3871) a33.4% (883/2644) b
No tertiary qualification32.9% (1275/3871) a49.0% (1295/2644) b
Employment
Employed full or part-time57.4% (2226/3877) a42.2% (1116/2644) bχ2 = 145.6, p < 0.001 ***
Unemployed12.0% (465/3877) a16.0% (423/2644) b
Other30.6% (1186/3877) a41.8% (1105/2644) b
Marital status
Married (registered or de facto)37.5% (1453/3871) a34.1% (902/2644) bχ2 = 90.9, p < 0.001 ***
Separated5.8% (225/3871) a10.1% (266/2644) b
Divorced5.8% (225/3871) a7.6% (201/2644) b
Widowed0.7% (28/3871) a2.5% (66/2644) b
Other50.1% (1940/3871) a45.7% (1209/2644) a
Self-described location
Capital city or surrounding suburbs71.3% (2757/3869) a74.8% (1977/2644) bχ2 = 37.8, p < 0.001 ***
Other urban area11.2% (435/3869) a13.2% (348/2644) b
Rural or remote region17.5% (677/3869) a12.1% (319/2644) b
IRSD
First quintile (most disadvantaged)10.0% (402/4031) a16.1% (777/4826) bχ2 = 173.2, p < 0.001 ***
Second quintile23.0% (926/4031) a26.6% (1286/4826) b
Third quintile20.2% (814/4031) a23.0% (1109/4826) b
Fourth quintile20.9% (844/4031) a16.5% (798/4826) b
Fifth quintile (least disadvantaged)25.9% (1045/4031) a17.7% (856/4826) b
Symptoms and impairment
General distress (K-10)31.1 (7.4)31.5 (8.0)F = 2.8, p = 0.093
Self-reported current depression69.7% (2662/3820)78.3% (2071/2645)χ2 = 0.59.1, p < 0.001 ***
Self-reported current anxiety87.3% (3333/3820)89.7% (2373/2645)χ2 = 0.9.2, p = 0.002 **
Thoughts of suicide in last week29.1% (1051/3615)27.2% (720/2644)χ2 = 2.6, p = 0.110
Current plan for self-harm3.3% (118/3615)1.9% (50/2644)χ2 = 11.0, p < 0.001 ***
Whole days out of role in last month5.5 (7.5)7.7 (8.9)F = 94.1, p < 0.001 ***
** Significant at p < 0.01; *** Significant at p < 0.001. Each superscript (a,b) letter denotes a subset whose proportions differ significantly from other subsets at the 0.05 level.
Table 2. Treatment outcomes for patients enrolled in the Wellbeing Course at MindSpot (n = 425) and PORTS (n = 780).
Table 2. Treatment outcomes for patients enrolled in the Wellbeing Course at MindSpot (n = 425) and PORTS (n = 780).
Estimated Marginal MeansEffect Size from AssessmentPercentage Change from Assessment
nAssessmentPost-Treatment3-Month Follow-UpTo Post-TreatmentTo 3-Month Follow-UpTo Post-TreatmentTo 3-Month Follow-Up
K-10
MindSpot42529.8 (6.7)20.8 (6.9) ***19.5 (5.4) ***1.32
[1.17–1.47]
1.69
[1.53–1.85]
45.2%
[41.8%–48.4%]
52.4%
[49.8%–55.0%]
PORTS78030.6 (7.4)22.2 (7.5) ***22.0 (6.4) ***1.13
[1.02–1.23]
1.24
[1.13–1.35]
40.9%
[38.3%–43.5%]
41.8%
[39.6%–44.0%]
PHQ-2
MindSpot4253.2 (1.6)1.7 (1.4) ***1.4 (1.2) ***1.00
[0.85–1.14]
1.27
[1.12–1.42]
47.9%
[43.6%–52.0%]
56.1%
[52.5%–59.4%]
PORTS7803.4 (1.8)2.0 (1.5) ***1.8 (1.5) ***0.85
[0.74–0.95]
0.97
[0.86–1.07]
41.4%
[38.2%–44.5%]
46.5%
[43.3%–49.4%]
GAD-2
MindSpot4253.8 (1.6)1.9 (1.4) ***1.7 (1.1) ***1.26
[1.12–1.41]
1.53
[1.38–1.68]
50.1%
[46.6%–53.5%]
54.6%
[51.6%–57.3%]
PORTS7803.7 (1.7)2.2 (1.5) ***1.9 (1.2) ***0.94
[0.83–1.04]
1.22
[1.11–1.33]
40.5%
[37.6%–43.3%]
48.8%
[46.5%–51.1%]
Standard deviations are shown in round parentheses for the estimated marginal means, and 95% confidence intervals are shown in square parentheses for the effect sizes and percentage changes. *** Significant at p < 0.001 compared assessment.
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Share and Cite

MDPI and ACS Style

Staples, L.G.; Webb, N.; Asrianti, L.; Cross, S.; Rock, D.; Kayrouz, R.; Karin, E.; Dear, B.F.; Nielssen, O.; Titov, N. A Comparison of Self-Referral and Referral via Primary Care Providers, through Two Similar Digital Mental Health Services in Western Australia. Int. J. Environ. Res. Public Health 2022, 19, 905. https://doi.org/10.3390/ijerph19020905

AMA Style

Staples LG, Webb N, Asrianti L, Cross S, Rock D, Kayrouz R, Karin E, Dear BF, Nielssen O, Titov N. A Comparison of Self-Referral and Referral via Primary Care Providers, through Two Similar Digital Mental Health Services in Western Australia. International Journal of Environmental Research and Public Health. 2022; 19(2):905. https://doi.org/10.3390/ijerph19020905

Chicago/Turabian Style

Staples, Lauren G., Nick Webb, Lia Asrianti, Shane Cross, Daniel Rock, Rony Kayrouz, Eyal Karin, Blake F. Dear, Olav Nielssen, and Nickolai Titov. 2022. "A Comparison of Self-Referral and Referral via Primary Care Providers, through Two Similar Digital Mental Health Services in Western Australia" International Journal of Environmental Research and Public Health 19, no. 2: 905. https://doi.org/10.3390/ijerph19020905

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop