Understanding Primary Care Physician Vaccination Behaviour: A Systematic Review
Abstract
:1. Introduction
2. Material and Methods
2.1. Study Protocol and Registration
2.2. Search Strategy
2.3. Inclusion and Exclusion Criteria
2.4. Data-Extraction and Analysis
2.5. Quality Assessment
Author | Year | Country | Study Population | Number and Type of Primary Care Participants | Response Rate (%) | Vaccine | Data-Collection Method (Questionnaire) | Final NOS Score |
---|---|---|---|---|---|---|---|---|
With statistical hypothesis testing betweenKBAB and own vaccination and patient recommendation | ||||||||
Verger P et al. [21] | 2021 | France | GP | 2755 GP | 43.9 T | COVID-19 | Online | 7 |
Verger P et al. [22] | 2021 | France | GP | 2755 GP | 29 T | COVID-19 | Online | 7 |
Arlt J et al. [23] | 2021 | Germany | GP | 308 FM, 111 IM, 24 WS (443) | 28.0 E | Influenza | 7 | |
Neufeind J et al. [24] | 2020 | Germany | FP | 735 FP | 20.4 E | Adult vaccination: influenza, pertussis, hepatitis B, measles, DT | Phone | 6 |
Verhees RAF et al. [25] | 2020 | Netherlands | GP | 552 GP | 31.7 E | Influenza | Online | 5 |
Vezzosi L et al. [26] | 2019 | Italy | GP | 73 GP | 26.6 T | Adults ≥ 65: Seasonal Influenza (SI), Pneumococcus (PNV), Zoster (ZV) | Online | 3 |
Yilmaz-Karadağ F et al. [27] | 2019 | Turkey | PCP | 49 FP, 172 GP (221) | 14.7 T | Adult risk groups: Influenza, Td, pneumococcal, meningococcal, HBV, HAV | Online | 5 |
Akan H et al. [28] | 2016 | Turkey | FP | 606 | 27.5 E | Influenza | Online | 4 |
Klett-Tammen CJ et al. [29] | 2016 | Germany | GP, PA | 774 GP | 13.4 E | Vaccines for the elderly: tetanus, influenza, pneumococcal | 6 | |
Verger P et al. [30] | 2015 | France | GP | 1582 GP | 42.5 E | Influenza, hepatitis B, MMR, HPV, MenC, | Telephone | 6 |
Flicoteaux R et al. [31] | 2014 | France | GP | 1431 GP | 36.8 E | Pandemic Influenza A/H1N1 | Telephone | 4 |
Pulcini C et al. [32] | 2013 | France | GP | 1431 GP | 36.8 E | Hepatitis B, pertussis, seasonal and pandemic influenza | Telephone | 5 |
Pulcini C et al. [33] | 2014 | France | GP | 329 GP | 36.3 E | MMR | Telephone | 3 |
Verger P et al. [34] | 2012 | France | GP | 1431 GP | 36.8 E | Pandemic Influenza A:H1N1 | Telephone | 6 |
NOstatistical hypothesis testing betweenKBAB and own vaccination and patient recommendation | ||||||||
Deruelle et al. [35] | 2021 | USA | GP, OB/GYN | 69 GP | 81.1 T | COVID-19 | Online | 5 |
Bayliss J et al. [36] | 2021 | Australia | GP, AC | 412 GP | - | Adult vaccination (focus: pertussis) Influenza, Td, HBV, HBA, polio | - | 3 |
Hurley LP et al. [37] | 2021 | USA | PCP | 336 FP, 281 GIM (617) | 64.0 E | HPV | Mail or online | 4 |
Napolitano F et al. [38] | 2021 | Italy | GP | 349 GP | 61.5 E | HPV | Online or Telephone | 7 |
Celep G et al. [39] | 2020 | Turkey | PHW | 97 FP | - | Pregnancy (Td, Tdap, HBV, influenza) | Online or Telephone | 3 |
Kalemaki D et al. [40] | 2020 | Greece | GP | 260 GP | 88.0 E | Influenza, measles, HBV, pertussis, Tdap | Online or Telephone | 4 |
Meites E et al. [41] | 2020 | USA | PCP | 266 FM, 235 GIM (430) | 59.3 E | HPV | Mail or online | 6 |
Awadlla NJ et al. [42] | 2019 | Saudi Arabia | PHW | 74 PCP | 77.0 E | Seasonal Influenza | Personally | 6 |
Collange F et al. [43] | 2019 | France | GP | 2586 GP | 37.6 E | MMR, MenC, HBV, seasonal influenza, HPV | Telephone | 5 |
Glavier M et al. [44] | 2019 | France | GP | 287 GP | 21.9 E | Vaccination practices with chemotherapy patients: influenza, pneumococcal, DTP | Fax, mail or online | 5 |
Hurley LP et al. [45] | 2018 | USA | PCP | FP, GIM (603) | 65.0 E | Zoster Vaccine Live (ZVL) and New Recombinant Zoster Vaccine (RZV) | Mail or online | 5 |
Le Marechal M et al. [46] | 2018 | France | GP | 1582 GP | 42.5 E | Seasonal Influenza, HBV, HPV | Telephone | 5 |
Levi M et al. [47] | 2018 | Italy | GP | 1245 GP | 12.4 E | Seasonal Influenza | Online | 4 |
Merriel SWD et al. [48] | 2018 | UK | GP, SHCP | 38 GP | - | HPV | Online | 5 |
Steben M et al. [49] | 2018 | Canada | GP, OB/GYN | 378 GP | 8.0 E | HPV | Online | 5 |
Desiante F et al. [50] | 2017 | Italy | GP | 229 GP | 48.6 E | Influenza | Online | 3 |
Hurley LP et al. [51] | 2017 | USA | PCP | 317 GIM, 236 FP (553) | 66.4 E | Adult vaccination: zoster, hepatitis B, Tdap, hepatitis A, HPV, Meningococcal, chicken pox, Td, PVC13, seasonal influenza, PPSV23, MMR | Mail or online | 4 |
Hurley LP et al. [52] | 2016 | USA | PCP | 352 GIM, 255 FP (607) | 71.8 E | Adult vaccination: seasonal influenza, pneumococcal, Tdap, Td, herpes zoster, MMR | Mail or online | 7 |
Raude J et al. [53] | 2016 | France | GP | 1582 GP | 92.4 E | MMR, MenC, HPV, HBV, seasonal influenza | Telephone | 7 |
Verger P et al. [54] | 2016 | France | GP | 1582 GP | 46 E | Influenza, dTP, HBV, MMR, MenC, HPV | Telephone | 6 |
Massin S et al. [55] | 2015 | France | GP | 1136 GP | 29.2 E | Influenza | Telephone | 3 |
Alsaleem MA [56] | 2013 | Saudi Arabia | PHW | 95 PCP | 81.2 E | H1N1 vaccine | - | 4 |
François M et al. [57] | 2011 | France | FP | 341 FP | 17.0 E | Hepatitis B | Online | 4 |
Inoue Y et al. [58] | 2011 | Japan | GP | 515 GP | 51.5 T | Novel Pandemic Vaccine Influenza A/H1N1 | 6 | |
Lutringer-Magnin D et al. [59] | 2011 | France | GP | 279 GP | 93.0 T | HPV | 6 | |
Rurik I et al. [60] | 2011 | Hungary | FP | 198 FP | 85.0 E | Pandemic Influenza | Personally | 3 |
Ward K et al. [61] | 2011 | Australia | HCW | 79 GP | 36.0 E | Annual Influenza Vaccination | 4 |
Author | Age | Gender | Status | Experience (Years of Practice) | No. Patients | Type of Practice (Single/Group) | Occasional Practice Alternative Medicine |
---|---|---|---|---|---|---|---|
Statistical hypothesis testing betweenKBAB and own vaccination and patient recommendation | |||||||
Verger P et al. [21] | ♀: ↓ | ||||||
Verger P et al. [22] | >age: ↑ | ♀: ↓ | |||||
Arlt J et al. [23] | |||||||
Neufeind J et al. [24] | >age: ↓ [OV] >age: ↓ MEAS [PR] | ♂: ↑ MEAS [PR] | Yes: ↓ INF [PR] | ||||
Verhees RAF et al. [25] | ≥60: ↑ [OV] | ♂: ↑ [OV] | |||||
Vezzosi L et al. [26] | |||||||
Yilmaz-Karadağ F et al. [27] | 31–40: ↑ INF + Td + HBV [OV] 31–40: ↑ INF + Td + PNV [PR] | ♀: ↑ INF [OV] ♂: ↑ PNV + Td [PR] | ≅ | ≅ | |||
Akan H et al. [28] | >age: ↑ [OV] | ≅ | >years: ↑ [OV] | ||||
Klett-Tammen CJ et al. [29] | |||||||
Verger P et al. [30] | |||||||
Flicoteaux R et al. [31] | |||||||
Pulcini C et al. [32] | <age: ↑ [OV] | >no.: ↑ [OV] | ≅ | Yes: ↓ [OV] | |||
Pulcini C et al. [33] | ≅ | ≅ | ≅ | ≅ | ≅ | ||
Verger P et al. [34] | ≅ | ≅ | ≅ | Group: ↑ [OV] | Yes: ↓ [OV] | ||
NOstatistical hypothesis testing betweenKBAB and own vaccination and patient recommendation | |||||||
Deruelle et al. [35] | |||||||
Bayliss J et al. [36] | |||||||
Hurley LP et al. [37] | |||||||
Napolitano F et al. [38] | |||||||
Celep G et al. [39] | |||||||
Kalemaki D et al. [40] | <age: ↑ MEAS [OV] <age: ↓ INF [OV] | ♀: ↑ HBV [OV] | |||||
Meites E et al. [41] | |||||||
Awadlla NJ et al. [42] | |||||||
Collange F et al. [43] | |||||||
Glavier M et al. [44] | ≅ | ||||||
Hurley LP et al. [45] | FP: ↑ ZVL [PR] | Small: ↑ ZVL [PR] | |||||
Le Marechal M et al. [46] | |||||||
Levi M et al. [47] | >age: ↑ seasonal INF >age: ↓ Td [OV] | ♂: ↑ seasonal INF, pandemic INF, PNV [OV] | >years: ↑ PNV >40 years: ↑ pandemic INF | ||||
Merriel SWD et al. [48] | |||||||
Steben M et al. [49] | ≅ | ||||||
Desiante F et al. [50] | ≅ | ♂: ↑ [OV] | ≅ | >no.: ↑ [OV] | |||
Hurley LP et al. [51] | ≅ | ||||||
Hurley LP et al. [52] | |||||||
Raude J et al. [53] | |||||||
Verger P et al. [54] | ≅ | ≅ | ≅ | Yes: ↓ | |||
Massin S et al. [55] | >age: ↑ pandemic INF [OV] | ♀: ↓ seasonal INF [OV] | High: ↑ seasonal + pandemic INF [OV] pandemic INF [PR] | Group: ↑ seasonal + pandemic INF [OV] | Yes: ↓ seasonal + pandemic INF [OV] | ||
Alsaleem MA [56] | |||||||
François M et al. [57] | >age: ↑ [PR] | ≅ | >3/day: ↑ [PR] | Yes: ↓ [PR] | |||
Inoue Y et al. [58] | |||||||
Lutringer-Magnin D et al. [59] | |||||||
Rurik I et al. [60] | |||||||
Ward K et al. [61] |
Author | Data and Data-Sources | Knowledge | Safety | Efficacy/Benefits | Perceived Risk | Trust | Protection | Important |
---|---|---|---|---|---|---|---|---|
Verger P et al. [21] | - | - | Safe OR: 1.93 | - | No perceived risk OR: 0.47 | Trust in institutions OR: 0.86 | - | - |
Verger P et al. [22] | - | - | Safe OR:0.27 | - | Perceived risk OR: 7.56 | Trust in institutions OR: 0.10 | - | - |
Arlt J et al. [23] | Co-workers OR: 2.26 Media News OR: 0.16 | - | - | - | - | - | - | - |
Neufeind J et al. [24] | Official Sources OR: 6.95 [INF] [PR] | - | Safe OR: 1.64 [INF] [PR] Safe OR: 1.28 [MEAS] [PR] Safe OR: 1.42 [INF, PER, HBV] [OV] | - | - | Trust in institutions OR: 1.43 [INF] [PR] | - | No importance OR: 0.71 [INF, PER, HBV] [OV] |
Verhees RAF et al. [25] | - | - | - | Efficacy p = 0.00 [OV] | - | - | - | - |
Vezzosi L et al. [26] | - | GAP OR: 0.07 [ZV] [PR] | - | - | - | - | - | - |
Yilmaz-Karadağ F et al. [27] | - | - | - | - | - | - | - | - |
Akan H et al. [28] | - | - | Safe 1.55 < OR < 2.45 Median (OR): 2.08 | Benefits 5.18 < OR < 9.29 Median (OR): 8.73 | Perceived Risk 1.77 < OR < 7.49 Median (OR): 4.27 [OV] | Trust in institutions OR: 2.52 | Natural Protection OR: 0.39 | - |
Klett-Tammen CJ et al. [29] | - | - | - | - | - | - | - | - |
Verger P et al. [30] | - | - | - | - | - | - | - | - |
Flicoteaux R et al. [31] | Official Sources OR: 2.03 Media News OR: 0.57 | - | Safe OR:0.17 [PR] | Efficacy OR: 0.28 [PR] | No Perceived Risk OR:0.6 [PR] | - | - | - |
Pulcini C et al. [32] | Internet OR: 0.92 [INF] | - | - | - | - | - | - | - |
Pulcini C et al. [33] | Official Sources OR: 7.37 | - | - | - | No Dangerous disease OR: 0.32 [MEAS] [PR] | - | - | - |
Verger P et al. [34] | Official Sources p < 0.0001 No Media News p < 0.0001 | - | Safe p < 0.0001 | Efficacy p < 0.0001 | Perceived Risk, Dangerous Disease p < 0.0001 | Trust in institutions p < 0.0001 [OV] | - | - |
Author | Responsibility | Attitude | Extrinsic Factors | Practices (Behaviors) | Experiences | |||
Verger P et al. [21] | - | - | - | - | - | |||
Verger P et al. [22] | - | - | - | - | - | |||
Arlt J et al. [23] | - | - | Organizational Factor OR: 4.31 [P] Patient Facilitator OR: 3.20 | - | - | |||
Neufeind J et al. [24] | Responsibility OR: 1.82 [INF, PER, HBV] [OV] | - | - | Vaccination History OR: 44.09 [INF] [R] | - | |||
Verhees RAF et al. [25] | - | - | - | - | - | |||
Vezzosi L et al. [26] | - | Attitude + OR: 13.67 [PNV, ZV] [R] | - | Vaccination History OR: 5.44 [PNV] [R] Vaccination History OR: 19.36 [ZV] [R] | Patient Experience OR: 6.61 [ZV] [R] | |||
Yilmaz-Karadağ F et al. [27] | - | - | - | Vaccination History p > 0.05 [R] | - | |||
Akan H et al. [28] | - | Attitude + 3.06 < OR < 10.93 Median (OR): 7.245 | Organizational Factor 2.64 < OR < 13.75 Median (OR): 6.57 | Vaccination History OR: 15.1 Reminder System OR:1.66 | - | |||
Klett-Tammen CJ et al. [29] | - | - | - | - | - | |||
Verger P et al. [30] | - | - | - | Vaccination History OR: 2.95 [INF] [R] Vaccination History OR: 1.90 [HBV] [R] | - | |||
Flicoteaux R et al. [31] | - | - | - | - | Patient Experience OR: 2.81 [R] PE (30.2%) | |||
Pulcini C et al. [32] | - | - | - | Vaccination History 1.08 < OR < 3.08 Mediana (OR): 1.2 [P] | - | |||
Pulcini C et al. [33] | - | - | - | Check vaccination status OR: 3.38 | - | |||
Verger P et al. [34] | - | - | - | - | - |
3. Results
3.1. Search Results
3.2. Quality Assessment
3.3. Characteristics of Selected Studies
3.4. Vaccines in General
3.4.1. Studies without Statistical Hypothesis Testing between KBAB and Own Vaccination and Patient Recommendation
3.4.2. Studies with Statistical Hypothesis Testing between KBAB and Own Vaccination and Patient Recommendation
3.5. Influenza Vaccines
3.5.1. Studies without Statistical Hypothesis Testing between KBAB and Own Vaccination and Patient Recommendation
3.5.2. Studies with Statistical Hypothesis Testing between KBAB and Own Vaccination and Patient Recommendation
3.6. HPV Vaccines
Studies without Statistical Hypothesis Testing between KBAB and Own Vaccination and Patient Recommendation
3.7. COVID-19 Vaccines
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Prieto-Campo, Á.; García-Álvarez, R.M.; López-Durán, A.; Roque, F.; Herdeiro, M.T.; Figueiras, A.; Zapata-Cachafeiro, M. Understanding Primary Care Physician Vaccination Behaviour: A Systematic Review. Int. J. Environ. Res. Public Health 2022, 19, 13872. https://doi.org/10.3390/ijerph192113872
Prieto-Campo Á, García-Álvarez RM, López-Durán A, Roque F, Herdeiro MT, Figueiras A, Zapata-Cachafeiro M. Understanding Primary Care Physician Vaccination Behaviour: A Systematic Review. International Journal of Environmental Research and Public Health. 2022; 19(21):13872. https://doi.org/10.3390/ijerph192113872
Chicago/Turabian StylePrieto-Campo, Ángela, Rosa María García-Álvarez, Ana López-Durán, Fátima Roque, Maria Teresa Herdeiro, Adolfo Figueiras, and Maruxa Zapata-Cachafeiro. 2022. "Understanding Primary Care Physician Vaccination Behaviour: A Systematic Review" International Journal of Environmental Research and Public Health 19, no. 21: 13872. https://doi.org/10.3390/ijerph192113872