Efficacy of Adductor Canal Block on Medial Knee Pain in Patients with Knee Osteoarthritis: A Randomized Single-Blind Placebo-Controlled Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Population
2.2. Intervention
2.3. Outcome Measurements
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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ACB Group (n = 15) | Placebo Group (n = 16) | p-Value | |
---|---|---|---|
Age, y | 76.8 ± 8.9 | 66.3 ± 9.9 | 0.008 * |
Sex, men:women, n | 3:12 | 4:12 | 0.539 |
Duration of symptoms, y | 8.5 ± 5.2 | 9.0 ± 6.3 | 0.892 |
Body mass index, kg/m2 | 25.7 ± 5.6 | 26.9 ± 6.4 | 0.800 |
Kellgren–Lawrence grade, 2:3:4, n | 0:4:11 | 2:4:10 | 0.595 |
Site, right:left:both, n | 3:1:11 | 3:0:13 | 0.820 |
NRS score | 7.1 ± 1.6 | 7.3 ± 1.2 | 0.800 |
WOMAC | 54.6 ± 15.3 | 53.7 ± 11.3 | 0.851 |
Average daily no. of analgesics consumed, n | 2.4 ± 2.2 | 2.8 ± 2.5 | 0.740 |
Average daily opioid consumption, mg | 8.2 ± 18.4 | 8.4 ± 29.8 | 0.520 |
Timed Up and Go test result, s | 29.8 ± 20.2 † | 17.8 ± 10.3 | 0.058 |
ACB Group (n = 15) | p-Value, Within-Group Comparison | Placebo Group (n = 16) | p-Value, Within-Group Comparison | p-Value, Between-Group Comparison | |
---|---|---|---|---|---|
NRS score | 0.002 * | 0.253 | |||
Pre-injection | 7.1 ± 1.6 | 7.3 ± 1.2 | 0.800 | ||
Post-injection | 4.9 ± 2.4 | 6.9 ± 1.5 | 0.009 * | ||
WOMAC | 0.002 * | 0.062 | |||
Pre-injection | 54.6 ± 15.3 | 53.7 ± 11.3 | 0.851 | ||
Post-injection | 44.7 ± 19.1 | 49.4 ± 16.4 | 0.467 | ||
Average daily no. of analgesics consumed, n | 0.414 | 0.450 | |||
Pre-injection | 2.4 ± 2.2 | 2.8 ± 2.5 | 0.740 | ||
Post-injection | 2.1 ± 2.3 | 3.0 ± 3.0 | 0.520 | ||
Average daily opioid consumption, mg | 0.157 | 0.715 | |||
Pre-injection | 8.2 ± 18.4 | 8.4 ± 29.8 | 0.520 | ||
Post-injection | 7.0 ± 18.2 | 6.2 ± 17.3 | 0.892 | ||
Timed Up and Go test result, s | 0.064 | 0.898 | |||
Pre-injection | 29.8 ± 20.2 † | 17.1 ± 10.3 | 0.058 | ||
Post-injection | 34.9 ± 47.8 † | 17.7 ± 10.1 | 0.193 |
ACB Group (n = 15) | Placebo Group (n = 16) | p-Value | |
---|---|---|---|
ΔWOMAC_pain | 2.8 ± 2.5 | 0.1 ± 2.7 | 0.012 * |
ΔWOMAC_stiffness | 0.3 ± 1.2 | 0.8 ± 1.6 | 0.369 |
ΔWOMAC_physical function | 6.8 ± 9.2 | 3.4 ± 7.2 | 0.401 |
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Kim, K.-Y.; Huh, Y.-G.; Ma, S.H.; Yoon, J.H.; Jeong, K.-Y.; Park, D.Y.; Yoon, S.-H. Efficacy of Adductor Canal Block on Medial Knee Pain in Patients with Knee Osteoarthritis: A Randomized Single-Blind Placebo-Controlled Study. Int. J. Environ. Res. Public Health 2022, 19, 15419. https://doi.org/10.3390/ijerph192215419
Kim K-Y, Huh Y-G, Ma SH, Yoon JH, Jeong K-Y, Park DY, Yoon S-H. Efficacy of Adductor Canal Block on Medial Knee Pain in Patients with Knee Osteoarthritis: A Randomized Single-Blind Placebo-Controlled Study. International Journal of Environmental Research and Public Health. 2022; 19(22):15419. https://doi.org/10.3390/ijerph192215419
Chicago/Turabian StyleKim, Ki-Yong, Yool-Gang Huh, Sang Hyeok Ma, Jong Hyeon Yoon, Kil-Yong Jeong, Do Young Park, and Seung-Hyun Yoon. 2022. "Efficacy of Adductor Canal Block on Medial Knee Pain in Patients with Knee Osteoarthritis: A Randomized Single-Blind Placebo-Controlled Study" International Journal of Environmental Research and Public Health 19, no. 22: 15419. https://doi.org/10.3390/ijerph192215419