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IJERPH
Volume 19
Issue 4
10.3390/ijerph19042193
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Article
Peer-Review Record

The Influence of Environmental Polycyclic Aromatic Hydrocarbons (PAHs) Exposure on DNA Damage among School Children in Urban Traffic Area, Malaysia

Int. J. Environ. Res. Public Health 2022, 19(4), 2193; https://doi.org/10.3390/ijerph19042193
by Nur Hazirah Hisamuddin 1, Juliana Jalaludin 1,*, Suhaili Abu Bakar 2 and Mohd Talib Latif 3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Reviewer 3: Anonymous
Int. J. Environ. Res. Public Health 2022, 19(4), 2193; https://doi.org/10.3390/ijerph19042193
Submission received: 30 December 2021 / Revised: 11 February 2022 / Accepted: 12 February 2022 / Published: 15 February 2022
(This article belongs to the Special Issue 2nd Edition of Integrated Human Exposure to Air Pollution)

Round 1

Reviewer 1 Report

See the attached document . 

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

This study is valuable in the sense that it provides data in support of the correlation between cancer risk exposure in children and environmental PAH contamination level. The findings of the study are non-surprising and rather expected. A closer proximity of schools to heavy-traffic areas (i.e. higher levels of PAHs released into the environment) reflects an increased health concern.

Some things to keep in mind when revising the manuscript are:

  1. Line 145: Six-point calibration seems to have been performed (rather than five point as mentioned)
  2. Figures 2a and 2b: Please add error bars in order for readers to be able to better appreciate magnitude of differences.
  3. There is no "s" after PAH when used as attribute of a noun, i.e. for example in "PAH samples" (lines 14 and 114); PAH concentrations (line 18); PAH exposure (lines 24, 68, 463, and 525).
  4. Line 34: "humans" (plural)
  5. Line 106: rephrase to "and 228 respondents completed..."
  6. Line 229: rephrase to "Results clearly showed that..."
  7. Line 254: rephrase to "other studies dealing with the school environment..."

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 3 Report

Dear authors:

The paper is well-writing and shows interesting results, although some improvements could be included:

  1. Like PAH and UFP, prolonged exposure to volatile organic compounds (VOCs; e.g. BTEX compounds) also has been related to cell damage. VOCs are usually detected in relatively high concentration (mg/m3) in urban areas [e.g. 10.1016/j.chemosphere.2020.128127]. So, this study could be considered limited or biased by not including VOCs. Please justify
  2. It is suggested that the results and findings of this work be discussed and contrasted with similar studies found in the literature.
  3. All images look fuzzy. Consider the use of high-definition images.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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