Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethical Approval and Study Design
2.1.1. CT
2.1.2. ET
2.2. Participants
2.3. ISF Glucose Concentrations
2.4. Characteristics of Participants
2.5. Blood Markers
2.6. Muscle Stiffness and Fatigue
2.7. Statistical Analyses
3. Results
3.1. Characteristics of Participants
3.2. Comparison of ISF Glucose Concentrations by the OGTT in Two Trials
3.3. Changes in Blood Markers after RVT
3.4. Changes in Muscle Stiffness and Fatigue after RVT
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Zeyda, M.; Stulnig, T.M. Obesity, inflammation, and insulin resistance a mini-review. Gerontology 2009, 55, 379–386. [Google Scholar] [CrossRef]
- Hawley, J.A. Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance. Diabetes Metab. Res. Rev. 2004, 20, 383–393. [Google Scholar] [CrossRef] [PubMed]
- Del Porto, H.C.; Pechak, C.M.; Smith, D.R.; Reed-Jones, R.J. Biomechanical effects of obesity on balance. Int. J. Exerc. Sci. 2012, 5, 301–320. [Google Scholar]
- Orlando, G.; Balducci, S.; Bazzucchi, I.; Pugliese, G.; Sacchetti, M. Muscle fatigability in type 2 diabetes. Diabetes Metab. Res. Rev. 2017, 33, e2821. [Google Scholar] [CrossRef] [PubMed]
- Zago, M.; Capodaglio, P.; Ferrario, C.; Tarabini, M.; Galli, M. Whole-body vibration training in obese subjects: A systematic review. PLoS ONE 2018, 13, e0202866. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Nishihira, Y.; Iwasaki, T.; Hatta, A.; Wasaka, T.; Kaneda, T.; Kuroiwa, K.; Akiyama, S.; Kida, T.; Kim, S. Effect of whole body vibration stimulus and voluntary contraction on motoneuron pool. Adv. Exerc. Sports Physiol. 2002, 8, 83–86. [Google Scholar]
- Rauch, F. Vibration therapy. Dev. Med. Child. Neurol. 2009, 4, 166–168. [Google Scholar] [CrossRef]
- Di Loreto, C.; Ranchelli, A.; Lucidi, P.; Murdolo, G.; Parlanti, N.; De Cicco, A.; Tsarpela, O.; Annino, G.; Bosco, C.; Santeusanio, F.; et al. Effects of whole-body vibration exercise on the endocrine system of healthy men. J. Endocrinol. Investig. 2004, 27, 323–327. [Google Scholar] [CrossRef]
- Del Pozo-Cruz, B.; Alfonso-Rosa, R.M.; Del Pozo-Cruz, J.; Sañudo, B.; Rogers, M.E. Effects of a 12-wk whole-body vibration based intervention to improve type 2 diabetes. Maturitas 2014, 77, 52–58. [Google Scholar] [CrossRef] [Green Version]
- Oh, S.; Shida, T.; Sawai, A.; Maruyama, T.; Eguchi, K.; Isobe, T.; Okamoto, Y.; Someya, N.; Tanaka, K.; Arai, E.; et al. Acceleration training for managing nonalcoholic fatty liver disease: A pilot study. Ther. Clin. Risk. Manag. 2014, 7, 925–936. [Google Scholar] [CrossRef] [Green Version]
- Oh, S.; Oshida, N.; Someya, N.; Maruyama, T.; Isobe, T.; Okamoto, Y.; Kim, T.; Kim, B.; Shoda, J. Whole-body vibration for patients with nonalcoholic fatty liver disease: A 6-month prospective study. Physiol. Rep. 2019, 7, e14062. [Google Scholar] [CrossRef] [Green Version]
- Jayasekara, H.; English, D.R.; Room, R.; MacInnis, R.J. Alcohol consumption over time and risk of death: A systematic review and meta-analysis. Am. J. Epidemiol. 2014, 179, 1049–1059. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sakaguchi, K.; Hirota, Y.; Hashimoto, N.; Ogawa, W.; Sato, T.; Okada, S.; Hagino, K.; Asakura, Y.; Kikkawa, Y.; Kojima, J.; et al. A minimally invasive system for glucose area under the curve measurement using interstitial fluid extraction technology: Evaluation of the accuracy and usefulness with oral glucose tolerance tests in subjects with and without diabetes. Diabetes Technol. Ther. 2012, 14, 485–491. [Google Scholar] [CrossRef]
- Ólafsdóttir, A.F.; Attvall, S.; Sandgren, U.; Dahlqvist, S.; Pivodic, A.; Skrtic, S.; Theodorsson, E.; Lind, M. A Clinical Trial of the Accuracy and Treatment Experience of the Flash Glucose Monitor FreeStyle Libre in Adults with Type 1 Diabetes. Diabetes Technol. Ther. 2017, 19, 164–172. [Google Scholar] [CrossRef] [Green Version]
- Miyawaki, T.; Hirata, M.; Moriyama, K.; Sasaki, Y.; Aono, H.; Saito, N.; Nakao, K. Metabolic syndrome in Japanese diagnosed with visceral fat measurement by computed tomography. Proc. Jpn. Acad. 2005, 81, 471–479. [Google Scholar] [CrossRef] [Green Version]
- Henriksen, A.; Johansson, J.; Hartvigsen, G.; Grimsgaard, S.; Hopstock, L. Measuring Physical Activity Using Triaxial Wrist Worn Polar Activity Trackers: A Systematic Review. Int. J. Exerc. Sci. 2020, 13, 438–454. [Google Scholar] [PubMed]
- Chang, T.T.; Li, Z.; Zhu, Y.C.; Wang, X.Q.; Zhang, Z.J. Effects of Self-Myofascial Release Using a Foam Roller on the Stiffness of the Gastrocnemius-Achilles Tendon Complex and Ankle Dorsiflexion Range of Motion. Front. Physiol. 2021, 17, 12. [Google Scholar] [CrossRef] [PubMed]
- Kim, M.; Seol, J.; Sato, T.; Fukamizu, Y.; Sakurai, T.; Okura, T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients 2022, 14, 755. [Google Scholar] [CrossRef]
- Wolever, T.M.; Jenkins, D.J. The use of the glycemic index in predicting the blood glucose response to mixed meals. Am. J. Clin. Nutr. 1986, 43, 167–172. [Google Scholar] [CrossRef]
- Cardinale, M.; Bosco, C. The use of vibration as an exercise intervention. Exerc. Sport. Sci. Rev. 2003, 31, 3–7. [Google Scholar] [CrossRef]
- Goodyear, L.J.; Hirshman, M.F.; Horton, E.S. Exercise-induced translocation of skeletal muscle glucose transporters. Am. J. Physiol. 1991, 261, e795–e799. [Google Scholar] [CrossRef] [PubMed]
- Gao, J.; Ren, J.; Gulve, E.A.; Holloszy, J.O. Additive effect of contractions and insulin on GLUT-4 translocation into the sarcolemma. J. Appl. Physiol. 1994, 77, 1597–1601. [Google Scholar] [CrossRef]
- Robinson, C.C.; Barreto, R.P.; Sbruzzi, G.; Plentz, R.D. The effects of whole body vibration in patients with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Braz. J. Phys. Ther. 2016, 20, 4–14. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Baum, K.; Votteler, T.; Schiab, J. Efficiency of vibration exercise for glycemic control in type 2 diabetes patients. Int. J. Med. Sci. 2007, 4, 159–163. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Lee, K.; Lee, S.; Song, C. Whole-body vibration training improves balance, muscle strength and glycosylated hemoglobin in elderly patients with diabetic neuropathy. Tohoku J. Exp. Med. 2013, 231, 305–314. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Pessoa, M.F.; De Souza, H.C.M.; Da Silva, A.P.V.; Clemente, R.D.S.; Brandão, D.C.; De Andrade, A.D. Acute Whole Body Vibration Decreases the Glucose Levels in Elderly Diabetic Women. Rehabil. Res. Pract. 2018, 5, 3820615. [Google Scholar] [CrossRef]
- Toloza, F.J.K.; Mantilla-Rivas, J.O.; Pérez-Matos, M.C.; Ricardo-Silgado, M.L.; Morales-Alvarez, M.C.; Pinzón-Cortés, J.A.; Pérez-Mayorga, M.; Arévalo-Garcia, M.L.; Tolosa-González, G.; Mendivil, C.O. Plasma levels of myonectin but not myostatin or fibroblast-derived growth factor 21 are associated with insulin resistance in adult humans without diabetes mellitus. Front. Endocrinol. 2018, 9. [Google Scholar] [CrossRef] [Green Version]
- Kaur, K.K.; Allahbadia, G.; Singh, M. A review of nutrient metabolism in Obesity with special Emphasis on Fatty acid metabolism. BAO J. Food Sci. Technol. 2017, 1, 1–16. [Google Scholar]
- Liu, Q.; Wang, S.; Wei, M.; Huang, X.; Cheng, Y.; Shao, Y.; Xia, P.; Zhong, M.; Liu, S.; Zhang, G.; et al. Improved FGF21 Sensitivity and Restored FGF21 Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Rats After Duodenal-Jejunal Bypass and Sleeve Gastrectomy. Front. Endocrinol. 2019, 30, 566. [Google Scholar] [CrossRef] [Green Version]
- Amor, M.; Itariu, B.K.; Moreno-Viedma, V.; Keindl, M.; Jürets, A.; Prager, G.; Langer, F.; Grablowitz, V.; Zeyda, M.; Stulnig, T.M. Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans. Exp. Clin. Endocrinol. Diabetes 2019, 127, 550–556. [Google Scholar] [CrossRef]
- Shabkhiz, F.; Khalafi, M.; Rosenkranz, S.; Karimi, P.; Moghadami, K. Resistance training attenuates circulating FGF-21 and myostatin and improves insulin resistance in elderly men with and without type 2 diabetes mellitus: A randomised controlled clinical trial. Eur. J. Sport Sci. 2021, 21, 636–645. [Google Scholar] [CrossRef] [PubMed]
- Blanks, A.M.; Rodriguez-Miguelez, P.; Looney, J.; Tucker, M.A.; Jeong, J.H.; Thomas, J.; Blackburn, M.; Stepp, D.W.; Weintraub, N.J.; Harris, R.A. Whole body vibration elicits differential immune and metabolic responses in obese and normal weight individuals. Brain Behav. Immun. 2020, 1, 100011. [Google Scholar] [CrossRef]
- Louis, E.; Raue, U.; Yang, Y.; Jemiolo, B.; Trappe, S. Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle. J. Appl. Physiol. 2007, 103, 1744–1751. [Google Scholar] [CrossRef] [Green Version]
- Mika, A.; Sledzinski, T. Alterations of specific lipid groups in serum of obese humans: A review. Obes. Rev. 2017, 18, 247–272. [Google Scholar] [CrossRef] [PubMed]
- Mester, J.; Kleinöder, H.; Yue, Y. Vibration training: Benefits and risks. J. Biomech. 2006, 39, 1056–1065. [Google Scholar] [CrossRef] [PubMed]
- Behboudi, L.; Azarbayjani, M.A.; Aghaalinejad, H.; Salavati, M. Effects of aerobic exercise and whole body vibration on glycaemia control in type 2 diabetic males. Asian J. Sports 2011, 2, 83–90. [Google Scholar] [CrossRef] [Green Version]
- Hazell, T.J.; Jakobi, J.M.; Kenno, K.A. The effects of whole-body vibration on upper- and lower-body EMG during static and dynamic contractions. Appl. Physiol. Nutr. Metab. 2007, 32, 1156–1163. [Google Scholar] [CrossRef] [Green Version]
- Alentorn-Geli, E.; Padilla, J.; Moras, G.; Haro, C.L.; Fernández-Solà, J. Six weeks of whole-body vibration exercise improves pain and fatigue in women with fibromyalgia. J. Altern. Complement. Med. 2008, 14, 975–981. [Google Scholar] [CrossRef] [Green Version]
- Aminian-Far, A.; Hadian, M.R.; Olyaei, G.; Talebian, S.; Bakhtiary, A.H. Whole-body vibration and the prevention and treatment of delayed-onset muscle soreness. J. Athl. Train. 2011, 46, 43–49. [Google Scholar] [CrossRef] [Green Version]
- Rhea, M.R.; Bunker, D.; Marín, P.J.; Lunt, K. Effect of iTonic whole-body vibration on delayed-onset muscle soreness among untrained individuals. J. Strength Cond. Res. 2009, 23, 1677–1682. [Google Scholar] [CrossRef] [Green Version]
- Sharma, K.S.; Mudgal, S.K.; Thakur, K.; Gaur, R. How to calculate sample size for observational and experimental nursing research studies. Natl. J. Physiol. Pharm. Pharmacol. 2020, 10, 1–8. [Google Scholar] [CrossRef]
Parameter, Unit | |
---|---|
Total participants, n | 31 |
Female, n (%) | 15 (48.4) |
Male, n (%) | 16 (51.6) |
Age, year | 55.6 ± 8.4 |
Smoking, n (%) | 8 (25.8) |
Alcohol intake, n (%) | 22 (71.0) |
Medical history | |
Hypertension, n (%) | 12 (38.7) |
Diabetes, n (%) | 2 (6.5) |
Hyperlipidemia, n (%) | 4 (12.9) |
Knee pain, n (%) | 4 (12.9) |
Anthropometric and body composition | |
Height, cm | 165.9 ± 9.4 |
Weight, kg | 80.1 ± 13.8 |
BMI, kg/m2 | 29.0 ± 3.7 |
Muscle mass, kg | 49.5 ± 11.2 |
Fat mass (male), kg | 25.3 ± 7.6 |
Fat mass (female), kg | 30.3 ± 9.5 |
Risk factor of metabolic syndrome | |
Abdominal obesity, n (%) | 31 (100) |
High blood pressure, n (%) | 22 (71.0) |
High fasting glucose, n (%) | 6 (19.4) |
Low HDL-C, n (%) | 1 (3.2) |
Hypertriglyceridemia, n (%) | 8 (25.8) |
Parameter, Unit | Baseline | After | Δ (%) | p | r |
---|---|---|---|---|---|
Skeletal muscle stiffness, N/m | |||||
Trapezius | 401.8 ± 54.7 | 399.8 ± 64.3 | −0.5 | 0.79 | −0.05 |
Deltoid | 273.5 ± 41.0 | 277.0 ± 42.0 | −1.4 | 0.10 | 0.29 |
Biceps brachii | 246.7 ± 39.2 | 242.0 ± 29.5 | −1.3 | 0.75 | −0.06 |
Rectus femoris | 293.2 ± 27.9 | 294.5 ± 25.1 | +0.6 | 0.41 | 0.15 |
Biceps femoris | 285.0 ± 33.7 | 281.1 ± 31.0 | −1.2 | 0.15 | −0.26 |
Tibialis anterior | 388.6 ± 82.2 | 379.8 ± 70.4 | −1.5 | 0.26 | −0.20 |
Medial gastrocnemius | 271.0 ± 26.2 | 266.2 ± 20.9 | −1.6 | 0.02 | −0.43 |
Body parts of fatigue, Point | |||||
Upper-body part | 5.9 ± 5.5 | 1.8 ± 2.7 | −34.9 | <0.01 | −0.65 |
Lower-body part | 3.9 ± 3.6 | 1.2 ± 2.0 | −41.8 | <0.01 | −0.63 |
Total score of whole-body | 9.8 ± 8.5 | 3.0 ± 4.4 | −42.8 | <0.01 | −0.71 |
Subjective symptoms of fatigue, Point | |||||
Drowsiness | 6.7 ± 2.3 | 5.5 ± 1.5 | −10.7 | <0.01 | −0.51 |
Instability | 5.6 ± 1.9 | 5.1 ± 0.4 | −5.5 | 0.02 | −0.42 |
Uneasiness | 5.8 ± 2.0 | 5.2 ± 0.7 | −5.2 | 0.12 | −0.28 |
Local pain or dullness | 8.8 ± 3.1 | 6.1 ± 1.5 | −24.5 | <0.01 | −0.71 |
Eyestrain | 6.9 ± 2.4 | 5.4 ± 0.9 | −15.9 | <0.01 | −0.64 |
Total score of symptoms fatigue | 33.8 ± 8.9 | 27.4 ± 3.9 | −15.5 | <0.01 | −0.70 |
Muscle damage marker | |||||
Creatine Kinase, U/L | 147.3 ± 146.3 | 146.2 ± 143.8 | −0.3 | 0.21 | −0.2 |
Aspartate transaminase, U/L | 23.5 ± 9.6 | 23.6 ± 9.6 | +0.9 | 1.00 | 0 |
lactate dehydrogenase, U/L | 181.0 ± 31.9 | 179.8 ± 30.9 | −0.5 | 0.19 | −0.24 |
Hs-CRP, mg/dL | 0.0784 ± 0.082 | 0.0780 ± 0.081 | −0.7 | 0.86 | 0 |
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Kim, M.; Zhang, H.; Kim, T.; Mori, Y.; Okura, T.; Tanaka, K.; Isobe, T.; Sakae, T.; Oh, S. Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity. Int. J. Environ. Res. Public Health 2023, 20, 4708. https://doi.org/10.3390/ijerph20064708
Kim M, Zhang H, Kim T, Mori Y, Okura T, Tanaka K, Isobe T, Sakae T, Oh S. Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity. International Journal of Environmental Research and Public Health. 2023; 20(6):4708. https://doi.org/10.3390/ijerph20064708
Chicago/Turabian StyleKim, Mijin, Hanlin Zhang, Taeho Kim, Yutaro Mori, Tomohiro Okura, Kiyoji Tanaka, Tomonori Isobe, Takeji Sakae, and Sechang Oh. 2023. "Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity" International Journal of Environmental Research and Public Health 20, no. 6: 4708. https://doi.org/10.3390/ijerph20064708