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Article

Lymphoepithelioma-Like Carcinoma of the Breast: A Diagnostic and Therapeutic Challenge

1
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON M5G 2M9, Canada
2
University of Toronto, Toronto, ON, Canada
3
Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada
4
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2012, 19(3), 177-183; https://doi.org/10.3747/co.19.926
Submission received: 2 March 2012 / Revised: 4 April 2012 / Accepted: 6 May 2012 / Published: 1 June 2012

Abstract

We present a patient with lymphoepithelioma-like carcinoma (LELC) of the breast whose diagnosis is illustrative of the pathology nuances that must be taken into account to successfully reach correct identification of the disease. We also present an overview of our patient’s proposed treatment in the context of 16 other reported LELC cases. Although LELC cases are rare, a sufficient number have been reported to discern the natural history of this pathologic entity and to undertake a review of those cases and of the application of oncologic first principles in their management. Given the potential for locoregional spread and distant metastases in LELC, adjuvant therapy has a role in the treatment of this entity.
Keywords: lymphoepithelioma-like carcinoma; breast; radiotherapy lymphoepithelioma-like carcinoma; breast; radiotherapy

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MDPI and ACS Style

Dinniwell, R.; Hanna, W.M.; Mashhour, M.; Saad, R.S.; Czarnota, G.J. Lymphoepithelioma-Like Carcinoma of the Breast: A Diagnostic and Therapeutic Challenge. Curr. Oncol. 2012, 19, 177-183. https://doi.org/10.3747/co.19.926

AMA Style

Dinniwell R, Hanna WM, Mashhour M, Saad RS, Czarnota GJ. Lymphoepithelioma-Like Carcinoma of the Breast: A Diagnostic and Therapeutic Challenge. Current Oncology. 2012; 19(3):177-183. https://doi.org/10.3747/co.19.926

Chicago/Turabian Style

Dinniwell, R., W.M. Hanna, M. Mashhour, R.S. Saad, and G.J. Czarnota. 2012. "Lymphoepithelioma-Like Carcinoma of the Breast: A Diagnostic and Therapeutic Challenge" Current Oncology 19, no. 3: 177-183. https://doi.org/10.3747/co.19.926

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