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Current Oncology
Volume 20
Issue 5
10.3747/co.20.1457
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Article

Patterns of Practice in the Prescription of Palliative Radiotherapy for the Treatment of Bone Metastases at the Rapid Response Radiotherapy Program between 2005 and 2012

by
N. Thavarajah
,
L. Zhang
,
K. Wong
,
G. Bedard
,
E. Wong
,
M. Tsao
,
C. Danjoux
,
E. Barnes
,
A. Sahgal
,
K. Dennis
,
L. Holden
,
N. Lauzon
and
E. Chow
*
Rapid Response Radiotherapy Program, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2013, 20(5), 396-405; https://doi.org/10.3747/co.20.1457
Submission received: 3 July 2013 / Revised: 8 August 2013 / Accepted: 12 September 2013 / Published: 1 October 2013

Abstract

Objective: We examined whether patterns of practice in the prescription of palliative radiation therapy for bone metastases had changed over time in the Rapid Response Radiotherapy Program (RRRP). Methods: After reviewing data from August 1, 2005, to April 30, 2012, we analyzed patient demographics, diseases, organizational factors, and possible reasons for the prescription of various radiotherapy fractionation schedules. The chi-square test was used to detect differences in proportions between unordered categorical variables. Univariate logistic regression analysis and the simple Fisher exact test were also used to determine the factors most significant to choice of dose–fractionation schedule. Results: During the study period, 2549 courses of radiation therapy were prescribed. In 65% of cases, a single fraction of radiation therapy was prescribed, and in 35% of cases, multiple fractions were prescribed. A single fraction of radiation therapy was more frequently prescribed when patients were older, had a prior history of radiation, or had a prostate primary, and when the radiation oncologist had qualified before 1990. Conclusions: For patients with bone metastasis, a single fraction of radiation therapy was prescribed with significantly greater frequency.
Keywords: palliative radiation therapy; patterns of practice; bone metastasis; dose fractionation palliative radiation therapy; patterns of practice; bone metastasis; dose fractionation

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MDPI and ACS Style

Thavarajah, N.; Zhang, L.; Wong, K.; Bedard, G.; Wong, E.; Tsao, M.; Danjoux, C.; Barnes, E.; Sahgal, A.; Dennis, K.; et al. Patterns of Practice in the Prescription of Palliative Radiotherapy for the Treatment of Bone Metastases at the Rapid Response Radiotherapy Program between 2005 and 2012. Curr. Oncol. 2013, 20, 396-405. https://doi.org/10.3747/co.20.1457

AMA Style

Thavarajah N, Zhang L, Wong K, Bedard G, Wong E, Tsao M, Danjoux C, Barnes E, Sahgal A, Dennis K, et al. Patterns of Practice in the Prescription of Palliative Radiotherapy for the Treatment of Bone Metastases at the Rapid Response Radiotherapy Program between 2005 and 2012. Current Oncology. 2013; 20(5):396-405. https://doi.org/10.3747/co.20.1457

Chicago/Turabian Style

Thavarajah, N., L. Zhang, K. Wong, G. Bedard, E. Wong, M. Tsao, C. Danjoux, E. Barnes, A. Sahgal, K. Dennis, and et al. 2013. "Patterns of Practice in the Prescription of Palliative Radiotherapy for the Treatment of Bone Metastases at the Rapid Response Radiotherapy Program between 2005 and 2012" Current Oncology 20, no. 5: 396-405. https://doi.org/10.3747/co.20.1457

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