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Current Oncology
Volume 27
Issue s3
10.3747/co.27.7171
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Review

Current Locoregional Therapies and Treatment Strategies in Hepatocellular Carcinoma

by
L. Cardarelli-Leite
1,*,
A. Hadjivassiliou
2,
D. Klass
2,
J. Chung
2,
S. G. F. Ho
2,
H. J. Lim
3,
P. T. W. Kim
4,
A. Mujoomdar
1 and
D. M. Liu
2
1
Department of Medical Imaging, Western University, London, ON, Canada
2
Department of Radiology, University of British Columbia, Vancouver, BC, Canada
3
Department of Medical Oncology, BC Cancer–Vancouver Centre, Vancouver, BC, Canada
4
Department of Surgery, University of British Columbia, Vancouver, BC, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2020, 27(s3), 144-151; https://doi.org/10.3747/co.27.7171
Submission received: 5 August 2020 / Revised: 6 September 2020 / Accepted: 7 October 2020 / Published: 1 November 2020

Abstract

Locoregional therapies (LRTs) play an important role in the treatment of hepatocellular carcinoma (HCC), with the aim of increasing overall survival while preserving liver function. Various forms of LRT are available, and choosing the best one depends on technical aspects, liver morphology, tumour biology, and the patient’s symptoms. The purpose of the present review article is to provide an overview of the current evidence relating to the use of percutaneous ablation, transarterial chemoembolization, and transarterial radioembolization for the curative or palliative treatment of HCC. Special situations are also reviewed, including the combined use of systemic therapy and LRT, indications and techniques for bridging to transplant and downstaging, and the use of LRT to treat patients with HCC and macrovascular invasion.
Keywords: hepatocellular carcinoma; interventional radiology; transarterial radioembolization; chemoembolization; radiofrequency ablation hepatocellular carcinoma; interventional radiology; transarterial radioembolization; chemoembolization; radiofrequency ablation

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MDPI and ACS Style

Cardarelli-Leite, L.; Hadjivassiliou, A.; Klass, D.; Chung, J.; Ho, S.G.F.; Lim, H.J.; Kim, P.T.W.; Mujoomdar, A.; Liu, D.M. Current Locoregional Therapies and Treatment Strategies in Hepatocellular Carcinoma. Curr. Oncol. 2020, 27, 144-151. https://doi.org/10.3747/co.27.7171

AMA Style

Cardarelli-Leite L, Hadjivassiliou A, Klass D, Chung J, Ho SGF, Lim HJ, Kim PTW, Mujoomdar A, Liu DM. Current Locoregional Therapies and Treatment Strategies in Hepatocellular Carcinoma. Current Oncology. 2020; 27(s3):144-151. https://doi.org/10.3747/co.27.7171

Chicago/Turabian Style

Cardarelli-Leite, L., A. Hadjivassiliou, D. Klass, J. Chung, S. G. F. Ho, H. J. Lim, P. T. W. Kim, A. Mujoomdar, and D. M. Liu. 2020. "Current Locoregional Therapies and Treatment Strategies in Hepatocellular Carcinoma" Current Oncology 27, no. s3: 144-151. https://doi.org/10.3747/co.27.7171

APA Style

Cardarelli-Leite, L., Hadjivassiliou, A., Klass, D., Chung, J., Ho, S. G. F., Lim, H. J., Kim, P. T. W., Mujoomdar, A., & Liu, D. M. (2020). Current Locoregional Therapies and Treatment Strategies in Hepatocellular Carcinoma. Current Oncology, 27(s3), 144-151. https://doi.org/10.3747/co.27.7171

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