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Current Oncology
Volume 30
Issue 2
10.3390/curroncol30020140
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Article

Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study

by
Laura Tack
1,2,
Ann-Sophie Maenhoudt
3,
Lore Ketelaars
3,
Jolien De Zutter
3,
Stefanie Pinson
3,
Laura Keunebrock
3,
Lorenz Haaker
1,
Kathleen Deckmyn
1,
Mathilde Gheysen
1,
Cindy Kenis
4,5,
Hans Wildiers
4,
Laurence Depoorter
6,
Pieter-Jan Geerts
7,
Rebecca Chandler
8,
Tom Boterberg
2,
Patricia Schofield
9,
Christopher N. Parris
10 and
Philip R. Debruyne
1,9,10,*
1
Department of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium
2
Department of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium
3
Department of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium
4
Department of General Medical Oncology, University Hospitals Leuven, 3000 Leuven, Belgium
5
Department of Public Health and Primary Care, Academic Centre for Nursing and Midwifery, KU Leuven-University of Leuven, 3000 Leuven, Belgium
6
Department of Geriatrics, General Hospital Groeninge, 8500 Kortrijk, Belgium
7
Department of Psychiatry, General Hospital Groeninge, 8500 Kortrijk, Belgium
8
School of Allied Health, Faculty of Health, Education, Medicine and Social Care, Chelmsford CM1 1SQ, UK
9
School of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth PL4 8AA, UK
10
Medical Technology Research Centre (MTRC), School of Life Sciences, Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2023, 30(2), 1805-1817; https://doi.org/10.3390/curroncol30020140
Submission received: 21 December 2022 / Revised: 13 January 2023 / Accepted: 30 January 2023 / Published: 2 February 2023
(This article belongs to the Section Psychosocial Oncology)
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Abstract

Depression is a common and disabling disorder in later life, particularly among people with poor physical health. There are many screening tools available that can be used to examine depressive symptoms; however, not all of them may be appropriate or accurate for older adults with cancer. This pilot study was designed to test the diagnostic performance of two screening tools and their short versions in a cohort of vulnerable (G8 score ≤ 14/17) older patients with cancer undergoing comprehensive geriatric assessment (CGA). The prospective analysis covered 50 vulnerable patients with cancer aged ≥70 years. The diagnostic performance of the Geriatric Depression Scale (GDS)-15, GDS-4, Patient Health Questionnaire (PHQ)-9 and PHQ-2 was compared to the ‘gold standard’ Structured Clinical Interview for DSM-5 Disorders (SCID-5-S) depression module A. The sensitivity and specificity in detecting depressive symptoms were the highest in the case of PHQ-2, with an area under the receiver operating characteristic curve (AUROC) of 92.7%. The AUROC for the 9-item version, PHQ-9, was 90.2%. For the GDS-15 and GDS-4, the AUROC was only 56.2% and 62.0%, respectively. The SCREEN pilot study illustrates the potential benefit of using a shorter screening tool, PHQ-2, to identify older patients with cancer who would benefit from a more in-depth emotional evaluation as part of a CGA.
Keywords: depression; oncogeriatric; older adults with cancer; Patient Health Questionnaire; Geriatric Depression Scale depression; oncogeriatric; older adults with cancer; Patient Health Questionnaire; Geriatric Depression Scale

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MDPI and ACS Style

Tack, L.; Maenhoudt, A.-S.; Ketelaars, L.; De Zutter, J.; Pinson, S.; Keunebrock, L.; Haaker, L.; Deckmyn, K.; Gheysen, M.; Kenis, C.; et al. Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study. Curr. Oncol. 2023, 30, 1805-1817. https://doi.org/10.3390/curroncol30020140

AMA Style

Tack L, Maenhoudt A-S, Ketelaars L, De Zutter J, Pinson S, Keunebrock L, Haaker L, Deckmyn K, Gheysen M, Kenis C, et al. Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study. Current Oncology. 2023; 30(2):1805-1817. https://doi.org/10.3390/curroncol30020140

Chicago/Turabian Style

Tack, Laura, Ann-Sophie Maenhoudt, Lore Ketelaars, Jolien De Zutter, Stefanie Pinson, Laura Keunebrock, Lorenz Haaker, Kathleen Deckmyn, Mathilde Gheysen, Cindy Kenis, and et al. 2023. "Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study" Current Oncology 30, no. 2: 1805-1817. https://doi.org/10.3390/curroncol30020140

APA Style

Tack, L., Maenhoudt, A.-S., Ketelaars, L., De Zutter, J., Pinson, S., Keunebrock, L., Haaker, L., Deckmyn, K., Gheysen, M., Kenis, C., Wildiers, H., Depoorter, L., Geerts, P.-J., Chandler, R., Boterberg, T., Schofield, P., Parris, C. N., & Debruyne, P. R. (2023). Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study. Current Oncology, 30(2), 1805-1817. https://doi.org/10.3390/curroncol30020140

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