Bactericidal and Biocompatible Properties of Plasma Chemical Oxidized Titanium (TiOB®) with Antimicrobial Surface Functionalization
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Preparation
2.2. Antibacterial Functionalization of TiOB®
2.2.1. TiOB® Gta
2.2.2. TiOB® SiOx Ag
2.2.3. TiOB® Zn
2.3. X-ray Photoelectron Spectroscopy (XPS)
2.4. Experimental Section
2.4.1. Bactericidal Properties of Functionalized TiOB®
2.4.1.1. Agar Diffusion Test
2.4.1.2. Proliferation Test
2.4.2. Biocompatible Properties of Functionalized TiOB®
2.5. Statistics
3. Results
3.1. Surface Characterization by Scanning Electron Microscopy
3.2. XPS Analysis
3.3. Bactericidal Properties of Functionalized TiOB®
3.4. Biocompatible Properties of Functionalized TiOB®
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Group Assignment | Technical Information |
---|---|
TiOB control | Ti6Al4V, PCO (280 V), TiOB surface |
TiOB gentamicin-tannic acid (TiOB gta) | Ti6Al4V, PCO (280 V), TiOB surface, dip coating |
TiOB SiOx Ag | Ti6Al4V, PCO (280 V), TiOB surface, APCVD |
TiOB Zn | Ti6Al4V, 1st PCO (200 V), TiOB surface, 2nd PCO (350 V), Zn electrolyte |
Agar Diffusion Test- - | ||||||||
---|---|---|---|---|---|---|---|---|
Eluates Collecting Time | ||||||||
0 h | 2 h | 4 h | 6 h | 12 h | 24 h | 48 h | ||
TiOB® control | 0 | 0 | 0 | 0 | 0 | 0 | 0 | mean inhibition zones [mm] |
TiOB® gta | 0 | 1.94 | 1.88 | 0.50 | 0.94 | 1.50 | 1.25 | |
TiOB8® SiOx Ag | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
TiOB® Zn | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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Kranz, S.; Guellmar, A.; Voelpel, A.; Lesser, T.; Tonndorf-Martini, S.; Schmidt, J.; Schrader, C.; Faucon, M.; Finger, U.; Pfister, W.; et al. Bactericidal and Biocompatible Properties of Plasma Chemical Oxidized Titanium (TiOB®) with Antimicrobial Surface Functionalization. Materials 2019, 12, 866. https://doi.org/10.3390/ma12060866
Kranz S, Guellmar A, Voelpel A, Lesser T, Tonndorf-Martini S, Schmidt J, Schrader C, Faucon M, Finger U, Pfister W, et al. Bactericidal and Biocompatible Properties of Plasma Chemical Oxidized Titanium (TiOB®) with Antimicrobial Surface Functionalization. Materials. 2019; 12(6):866. https://doi.org/10.3390/ma12060866
Chicago/Turabian StyleKranz, Stefan, André Guellmar, Andrea Voelpel, Tobias Lesser, Silke Tonndorf-Martini, Juergen Schmidt, Christian Schrader, Mathilde Faucon, Ulrich Finger, Wolfgang Pfister, and et al. 2019. "Bactericidal and Biocompatible Properties of Plasma Chemical Oxidized Titanium (TiOB®) with Antimicrobial Surface Functionalization" Materials 12, no. 6: 866. https://doi.org/10.3390/ma12060866