Peer-Review Record
In Vitro Cell Interactions on PVDF Films: Effects of Surface Morphology and Polar Phase Transition
Materials 2021, 14(18), 5232; https://doi.org/10.3390/ma14185232
by
Marco A. Alvarez-Perez 1, Valentina Cirillo 2,†, Maria Giovanna Pastore Carbone 3
, Marianna Pannico 4, Pellegrino Musto 4 and Vincenzo Guarino 2,*
, Marianna Pannico 4, Pellegrino Musto 4 and Vincenzo Guarino 2,*Reviewer 1:
Anonymous
Reviewer 2:
Anonymous
Materials 2021, 14(18), 5232; https://doi.org/10.3390/ma14185232
Submission received: 9 July 2021
/
Revised: 1 September 2021
/
Accepted: 6 September 2021
/
Published: 11 September 2021
(This article belongs to the Special Issue Advances in Biomedical and Biomimetic Materials)
Round 1
Reviewer 1 Report
Comments in the attached file.
Comments for author File: 
Comments.pdf
Author Response
attached find enclosed the answers to the Reviewer 1.
Author Response File: Author Response.pdf
Reviewer 2 Report
This work has a quite poor presentation and logic, however, it can be publishable after a major revision as noted
- The title looks awkward, try a better one.
- This work introduces three parameters: morphology, phase transition, and effects on in vitro cell interactions. The authors study the PVDF morphology at 40 and 80 oC and use these samples in vitro culture. However, the phase has been identified by using/studying DSC and for 80 oC samples. It is not a correct way to determine the phase of the samples using DSC (as shown in Figure 4). The author should provide XRD for the characterization of samples at 40 and 80 oC with both concentrations (5% and 20%) to make it more logical.
- Figure 5. Why 5% PVDF (40 oC and 80 oC) has not been provided in this Figure or event supporting information? In the revised version, please also provide β and γ-phases if the author would like to assign something.
- Scientific explanations have not been done in results and discussion. The authors tend to read the data rather than provide a scientific paper. The author should provide more discussion when presenting the results. Here, I can give an example: why PVDF casting at 80°C with a high concentration of polymer can give a higher brightness in Figure 6C. Please take a look at all Figures and make a suitable discussion.
- Make more detailed captions for each figure.
Author Response
Find enclosed the answers to the comments of Reviewer 2
Author Response File: Author Response.pdf
Round 2
Reviewer 2 Report
Although XRD is a good method to characterize the phase of a material. However, the current limitation in the institute has prevented that characterization. Besides, the authors have given much effort to improve the manuscript, as such I recommend publishing this revised version.
