Optimization of In Situ Indentation Protocol to Map the Mechanical Properties of Articular Cartilage
Abstract
:1. Introduction
2. Materials and Methods
2.1. Sample Collection and Management
2.2. A Priori Estimate of the Articular Cartilage Thickness at the Indentation Point
2.3. Optimization of Grid Spacing
2.4. Effect of Indenter Diameter on Articular Cartilage Response
2.5. Pilot Study on a Human Tibial Plateau
2.6. Data Analysis
3. Results
3.1. A Priori Estimate of the Articular Cartilage Thickness at the Indentation Point
3.2. Optimization of Grid Spacing
3.3. Effect of Indenter Diameter on Articular Cartilage Response
3.4. Pilot Study on a Human Tibial Plateau
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
Appendix B
References
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Berni, M.; Erani, P.; Lopomo, N.F.; Baleani, M. Optimization of In Situ Indentation Protocol to Map the Mechanical Properties of Articular Cartilage. Materials 2022, 15, 6425. https://doi.org/10.3390/ma15186425
Berni M, Erani P, Lopomo NF, Baleani M. Optimization of In Situ Indentation Protocol to Map the Mechanical Properties of Articular Cartilage. Materials. 2022; 15(18):6425. https://doi.org/10.3390/ma15186425
Chicago/Turabian StyleBerni, Matteo, Paolo Erani, Nicola Francesco Lopomo, and Massimiliano Baleani. 2022. "Optimization of In Situ Indentation Protocol to Map the Mechanical Properties of Articular Cartilage" Materials 15, no. 18: 6425. https://doi.org/10.3390/ma15186425