Next Article in Journal
The Effect of Cobalt-Sublattice Disorder on Spin Polarisation in Co2FexMn1−xSi Heusler Alloys
Previous Article in Journal
Materials Best Paper Award 2014
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Materials
Volume 7
Issue 3
10.3390/ma7031455
materials-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure

by
Monika Kremplova
1,
Dana Fialova
1,
Lukas Nejdl
1,
David Hynek
1,2,
Libuse Trnkova
1,2,3,
Jaromir Hubalek
1,2,
Rene Kizek
1,2 and
Vojtech Adam
1,2,*
1
Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, Brno CZ-613 00, Czech Republic
2
Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, Brno CZ-616 00, Czech Republic
3
Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Brno CZ-625 00, Czech Republic
*
Author to whom correspondence should be addressed.
Materials 2014, 7(3), 1455-1472; https://doi.org/10.3390/ma7031455
Submission received: 17 November 2013 / Revised: 16 December 2013 / Accepted: 17 February 2014 / Published: 25 February 2014
(This article belongs to the Section Biomaterials)
Browse Figures
Versions Notes

Abstract

The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical behavior of adenine-containing oligonucleotides before and after their isolation using paramagnetic particles. Two peaks were detected—peak A related to the reduction of adenine base and another peak B involved in the interactions between individual adenine strands and contributes to the formation of various spatial structures. The influence of the number of adenine bases in the strand in the isolation process using paramagnetic particles was investigated too.
Keywords: adenine; adenine interaction; magnetic beads; square wave voltammetry; aptamer; biosensor; nanobiotechnology adenine; adenine interaction; magnetic beads; square wave voltammetry; aptamer; biosensor; nanobiotechnology

Share and Cite

MDPI and ACS Style

Kremplova, M.; Fialova, D.; Nejdl, L.; Hynek, D.; Trnkova, L.; Hubalek, J.; Kizek, R.; Adam, V. Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure. Materials 2014, 7, 1455-1472. https://doi.org/10.3390/ma7031455

AMA Style

Kremplova M, Fialova D, Nejdl L, Hynek D, Trnkova L, Hubalek J, Kizek R, Adam V. Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure. Materials. 2014; 7(3):1455-1472. https://doi.org/10.3390/ma7031455

Chicago/Turabian Style

Kremplova, Monika, Dana Fialova, Lukas Nejdl, David Hynek, Libuse Trnkova, Jaromir Hubalek, Rene Kizek, and Vojtech Adam. 2014. "Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure" Materials 7, no. 3: 1455-1472. https://doi.org/10.3390/ma7031455

APA Style

Kremplova, M., Fialova, D., Nejdl, L., Hynek, D., Trnkova, L., Hubalek, J., Kizek, R., & Adam, V. (2014). Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure. Materials, 7(3), 1455-1472. https://doi.org/10.3390/ma7031455

Article Metrics

Back to TopTop