Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking
Abstract
:1. Introduction
2. UEV Structural Features Regulate Tsg101 Recruitment by Its P(T/S)AP-Binding Partners
3. Small Molecule Inhibition Implicates Non-Covalent Ub-Binding at the Tsg101 β-Hairpin in Trafficking of HIV-1, EBV, and HSV-1/2 Capsid Proteins to the Cell Periphery
4. The Vestigial Active Site Region Participates in Lys63-Linked Di-Ub Binding
5. Prazole Resemblance to Nucleic Acid Bases Suggest the UEV Recognizes RNA
6. Summary and Future Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Strickland, M.; Nyenhuis, D.; Watanabe, S.M.; Tjandra, N.; Carter, C.A. Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking. Viruses 2021, 13, 1147. https://doi.org/10.3390/v13061147
Strickland M, Nyenhuis D, Watanabe SM, Tjandra N, Carter CA. Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking. Viruses. 2021; 13(6):1147. https://doi.org/10.3390/v13061147
Chicago/Turabian StyleStrickland, Madeleine, David Nyenhuis, Susan M. Watanabe, Nico Tjandra, and Carol A. Carter. 2021. "Novel Tsg101 Binding Partners Regulate Viral L Domain Trafficking" Viruses 13, no. 6: 1147. https://doi.org/10.3390/v13061147