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Review

Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis

by
Stephen Sinclair III
,
Sean Shearen
,
Youssef Ghobrial
,
George Trad
,
Syed Abdul Basit
,
David Shih
and
John K. Ryan
*
Comprehensive Digestive Institute of Nevada, Las Vegas, NV 89148, USA
*
Author to whom correspondence should be addressed.
Viruses 2024, 16(10), 1531; https://doi.org/10.3390/v16101531
Submission received: 16 August 2024 / Revised: 19 September 2024 / Accepted: 23 September 2024 / Published: 27 September 2024

Abstract

Hepatitis B and Hepatitis C are viral causes of Hepatitis that lead to significant worldwide mortality and morbidity through the sequelae of fibrosis and hepatocellular carcinoma. In this review, we have summarized recent studies that have examined the effects of antiviral therapy on the regression of fibrosis and the reduction in mortalities associated with the viruses. Antiviral therapy significantly decreases mortality and induces the regression of fibrosis.
Keywords: Hepatitis B; Hepatitis C; HCV; HBV; cirrhosis; fibrosis; decompensated cirrhosis; viral Hepatitis; liver-related mortality; portal hypertension Hepatitis B; Hepatitis C; HCV; HBV; cirrhosis; fibrosis; decompensated cirrhosis; viral Hepatitis; liver-related mortality; portal hypertension

Share and Cite

MDPI and ACS Style

Sinclair, S., III; Shearen, S.; Ghobrial, Y.; Trad, G.; Abdul Basit, S.; Shih, D.; Ryan, J.K. Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis. Viruses 2024, 16, 1531. https://doi.org/10.3390/v16101531

AMA Style

Sinclair S III, Shearen S, Ghobrial Y, Trad G, Abdul Basit S, Shih D, Ryan JK. Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis. Viruses. 2024; 16(10):1531. https://doi.org/10.3390/v16101531

Chicago/Turabian Style

Sinclair, Stephen, III, Sean Shearen, Youssef Ghobrial, George Trad, Syed Abdul Basit, David Shih, and John K. Ryan. 2024. "Review of the Effects of Antiviral Therapy on Hepatitis B/C-Related Mortality and the Regression of Fibrosis" Viruses 16, no. 10: 1531. https://doi.org/10.3390/v16101531

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