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  • Cardiogenetics is published by MDPI from Volume 10 Issue 2 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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30 January 2020

Ranolazine Treatment for Refractory Angina in a Patient with Hutchinson-Gilford Progeria Syndrome and End Stage Aortic Stenosis

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1
Unit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, Naples, Italy
2
Institute of Cardiovascular Sciences, University College of London, UK
*
Author to whom correspondence should be addressed.
Cardiogenetics2019, 9(1), 14-15;https://doi.org/10.4081/cardiogenetics.2019.8609
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Abstract

Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.

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