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Pediatric Reports
Volume 9
Issue 3
10.4081/pr.2017.7305
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Article

The Role of Interleukin-6 in the Early Diagnosis of Sepsis in Premature Infants

by
Mehrdad Mirzarahimi
,
Manouchehr Barak
,
Abdolkarim Eslami
and
Afsaneh Enteshari-Moghaddam
*
Department of Pediatrics, School of Medicine, Ardabil University of Medical Science, Ardabil, Iran
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2017, 9(3), 7305; https://doi.org/10.4081/pr.2017.7305
Submission received: 10 July 2017 / Revised: 22 July 2017 / Accepted: 23 July 2017 / Published: 6 October 2017

Abstract

Septicemia is one of the major causes of mortality and morbidity in newborns. The aim of this study was to investigate the role of interleukin-6 (IL-6) in the early diagnosis of Sepsis in premature newborns. This cross-sectional study was conducted on preterm infants admitted to NICU of Hospital Buali in Ardabil city, Iran. C-reactive protein (CRP), IL-6 and complete blood count tests have been done in baseline, third and seventh day. Collected data analyzed by one-sample t-test, repeated measures and ANOVA in SPSS.21. The mean of IL-6 in the first and third day after hospitalization was significantly more than normal value. The mean of CRP in the third and seventh day after hospitalization significantly more than normal value. We found that increasing in IL-6 level can occur earlier than CRP and it can be used as a good index in early sepsis diagnosis compare than CRP.
Keywords: Neonatal Sepsis; Premature newborns; Interleukin-6; CRP Neonatal Sepsis; Premature newborns; Interleukin-6; CRP

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MDPI and ACS Style

Mirzarahimi, M.; Barak, M.; Eslami, A.; Enteshari-Moghaddam, A. The Role of Interleukin-6 in the Early Diagnosis of Sepsis in Premature Infants. Pediatr. Rep. 2017, 9, 7305. https://doi.org/10.4081/pr.2017.7305

AMA Style

Mirzarahimi M, Barak M, Eslami A, Enteshari-Moghaddam A. The Role of Interleukin-6 in the Early Diagnosis of Sepsis in Premature Infants. Pediatric Reports. 2017; 9(3):7305. https://doi.org/10.4081/pr.2017.7305

Chicago/Turabian Style

Mirzarahimi, Mehrdad, Manouchehr Barak, Abdolkarim Eslami, and Afsaneh Enteshari-Moghaddam. 2017. "The Role of Interleukin-6 in the Early Diagnosis of Sepsis in Premature Infants" Pediatric Reports 9, no. 3: 7305. https://doi.org/10.4081/pr.2017.7305

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