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Hematology Reports
Volume 11
Issue 3
10.4081/hr.2019.7056
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Article

Increased Platelets Count in HIV-1 Uninfected Infants Born from HIV-1 Infected Mothers

by
Anicet Christel Maloupazoa Siawaya
1,
Amandine Mveang-Nzoghe
1,
Chérone Nancy Mbani Mpega
2,
Marielle Leboueny
1,
Ofilia Mvoundza Ndjindji
1,
Armel Mintsa Ndong
3,
Paulin N. Essone
1,4 and
Joel Fleury Djoba Siawaya
1,*
1
Unités de Recherche et de Diagnostics Spécialisés, Laboratoire National de Santé Publique, Libreville BP 10736, Gabon
2
Département de Chimie, Faculté des Sciences, Université des Sciences et Techniques de Masuku, Franceville BP 901, Gabon
3
Unité de Virologie, Laboratoire National de Santé Publique, Libreville BP 10736, Gabon
4
Division of Immunology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Science, University of Cape Town, Cape Town 7700, South Africa
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2019, 11(3), 7056; https://doi.org/10.4081/hr.2019.7056
Submission received: 20 January 2017 / Revised: 5 June 2017 / Accepted: 6 June 2017 / Published: 27 September 2019

Abstract

HIV-exposed uninfected infants (HEU) represent a growing population in developing countries including Gabon. Several studies have shown the vulnerability of these infants toward infectious diseases. The aim of the study was to contribute to the global effort to understand how HIVexposure or anti retroviral therapy affects infants’ blood elements. We assessed HEU infants’ complete blood count using a blood analyzer instrument. Our investigations showed that among the observed clinically relevant hematological abnormalities events, thrombocytosis was the most prevalent clinically relevant hematological abnormality associated with HEU infants’. We showed that HEU infants had significantly higher platelets count than HUinfants. Therefore, higher level of platelets seems to characterize HEU infants when compared to HU infants.
Keywords: HIV-exposed; platelets; blood cells HIV-exposed; platelets; blood cells

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MDPI and ACS Style

Siawaya, A.C.M.; Mveang-Nzoghe, A.; Mpega, C.N.M.; Leboueny, M.; Ndjindji, O.M.; Ndong, A.M.; Essone, P.N.; Siawaya, J.F.D. Increased Platelets Count in HIV-1 Uninfected Infants Born from HIV-1 Infected Mothers. Hematol. Rep. 2019, 11, 7056. https://doi.org/10.4081/hr.2019.7056

AMA Style

Siawaya ACM, Mveang-Nzoghe A, Mpega CNM, Leboueny M, Ndjindji OM, Ndong AM, Essone PN, Siawaya JFD. Increased Platelets Count in HIV-1 Uninfected Infants Born from HIV-1 Infected Mothers. Hematology Reports. 2019; 11(3):7056. https://doi.org/10.4081/hr.2019.7056

Chicago/Turabian Style

Siawaya, Anicet Christel Maloupazoa, Amandine Mveang-Nzoghe, Chérone Nancy Mbani Mpega, Marielle Leboueny, Ofilia Mvoundza Ndjindji, Armel Mintsa Ndong, Paulin N. Essone, and Joel Fleury Djoba Siawaya. 2019. "Increased Platelets Count in HIV-1 Uninfected Infants Born from HIV-1 Infected Mothers" Hematology Reports 11, no. 3: 7056. https://doi.org/10.4081/hr.2019.7056

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