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Open AccessArticle
Nurse-Driven Interventions Reduce Central Line-Associated Bloodstream Infection Close to Zero in One Pediatric Oncologic Facility: A Single-Center Retrospective Observational Study
by
Federico Turoldo
Federico Turoldo 1,
Antonella Longo
Antonella Longo 2,
Mariavittoria Sala
Mariavittoria Sala 3,
Denis Valentini
Denis Valentini 4,
Nicole De Vita
Nicole De Vita 2,
Sara Toniutti
Sara Toniutti 2,
Loredana Zuppel
Loredana Zuppel 2 and
Natalia Maximova
Natalia Maximova 2,*
1
Department of Medicine, Surgery and Health Sciences, Hygiene and Preventive Medicine, University of Trieste, Strada di Fiume 447, 34149 Trieste, Italy
2
Department of Pediatrics, Institute for Maternal and Child Health—IRCCS “Burlo Garofolo”, Via dell’Istria 65/1, 34137 Trieste, Italy
3
Department of Public Health and Pediatric Sciences, University of Turin, 10136 Turin, Italy
4
Department of Emergency Medicine, Hospital of Cattinara, Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI), Strada di Fiume 447, 34149 Trieste, Italy
*
Author to whom correspondence should be addressed.
Nurs. Rep. 2024, 14(4), 2668-2679; https://doi.org/10.3390/nursrep14040197 (registering DOI)
Submission received: 28 July 2024
/
Revised: 24 September 2024
/
Accepted: 25 September 2024
/
Published: 26 September 2024
Abstract
Background: Central line-associated bloodstream infections (CLABSIs) are critical infectious complications among pediatric hematology-oncology patients, and the management of central venous catheters (CVCs) by healthcare personnel can significantly influence the incidence of these infections. This study evaluates the impact of nurse-led changes in CVC management on the incidence of CLABSIs. Methods: This single-center, retrospective observational study was conducted at an urban, tertiary referral, and academic center serving pediatric patients. Results: The study cohort comprised 239 patients and 323 CVCs seen between 2012 and 2022. CLABSI was defined according to the Centers for Disease Control and Prevention definitions. Oncology nurse leaders developed CVC-specific educational modules for CLABSI prevention. All the relevant information during the CVC maintenance period was noted in the patient’s CVC logbook. A total of 24 (7%) cases of confirmed CLABSI were identified. The incidence of CVC-related infections was 0.32 cases per 1000 catheter days (95%CI: 0.19–0.45). The incidence decreased by 40% between the first and second three-year study period. Documented exit-site infection was reported in 32 (10%) cases. The correlation between exit-site infection and CLABSI was found in 9 (28%) cases. Our CVC-related infection rates are significantly lower than the incidence reported by the Italian Association of Pediatric Hematology and Oncology, which settles at 3–5 cases per 1000 catheter days. Conclusions: Our data confirm the effectiveness of local CVC management guidelines in preventing CVC-related infectious complications.
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MDPI and ACS Style
Turoldo, F.; Longo, A.; Sala, M.; Valentini, D.; De Vita, N.; Toniutti, S.; Zuppel, L.; Maximova, N.
Nurse-Driven Interventions Reduce Central Line-Associated Bloodstream Infection Close to Zero in One Pediatric Oncologic Facility: A Single-Center Retrospective Observational Study. Nurs. Rep. 2024, 14, 2668-2679.
https://doi.org/10.3390/nursrep14040197
AMA Style
Turoldo F, Longo A, Sala M, Valentini D, De Vita N, Toniutti S, Zuppel L, Maximova N.
Nurse-Driven Interventions Reduce Central Line-Associated Bloodstream Infection Close to Zero in One Pediatric Oncologic Facility: A Single-Center Retrospective Observational Study. Nursing Reports. 2024; 14(4):2668-2679.
https://doi.org/10.3390/nursrep14040197
Chicago/Turabian Style
Turoldo, Federico, Antonella Longo, Mariavittoria Sala, Denis Valentini, Nicole De Vita, Sara Toniutti, Loredana Zuppel, and Natalia Maximova.
2024. "Nurse-Driven Interventions Reduce Central Line-Associated Bloodstream Infection Close to Zero in One Pediatric Oncologic Facility: A Single-Center Retrospective Observational Study" Nursing Reports 14, no. 4: 2668-2679.
https://doi.org/10.3390/nursrep14040197
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