The Role of Technology in the Digital Economy’s Sustainable Development of Hainan Free Trade Port and Genetic Testing: Cloud Computing and Digital Law

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

Introduction

-       Sets the wider context and the debates that the research is contributing to

-       Explains the relevance of the issue to people outside the region covered

-       Makes a clear claim for novelty and relevance

-       Contains a clear research question

-       Explains what data has been gathered

-       Sets out a flavor of the findings

 

Literature Review

-       Highlights the main field of literature to address the research question

-       Identifies a tension in existing understandings that the research will attempt to resolve

-       Sets out a limited number of key concepts that are used to interpret the data

-       Presents a clear evidentiary framework, setting out how data can be analysed

 

Methodology

-       Sets out precisely what evidence has been gathered and how

-       Gives detail about the methods used and justifies this choice

-       Provides information on the context of the region or regions covered in the paper

 

Discussion

-     Makes claims about how the data can be interpreted using the analytic framework

-     Uses the framework to argue that the situation is an example of a larger category

-     Uses that diagnosis to indicate which aspect of the tension is most pertinent (‘analysis’)

-     Explains how widely the findings can be generalized

-     Explains what the relevance of these findings are for policy-makers and/ or practitioners

Comments on the Quality of English Language

No comment

Author Response

Reviewer #1:

Response to reviewers’ comments, also find the PDF enclosed 

(Manuscript Ref: sustainability-3074310)

The authors gratefully thank the reviewers for their comments and suggestions. We appreciate the reviewer’s comments and advice to improve the quality of our manuscript. We have enclosed the revised manuscript wherein we have addressed all the comments point by point and revised the manuscript accordingly. The major comments are addressed below. All the changes made in the manuscript were highlighted in yellow color

 

Reviewer comment# 1.

 

-       Sets the wider context and the debates that the research is contributing to

Answer: Lines 531 to 532, Debates based on Uniform legislation overseeing information collectors' collection, use, and retention of personal data are under E.U. jurisdiction.

-       Explains the relevance of the issue to people outside the region covered

Answer: Lines 99 to 104, In a time where data-centric decision-making is the norm, privacy policies enable people to make educated decisions regarding the management of their data. A complex web of legal requirements, such as the California Consumer Privacy Act (CCPA) and the General Data Protection Regulation (GDPR), influences these decisions. Organizations must ensure that their policies comply with these rules to reduce potential legal risks and safeguard the data rights of persons.

-       Makes a clear claim for novelty and relevance

Answer: Lines 205 to 209, A wealth of research demonstrates that to protect user data, reduce risks, and guarantee regulatory compliance, clear privacy policies and practices are essential. Academics emphasize how difficult it is to strike a compromise between the necessity to protect sensitive data and the affordability and convenience of cloud services.

-       Contains a clear research question

Answer: Lines 21 to 22, how genetic data can be used to provide individualized economic outcomes, and the roles that artificial intelligence and privacy play in these intertwined domains.

-       Explains what data has been gathered

Answer: Lines 294 to 301, Data was gathered from our research review article from a range of research sources with the primary goal of investigating the interconnected patterns in law. It was accomplished by a review of academic papers published in esteemed legal journals, including the International Journal of Law and Information Technology, Yale Law Journal, databases, official websites, WHO, Publishers, and books from 2010 to 2023, and Harvard Law Review. Furthermore, documents released by credible organizations such as the World Intellectual Property Organization (WIPO), the International Data Corporation (I.D.C.), and the European Commission can offer insightful information about the legal aspects of the digital economy and cloud-based genetic testing.

-       Sets out a flavor of the findings

Answer: Lines 590 to 602, Concerns regarding data security and privacy have been brought up by the economy's fast digitization, especially in light of genetic testing and cloud computing in the healthcare industry. To safeguard individual rights and facilitate the advantages of digital health technologies, strong regulatory frameworks are required. Careful management of the shift to a digital economy is necessary to guarantee fair access and stop socioeconomic gaps from growing. To empower marginalized communities to engage in the digital economy and close the digital gap, strategies are needed. Navigating the complex difficulties at the convergence of digital health, digital economy, and emerging technologies like cloud computing and genetic testing requires interdisciplinary collaboration between policymakers, technologists, healthcare practitioners, and legal experts.  Achieving sustainable development in the digital economy necessitates striking a balance between social inclusion, environmental sustainability, and economic growth. Green digital solutions should be promoted, and policies and programs should address how digital technologies affect the environment. The legal and regulatory environment about emerging technologies like cloud computing and genetic testing, as well as the digital economy and health, is changing quickly. Legal frameworks must be reviewed and updated often to ensure they remain current with technology and adhere to sustainability and public welfare.

 

Response to Reviewer: Thank you so much for the reviewer’s kindness in improving our manuscript. We greatly appreciate the time and effort the reviewer spent providing valuable comments on our current research. We have revised the manuscript according to their scholarly suggestions. The revised version is highlighted in yellow above.

  

Reviewer comment# 2. Literature Review

 

-       Highlights the main field of literature to address the research question

Answer: Lines 313 to 315, What legal concerns about data security, privacy, and ethical use of personal information should Web 2.0 environment fosterers, legislators, and regulators about digital health technologies like cloud computing and genetic testing?

-       Identifies a tension in existing understandings that the research will attempt to resolve

Answer: Lines 355 to 358, The goal of the research is to report the ethical, legal, and sustainability issues while resolving the conflict between utilizing the advantages of the digital economy, digital health, and cloud computing.

-       Sets out a limited number of key concepts that are used to interpret the data

Answer: Lines 580 to 584, The E.U. has greatly influenced talks on the global regulatory environment and cloud regulation in particular. As a result, the UK, Germany, France, Italy, and Ireland are among the countries that have passed Internet and privacy regulations based on the concepts and institutional frameworks of European legislation.

-       Presents a clear evidentiary framework, setting out how data can be analyzed

Answer: Lines 453 to 473, The U.S.A. oversees a patchwork of laws, including the CLOUD Act and state-level privacy protections, to address issues with cross-border data access and privacy. While creating its national cybersecurity strategies and healthcare reforms, the U.K. is taking E.U. directives like GDPR into consideration. Through proposed acts like D.S.A. and D.M.A. and unified standards like GDPR, the E.U. is leading the way in creating harmonized standards for digital services, genetic testing, and data protection. These legislative contexts reflect shifting societal demands and technological surroundings, which in turn show different priorities and methods. The legal systems in those countries handle the complicated problems of genetics, technology, privacy, and healthcare through a range of strategies and focal points. China's legislative policy takes a proactive approach to data protection, as evidenced by its strict cybersecurity policies and regulations, by creating comprehensive rules for cloud computing, with a focus on interoperability, security, and regulatory compliance among service providers.

Response to Reviewer: Thank you, reviewer, for raising this concern. In the revised manuscript, we have included key concepts to identify, interpret, and analyze in the literature review. The revised version of the manuscript is highlighted in yellow above. Once again, thank you so much, reviewer.

 

Reviewer comment# 3. Methodology

 

-       Sets out precisely what evidence has been gathered and how

Answer: Lines 465 to 466, highlight the specific problems that competition law must solve for each of these categories, and market power has to be defined more precisely in the context of digital platforms, demands the study of cross-market foreclosure tactics in the digital economy, as well as distinct Commission guidelines for evaluating market dominance in digital platforms.

-       Gives detail about the methods used and justifies this choice

Answer: Lines 305 to 309, The study investigates the moral ramifications of cloud-based genetic data ownership, access, and use. Evaluating the encryption standards and security measures in place in cloud computing for genetic data is essential to guarantee compliance and reduce the danger of data breaches or illegal access and research methods.

-       Provides information on the context of the region or regions covered in the paper

Answer: Lines 640 to 643, The possibility of regional or cultural variances in the application and effects of genetic testing, digital technology, and sustainable development programs is another drawback. Subsequent investigations may go deeper into these contextual elements, possibly retaining cross-cultural analysis.

Response to Reviewer: Thank you for your kind suggestion to include a research methodology that justifies the choice and context of the region. In the revised manuscript, we have also included a future strategy. The revised version of the manuscript is highlighted in yellow above.

Reviewer comment# 4. Discussion

-     Makes claims about how the data can be interpreted using the analytic framework

Answer: Lines 79 to 83, The Web 2.0 era has seen the emergence of platform-driven business models, where organizations utilize user data and network effects to foster innovation and generate revenue. This data-centric strategy has revolutionized how businesses perceive and connect with their target audiences, creating opportunities for tailored marketing, personalized offerings, and data-driven decision-making.

-     Uses the framework to argue that the situation is an example of a larger category

Answer: Lines 347 to 350, The research delves into investigating workable legal remedies and developing policy suggestions to address the recognized legal obstacles and moral dilemmas that emerge in this situation.

-     Uses that diagnosis to indicate which aspect of the tension is most pertinent (‘analysis’)

Answer: Lines 196 to 199, It has a well-established role in risk assessment, individualized treatment, and early diagnosis. It demonstrates the growing significance of genetic testing in the healthcare sector and the need for ethical considerations to support its responsible usage and sustainable growth.

-     Explains how widely the findings can be generalized

Answer: Lines 563 to 569, Medical data in general and genetic data in particular, are often considered sensitive data that require stringent legal protections. As we've seen in our discussion of permission, data protection and privacy laws are crucial to preserving the confidentiality of personal files containing genetic information. For example, records kept by employers and insurers.

-     Explains what the relevance of these findings are for policy-makers and/ or practitioners

Answer: Lines 120 to 124, To develop best practices, standard industry stakeholders, legal experts, and policymakers must work together and monitor the legal framework, improve data protection measures, and provide more evident consent processes.

Response to Reviewer: Thank you so much to the reviewer for raising this discussion about the analytic framework, including the situation, diagnosis, and policy-making. In the revised manuscript, we have followed the reviewer's guidance and suggestions. The revised version of the manuscript is provided in yellow color above.

  

Special Appreciate to the Reviewer: 1

We all, the authors, are deeply grateful to the reviewers for their time and effort, we express our sincere gratitude to the reviewers for their thoughtful suggestions, which have contributed to the improvement of our manuscript, and many thanks.

 

 

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

The topic of the paper is very wide and the introduction does not spot a particular aspect about this topic. The major issues are:

- In the introduction the novelty proposed by the paper is not specified , please highlight this aspect;

- In the introduction, you did not highlight what is the research gap filled by your study with respect to literature;

- The following part of the paper seems to be a review paper that does not focus on a particular aspect of this wide topic; so please focus your attention to some specific argument;

- The results that you have got by your study are not specified , so what is the final results obtained with respect to referenced papers ?

- The discussion of results is not adequate for a scientific paper, so it is too generic and does not give a particultar point of reflection to the reader.

- Please improve the Conclusion with a more detailed discussion about the obtained results.

Comments on the Quality of English Language

English is understandable.

Author Response

Reviewer #2:

In response to reviewers’ comments, also find pdf enclosed with Table and Figure.

(Manuscript Ref: sustainability-3074310)

The authors gratefully thank the reviewers for their comments and suggestions. We appreciate the reviewer’s comments and advice to improve the quality of our manuscript. We have enclosed the revised manuscript wherein we have addressed all the comments point by point and revised the manuscript accordingly. The major comments are addressed below. All the changes made in the manuscript were highlighted in yellow color

 

Reviewer #2: The topic of the paper is very wide and the introduction does not spot a particular aspect about this topic. The major issues are:

 

Response: Thank you so much, respected reviewer, for your observations and feedback on our paper. We appreciate your recognition that the introduction and the scope of the topic do not seem to focus on a specific aspect of the wider subject matter, which you have identified as a major issue, and we try to revisit them according reviewer’s scholarly suggestion and remarks.   

 

Revised the Topic in the Manuscript’s Maine Document and Below: Thanks for the corrected

“The Role of Technology in the Digital Economy's Sustainable Development of Hainan Free Trade Zone and Genetic Testing: Cloud Computing and Digital Law”

 

 

 

Reviewer comment#1: - In the introduction the novelty proposed by the paper is not specified , please highlight this aspect;

Response to Reviewer: Thank you, reviewer, for raising this concern, in the revised manuscript we have included the practical importance of novelty, trade, genetic testing, cloud computing, legal issues, and technologies in the introduction, believe that this updated introduction more accurately conveys the paper's precise focus and goals. We are very grateful for the reviewer's effort to all corrections have been revised part of the introduction is given below and added to the Maine document:

In addition, the core of the Web 2.0 landscape is the emphasis on user engagement and collaboration. Presently, platforms and tools actively promote user participation, sharing, and interaction with content rather than passive consumption. The digital economy and the sustainable development of the Hainan Free Trade Port (HFTP) is significantly shaped by technologies, as demonstrated by the strategic ambition of the Chinese government to create a hub for sustainable economic development and international trade [1]. It explores how numerous facets of the port's development and operations are impacted by cutting-edge technology like cloud computing, Web 2.0 platforms, and genetic testing. HFTP offers new potential to develop its biotechnology and medical sectors, thanks to the revolution in customized medicine and healthcare brought about by genetic testing [2]. The widespread adoption of Web 2.0 technology has also made it easier for people to collaborate and communicate across borders, which has aided in the port's incorporation into international value chains. Also examines the legal and regulatory issues raised by these technological developments, emphasizing the necessity of contemporary legal agendas to guarantee the ethical and responsible use of technologies. It also aims to offer insightful information to researchers, business executives, and policymakers who are interested in leveraging technology to promote sustainable economic growth in the digital era and protect the privacy of genetic testing under digital law [3].

 

The special economic zone has aggressively pushed to develop genetic testing technology as a pioneer zone for digital technology and a testing ground for institutional innovation, intending to leverage the "spark" of regional legislation to start a "wildfire" for global genetic technology and digital development [4].

 

The Web 2.0 era has seen the emergence of platform-driven business models, where organizations utilize user data and network effects to foster innovation and generate revenue. This data-centric strategy has revolutionized how businesses perceive and connect with their target audiences, creating opportunities for tailored marketing, personalized offerings, and data-driven decision-making.

 

In a time where data-centric decision-making is the norm, privacy policies enable people to make educated decisions regarding the management of their data. A complex web of legal requirements, such as the California Consumer Privacy Act (CCPA) and the General Data Protection Regulation (GDPR), influences these decisions. Organizations must ensure that their policies comply with these rules to reduce potential legal risks and safeguard the data rights of persons.

 

To develop best practices, standard industry stakeholders, legal experts, and policymakers must work together and monitor the legal context, improve data protection measures, and provide more evident consent processes. Cloud computing, genetic testing, and the digital economy form a dynamic nexus with significant societal ramifications.

 

 

Reviewer comment#2: - In the introduction, you did not highlight what is the research gap filled by your study with respect to literature.

Response to Reviewer: Thank you, once again, reviewer, you raised the most important question about the research gap, according to your suggestion and scholarly investigation, we have revised the gap in our study literature is given below, and added it to the Maine document:

Although the significance of technologies in the digital economy and sustainable development has been studied in the literature review and legal issues, little research has been done to specifically express, and help how these aspects intersect at the Hainan Free Trade Port. By examining how cutting-edge technologies like cloud computing, Web 2.0, and genetic testing affect the long-term development of the (HFTP), this study seeks to close this gap and digital law. Together with examining the specific policy environment and development objectives of the port, it will also look at the legal and regulatory bases required to secure the proper use of these technologies in the present and future [5].

 

Reviewer comment#3: - The following part of the paper seems to be a review paper that does not focus on a particular aspect of this wide topic; so please focus your attention to some specific argument;

Response to Reviewer: Thank you for the reviewer's kind suggestion to focus on a particular aspect of the topic and provide a specific argument. After the reviewer's advice and guidance, we have revised the manuscript to add a figure and a table to better illustrate our study's argument and improve the presentation for the readers. We are grateful for the reviewer's effort and support in helping us make this an excellent work. The revisions have significantly improved the quality of the manuscript, and we appreciate the reviewer's time and expertise in providing constructive feedback the revised manuscript is given below:

According to the A.P.A., privacy is the ability to limit who can enter one's personal space, both physically and psychologically. This control includes controlling outgoing communication, including the volume and type of personal information released, and controlling incoming information through physical barriers like doors and partitions [6]. The condition of restricted access to personal data is known as "informational privacy (Figure 1)". A breach of privacy occurs whenever someone's private information is made available to another party, either by reading, listening, or any other way. It's like getting an unexpected look at one's "virtual self." The idea of informational privacy is dynamic; very few people can exercise total control all the time. Cloud providers are required to protect data privacy and people's right to control how their personal information is collected and used. Blockchain technology develops and spreads, and protecting information privacy gets more difficult because of the increased amount of data being collected and shared [7]. The possibility that cloud computing organizations may unintentionally process personal data without awareness is known as the "cloud of unknowing."

 

Figure 1. Journal of Advanced Engineering Technologies and Sciences on a Global Scale

 

Table 4. The model presents basic information below

Reviewer comment#4: -The results that you have got by your study are not specified , so what is the final results obtained with respect to referenced papers ?

Response to Reviewer: Thank you so much for your interest in the results of our research. We have included the analysis, discussion, limitations, conclusions, and future research directions as a result in the revised manuscript. Once again thanks for your kindness and time.

 

Reviewer comment#5: - The discussion of results is not adequate for a scientific paper, so it is too generic and does not give a particultar point of reflection to the reader.

Response to Reviewer:

Thank you for your considerate comments and suggestions for improving our manuscript. We have carefully reviewed your comments for discussion and have revised the document accordingly. The updated manuscript incorporates the changes you recommended, we appreciate your time and expertise in helping us strengthen our work. Your guidance has been invaluable in enhancing the quality and clarity of our research, the revised manuscript is given below:

China has been actively pushing digital technology development to get closer to global advanced technology development and reform. Furthermore, a positive trend has emerged since 2013, when a series of free trade ports and pilot zones were established, leading the way in high-tech. Hainan Free Trade Port is one of them; it encourages the deep integration of genetic technology research and the innovation chain, with a focus on scientific and technical innovation. The impending complete island closure and the implementation of the Regional Comprehensive Economic Partnership (RCEP) would create favorable circumstances for enhancing Hainan's degree of openness and encouraging the incorporation of genetic technology that meets international standards [8].

China's stringent regulations on genetic testing, which are detailed in the 2019 Regulation on the Management of Human Genetic Resources, prioritize the privacy of genetic data strict authorization for collection and distribution [9]. The transformation that the World Wide Web has experienced over the last twenty years has been significant, shifting from a static source of information to a more interactive and user-focused environment known as Web 2.0. This evolution, initiated in the early 2000s, has had a profound impact on how individuals, businesses, and communities interact with online content and services.

From the standpoint of sustainable development, the special economic zones' cutting-edge core technologies, healthy ecological surroundings, dynamic economic activity, and stable social order offer a strong basis for drawing in investment and boosting exports. The special economic zones stand out among them in that they highlight the enormous potential that technology innovation offers for economic growth. Dubai Free Zone, for instance, is dedicated to building a competitive knowledge-based economy [10].

Reviewer comment#6: - Please improve the Conclusion with a more detailed discussion about the obtained results.

Response to Reviewer: Thank you so much for your kind and scholarly suggestions to improve the manuscript. We have carefully incorporated the comment you provided, particularly regarding the need for a more detailed discussion in the conclusion section. which has been added in the revised version of the manuscript is given below.

Since the start of Web 2.0, the digital world has experienced unprecedented growth and sustainable development, enabling people, businesses, and communities to use digital tools for the benefit of the environment, society, economy, and cloud computing. These conditions present noteworthy opportunities for fostering long-term development. The Hainan Free Trade Zone's use of genetic testing and cloud computing technologies has the potential to transform scientific research, healthcare, and digital law. A favorable atmosphere for ground-breaking discoveries and individualized medical treatments is created by the availability of sophisticated genetic testing services and the zone's emphasis on scientific and technological innovation. Moreover, Hainan should have even more opportunity to raise its degree of openness and integration with international high-tech norms with the upcoming closure of the entire island and the execution of the Regional Comprehensive Economic Partnership (RCEP) agreement with overseas. The region's standing as a pioneer in genetic technology research and the digital economy would be further strengthened by this. All things considered, the results of this research highlight how technology, especially Web 2.0 and the digital economy, is transforming fields like genetic testing and the sustainable growth of the Hainan Free Trade Zone. The region's future and its global significance are greatly promising due to the synergistic interaction between scientific advancement, economic liberalization, and technological innovation. In direct, the study has shown the enormous potential that digital technologies and the digital economy, especially in the rapidly evolving fields of genetic testing and digital health, have to support sustainable development.

 

Special Appreciate to the Reviewer: 2

We all, the authors, are deeply grateful to the reviewers for their time and effort, we express our sincere gratitude to the reviewers for their thoughtful suggestions, which have contributed to the improvement of our manuscript, and many thanks.

 

References

 

1. Qi, F.; Wu, Y.; Wang, J.; Wang, Q. China’s Hainan Free Trade Port: Medical Laws and Policy Reform. Front. Public Health 2021, 9, doi:10.3389/fpubh.2021.764977.
2. Hainan Allows Import of Urgently Needed Drugs and Medical Devices Available online: https://www.china-briefing.com/news/hainan-updates-policy-on-allowing-import-of-urgently-needed-drugs-and-medical-devices/ (accessed on 4 July 2024).
3. Costello, R.Á. Genetic Data and the Right to Privacy: Towards a Relational Theory of Privacy? Human Rights Law Review 2022, 22, ngab031, doi:10.1093/hrlr/ngab031.
4. Wildy & Sons Ltd — The World’s Legal Bookshop Search Results for Isbn: “9781032140254” Available online: https://www.wildy.com/isbn/9781032140254/freeports-and-free-zones-operations-and-regulation-in-the-global-economy-informa-law-from-routledge (accessed on 4 July 2024).
5. Xiu, C.; Li, T. Construction of the Hainan Free Trade Port from the Perspective of Regional Cultural Development. Front. Earth Sci. 2023, 10, doi:10.3389/feart.2022.1032953.
6. Li, H.; Yang, C.; Liu, J. A Novel Security Media Cloud Framework. Computers & Electrical Engineering 2019, 74, 605–615, doi:10.1016/j.compeleceng.2018.07.022.
7. Otieno, M. Techniques and Protocols for Enhancing Data Privacy in Cloud Computing: A Review. World Journal of Advanced Engineering Technology and Sciences 2023, 8, 391–404, doi:10.30574/wjaets.2023.8.1.0064.
8. Dong, Q.; Bian, Z. Meeting International Economic and Trade Rules: A Case Study of Hainan Free Trade Port, China. World Customs Journal 2024, 18, 78–95, doi:10.55596/001c.116748.

 

Author Response File: Author Response.pdf

Reviewer 3 Report

Comments and Suggestions for Authors

The paper discusses an important topic on to investigate the complex interplay among patient rights, genetic testing, and digital health, as well as the implications for long-term and economic growth, particularly in the area of health and well-being. In addition, it explores how digital technologies may improve healthcare while considering the security precautions and ethical issues that must be taken to promote sustainable development through genetic testing.

The methodology utilized for the research analysis is based on literature review. Though the authors claim literature review, no details on criteria for literature selection was presented. The chaotic nature of literature selection does not allow to comprehend the limitations of the review.

The broad scope of topics covered (patient rights, genetic testing, digital health, and economic growth) in the review narrows down the accuracy and specific details of each domain analysis.

No theoretical framework that would precisely describe the applied methodology and the analysis of the results gives this research little scientific soundness.

In view of the above, major revisions are needed.

Author Response

Reviewer #3:

In response to reviewers’ comments, also find the pdf enclosed with table.

(Manuscript Ref: sustainability-3074310)

The authors gratefully thank the reviewers for their comments and suggestions. We appreciate the reviewer’s comments and advice to improve the quality of our manuscript. We have enclosed the revised manuscript wherein we have addressed all the comments point by point and revised the manuscript accordingly. The major comments are addressed below. All the changes made in the manuscript were highlighted in yellow color

 

Reviewer #3: The paper discusses an important topic on to investigate the complex interplay among patient rights, genetic testing, and digital health, as well as the implications for long-term and economic growth, particularly in the area of health and well-being. In addition, it explores how digital technologies may improve healthcare while considering the security precautions and ethical issues that must be taken to promote sustainable development through genetic testing.

Response: Thank you so much, respected reviewer, for your scholarly comments on a review of our manuscript. We appreciate your observation and are grateful for the opportunity to address your notes, and also examine how digital technologies in, the Hainan Free Trade Zone may improve healthcare while considering the security precautions and ethical issues that must be taken to promote sustainable development through genetic testing, cloud computing, and digital law. We believe this is an important and timely topic, as the rapid advancements in digital health technologies have raised significant questions and concerns around patient privacy, data security, and the ethical use of genetic information. Our manuscript aims to provide a comprehensive analysis of these issues and their potential impact on healthcare and societal well-being. Thank you once again for your constructive review. We try our best to improve the quality of our manuscript based on your suggestions.

 

Reviewer comment# 1. The methodology utilized for the research analysis is based on literature review. Though the authors claim literature review, no details on criteria for literature selection was presented. The chaotic nature of literature selection does not allow to comprehend the limitations of the review.

Response to Reviewer: Thank you, reviewer, for your comment on the methodology used in our paper. We appreciate your concerns regarding the details of the literature review process and the potential limitations of our approach. with many thanks and your full effort in our manuscript, once again thanks and we address all sanctions in the revised manuscript about literature review.

2. Literature review

Cloud computing has become a disruptive force that has a significant effect on the digital economy in today's digital landscape. A wealth of research highlights how cloud computing, defined as having internet-based, on-demand access to computer resources, has completely changed the commercial landscape. Its implications are many and include increased security and compliance, cost-effectiveness, global accessibility, and innovation acceleration through data analytics [1]. The inception of the Web 2.0 landscape has been a subject of extensive academic discussion in recent decades. Scholars have endeavored to comprehend the fundamental changes in how individuals, businesses, and communities interact with the Internet and digital technologies. However, it also points to issues with cybersecurity, data privacy, and fair access. Cloud computing, a key force behind digital transformation, is redefining how companies work together and compete, changing the face of the modern digital economy and highlighting the significance of tackling new issues to ensure its long-term viability and beneficial impact. Big data analytics has become more accessible because of cloud computing, and research in this area shows how businesses may quickly analyze and examine large datasets in real time to get valuable insights about consumer behavior and industry trends. Numerous studies have highlighted how cloud services eliminate the need for pricey on-premises equipment, enabling startups and small businesses to affordably access the same processing capacity as their larger competitors [2].

Although the significance of technologies in the digital economy and sustainable development has been studied in the literature review and legal issues, little research has been done to specifically express, and help how these aspects intersect at the Hainan Free Trade Port, by examining how cutting-edge technologies like cloud computing, Web 2.0, and genetic testing affect the long-term development of the (HFTP), this study seeks to close this gap and digital law. Together with examining the specific policy environment and development objectives of the port, it will also look at the legal and regulatory bases required to secure the proper use of these technologies in the present and future [3].

O'Reilly (2005) is acknowledged for popularizing the term "Web 2.0," emphasizing the shift from a static, publisher-controlled web to a more dynamic, user-centric platform. Subsequent research has delved into the essential features of the Web 2.0 environment, including the emergence of user-generated content, the proliferation of interactive and collaborative web applications, and the growing prominence of platform-based business models.

2.1. The Use of Genetic Testing in the Healthcare

A vital element of the genomic era, genetic testing has grown more and more critical to the digital healthcare sector. It provides a thorough analysis of the complex function of genetic testing and sheds light on its increasing importance in both research and practical application [4]. Finding genetic variants linked to treatment response, illness susceptibility, and preventive measures is the primary goal of genetic testing. Research has demonstrated that it plays a crucial role in the early identification of diseases, providing medical professionals with the ability to customize treatment plans based on a patient's genetic composition and improving patient outcomes.

2.2. Cloud Computing Environments' Privacy Regulations

Global privacy rules are also greatly influenced by the international legal environment (ISO) [5], which is molded by accords like the EU-US Privacy Shield and international data protection standards established by agencies like the International Organization for Standardization [6].

2.3. Both Digital Health and the Economy

The healthcare industry is being significantly impacted by digital health, which is now a crucial part of the developing digital economy. This study sheds light on the transformative forces at work by examining the intricate interactions between digital health and the digital economy. A vast range of advancements are included in the field of digital health, including wearable technology, telemedicine, health informatics, and artificial intelligence [7]. Studies highlight how these blockchain technology developments have transformed the delivery of digital healthcare by permitting real-time data analysis, enabling remote patient monitoring, and encouraging more patient-centered care. Along with improving patient access, the growth of telehealth services, electronic health records, and health applications has also produced new commercial opportunities.

Significant international and national legislation, such as the GDPR of the European Union and the Genetic Information Non-discrimination Act (GINA) of the U.S.A., have established precedents for protecting genetic information from exploitation and discrimination [8,9]. Although these rules offer a starting point, the rapid advancement of blockchain technology has spurred additional conversations on topics such as genetic testing available directly to consumers, genetic information accessibility, and the role of medical professionals.

2.4. Patients' Rights and Privacy Concerns

Legal difficulties in the globalized digital era transcend national borders, requiring international approaches to meet the complex issues brought forward by the constantly changing digital landscape. [10]. It examines the intricate world of international law, highlighting the necessity of law and regulatory harmonization, standardization, and cooperation. Scholars emphasize the increasing importance of global accords and structures, best represented by programs like the European Union's GDPR, which established standards for cybersecurity, privacy, and data protection [11,12]. Global blockchain technology businesses, e-commerce, and cross-border data flows define the digital economy, which highlights the need for international agreement on matters such as cybercrime, data sovereignty, and intellectual property.

Reviewer comment# 2. The broad scope of topics covered (patient rights, genetic testing, digital health, and economic growth) in the review narrows down the accuracy and specific details of each domain analysis.

 

Response to Reviewer: Thank you so much, reviewer, for your scholarly comment on the broad scope of topics covered, we understand your concern about the potential impact on the accuracy and specific details of the analysis for each domain which has been added in the revised version of the manuscript is given below.

China has been actively pushing digital technology development to get closer to global advanced technology development and reform. Furthermore, a positive trend has emerged since 2013, when a series of free trade ports and pilot zones were established, leading the way in high-tech. Hainan Free Trade Port is one of them; it encourages the deep integration of genetic technology research and the innovation chain, with a focus on scientific and technical innovation. The impending complete island closure and the implementation of the Regional Comprehensive Economic Partnership (RCEP) would create favorable circumstances for enhancing Hainan's degree of openness and encouraging the incorporation of genetic technology that meets international standards [13]

The U.S.A. oversees a patchwork of laws, including the could act and state-level privacy protections, to address issues with cross-border data access and privacy. While creating its national cybersecurity strategies and healthcare reforms, the U.K. is taking E.U. directives like GDPR into consideration. Through proposed acts like D.S.A. and D.M.A. and unified standards like GDPR, the E.U. is leading the way in creating harmonized standards for digital services, genetic testing, and data protection. These legislative contexts reflect shifting societal demands and technological surroundings, which in turn show different priorities and methods. The legal systems in those countries handle the complicated problems of genetics, technology, privacy, and healthcare through a range of strategies and focal points. China's legislative policy takes a proactive approach to data protection, as evidenced by its strict cybersecurity policies and regulations, by creating comprehensive rules for cloud computing, with a focus on interoperability, security, and regulatory compliance among service providers. China's stringent regulations on genetic testing, which are detailed in the 2019 Regulation on the Management of Human Genetic Resources, prioritize the privacy of genetic data and strict authorization for collection and distribution [14]. The transformation that the World Wide Web has experienced over the last twenty years has been significant, shifting from a static source of information to a more interactive and user-focused environment known as Web 2.0. This evolution, initiated in the early 2000s, has had a profound impact on how individuals, businesses, and communities interact with online content and services.

China Score has become the market leader worldwide, with an accuracy rate that is 10% higher than FICO, a credit scoring system in the U.S.A., and a considerably higher level than other international systems. Commercial banks have made substantial use of the system since it went online to approve credit cards [15]. Designated regions inside a nation that are created to support economic growth and foreign trade are known as special economic zones. Relaxed rules, tax breaks, and other advantages aimed at luring foreign investment and promoting the growth of export-oriented sectors are typical characteristics of special economic zones [16].

China has inconsistent laws regarding information protection, most of which are legislative status quo stipulations, making it unable to sufficiently protect the personal health information of information subjects. Special laws about cloud computing and information security are, therefore, desperately needed. From the perspective of legislative models, typical examples of decentralized and unified law are the United States and the E.U., respectively. Debates based on Uniform legislation overseeing information collectors' collection, use, and retention of personal data are under E.U. jurisdiction.

This is due to a discussion focused on Medical data in general and genetic data in particular, which are often considered sensitive data that require stringent legal protections. As we've seen in our discussion of permission, data protection and privacy laws are crucial to preserving the confidentiality of personal files containing genetic information. For example, records kept by employers and insurers, as well as medical records, are subject to various federal and provincial legislation.

Table 4. The model presents basic information below

Reviewer comment# 3. No theoretical framework that would precisely describe the applied methodology and the analysis of the results gives this research little scientific soundness. In view of the above, major revisions are needed.

 

Response to Reviewer: Thank you, for your comeback regarding the lack of a theoretical framework and for revisions to improve the scientific soundness of our manuscript, acknowledge your concerns and recognize the importance of grounding our analysis in a well-defined revised manuscript, we have taken the following steps to address this issue the revised version of the manuscript is given below. Once again respected reviewer for your scholarly guidance and manuscript best with your help.

3. Experimental Protocol

The study employs a range of research sources with the primary goal of investigating the interconnected patterns in-laws. It was accomplished by a review of academic papers published in esteemed legal journals, including the International Journal of Law and Information Technology, Yale Law Journal, and Harvard Law Review. Furthermore, documents released by credible organizations such as the World Intellectual Property Organization (WIPO) [17]. The International Data Corporation (I.D.C.), or the European Commission can offer insightful information about the legal aspects of the digital economy and cloud-based genetic testing [18].

Analyzing current legislative contexts governing cybersecurity, data protection, privacy, and intellectual property in the context of the digital economy is part of the inquiry, especially as it relates to genetic data processed and stored on the cloud. Comprehending the needs of regulatory compliance, such as the General Data Protection Regulation (GDPR), is crucial, as is HIPAA [19]. The study investigates the moral ramifications of cloud-based genetic data ownership, access, and use. Evaluating the encryption standards and security measures in place in cloud computing for genetic data is essential to guarantee compliance and reduce the danger of data breaches or illegal access and research methods. Table 1 identifies similarities and valuable insights for the research on the digital economy and genetic testing in the cloud computing environment that can be gained from examining pertinent legal cases or precedents concerning genetic testing, cloud computing, and data privacy.

What legal concerns about data security, privacy, and ethical use of personal information should Web 2.0 environment fosterers, legislators, and regulators about digital health technologies like cloud computing and genetic testing? The paper approach and objective used in this work is formal legal analysis and synthesis. It offers a thorough examination of genetic and legal testing, cloud computing, and the interplay of financial risks in business ventures [20]. Additionally, it focuses on these goals by providing worldwide data exchange and cooperative processing inside an easily adjustable, scalable structure.

 

Special Appreciate to the Reviewer: 3

We all, the authors, are deeply grateful to the reviewers for their time and effort, we express our sincere gratitude to the reviewers for their thoughtful suggestions, which have contributed to the improvement of our manuscript, and many thanks.

 

1. Jeyaraj, R.; Balasubramaniam, A.; M.A., A.K.; Guizani, N.; Paul, A. Resource Management in Cloud and Cloud-Influenced Technologies for Internet of Things Applications. ACM Comput. Surv. 2023, 55, 242:1-242:37, doi:10.1145/3571729.
2. Sharma, S.; Kadayat, Y.; Tyagi, R. Sustainable Global Democratic E-Governance System Using Vedic Scripture, Artificial Intelligence, Cloud Computing and Augmented Reality. In Proceedings of the 2023 International Conference on Circuit Power and Computing Technologies (ICCPCT); August 2023; pp. 113–118.
3. Xiu, C.; Li, T. Construction of the Hainan Free Trade Port from the Perspective of Regional Cultural Development. Front. Earth Sci. 2023, 10, doi:10.3389/feart.2022.1032953.
4. Burke, W.; Burton, H.; Hall, A.E.; Karmali, M.; Khoury, M.J.; Knoppers, B.; Meslin, E.M.; Stanley, F.; Wright, C.F.; Zimmern, R.L. Extending the Reach of Public Health Genomics: What Should Be the Agenda for Public Health in an Era of Genome-Based and “Personalized” Medicine? Genet Med 2010, 12, 785–791, doi:10.1097/GIM.0b013e3182011222.
5. Jamma, S. An Exploration of International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) 17025 Quality Management in the Kansas Department of Agriculture Laboratory, and Food and Drug Administration (FDA) Certification for a Dairy Analysis in a Central Laboratory; 2023;
6. V. L. Aitken, R. Data Privacy Laws &Amp; Social Media Governance : A Comparative Analysis of Tik Tok &Amp; Meta/Facebook Using EU, US, and China’s Data Privacy Laws; 2023;
7. Hou, X.; Zhang, D.; Fu, L.; Zeng, F.; Wang, Q. Spatio-Temporal Evolution and Influencing Factors of Coupling Coordination Degree between Urban–Rural Integration and Digital Economy. Sustainability 2023, 15, 9718, doi:10.3390/su15129718.
8. Branka, M. Big Data and Artificial Intelligence – An Examination of the Existing Legal Framework from a Data Protection Perspective. 2023.
9. Ioan, B.G.; Hanganu, B. Chapter 17 - Third-Party Sharing of Genetic Information. In Clinical Ethics At the Crossroads of Genetic and Reproductive Technologies (Second Edition); Hostiuc, S., Ed.; Academic Press, 2023; pp. 401–429 ISBN 978-0-443-19045-2.
10. Nguyen, M.T.; Tran, M.Q. Balancing Security and Privacy in the Digital Age: An In-Depth Analysis of Legal and Regulatory Frameworks Impacting Cybersecurity Practices. International Journal of Intelligent Automation and Computing 2023, 6, 1–12.
11. Khalil, M.I.; Abdel-Rahman, M. Advanced Cybersecurity Measures in IT Service Operations and Their Crucial Role in Safeguarding Enterprise Data in a Connected World. Eigenpub Review of Science and Technology 2023, 7, 138–158.

 

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

The Authors improved the paper according to the reviewer's comments.

Comments on the Quality of English Language

The english is fine.

Reviewer 3 Report

Comments and Suggestions for Authors

The authors have significantly improved their manuscript, following the reviewer's comments.

1) Literature review. The methodology utilized for the research analysis is based on literature review. The authors  have made literature review selection more comprehensive, which has allowed to avoid the limitations of the review.

2) Scope of topics. In the previous verison, the broad scope of topics covered (patient rights, genetic testing, digital health, and economic growth) in the review narrows down the accuracy and specific details of each domain analysis. To adress the reviewer's concern, some specific details of the analysis for each domain which has been added in the revised version of the manuscript.

3) Theoretical framework.  To improve the scientific soundness of the manuscript, the authors have addressed this issue by adding and describing the concepts that are relevant to the topic of the research paper. Now, the concepts are logically connected. The paper approach and objective used in this work is formal legal analysis and synthesis.

In view of the above, I recommend this paper for publication.