Hochu-Ekki-To Improves Motor Function in an Amyotrophic Lateral Sclerosis Animal Model
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Hochu-Ekki-To (HET) Treatment
2.3. Rota-Rod Test
2.4. Foot Print Test
2.5. Survival Test
2.6. Tissue Preparation
2.7. Western Blotting
2.8. H&E Staining and Immunohistohcemistry
2.9. Statistical Analysis
3. Results
3.1. Hochu-Ekki-(HET) Extended Survival and Improved Motor Function
3.2. Hochu-Ekki-To (HET) Reduces Neuroinflammation and Oxidative Stress in the Spinal Cord of hSOD1G93A Mice
3.3. Hochu-Ekki-To (HET) Attenuates Muscle Dysfunction
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Cai, M.; Yang, E.J. Hochu-Ekki-To Improves Motor Function in an Amyotrophic Lateral Sclerosis Animal Model. Nutrients 2019, 11, 2644. https://doi.org/10.3390/nu11112644
Cai M, Yang EJ. Hochu-Ekki-To Improves Motor Function in an Amyotrophic Lateral Sclerosis Animal Model. Nutrients. 2019; 11(11):2644. https://doi.org/10.3390/nu11112644
Chicago/Turabian StyleCai, Mudan, and Eun Jin Yang. 2019. "Hochu-Ekki-To Improves Motor Function in an Amyotrophic Lateral Sclerosis Animal Model" Nutrients 11, no. 11: 2644. https://doi.org/10.3390/nu11112644