Impact of Nutrition on Enhanced Recovery After Surgery (ERAS) in Gynecologic Oncology
Round 1
Reviewer 1 Report
In this review, the authors discuss the importance of nutritional assessment and intervention during the pre-operative and post-operative period in the context of ERAS (Enhanced Recovery After Surgery) in gynecologic oncology surgery.
This is a well-organized review, but I have some comments.
The authors should provide an explanation for ‘immunonutrition.’ Why are these nutrients (polyunsaturated/omega-3 fatty acids, arginine, glutamine, antioxidants, and nucleotides) immune-enhancing?
In the ‘Preoperative nutritional status’ section, five nutritional screening scores are listed. References for these scores are necessary.
Line 56. The discontinuation of excessive alcohol intake. 4-6 weeks (or days?) preoperatively?
Line 83. Although I can imagine what ‘gastrostasis’ is, the authors should give the definition of ‘gastrostasis.’
Line 84. Why should care be paid to the situation with increased estrogen/progesterone levels? In gynecologic oncology, what diseases are associated with this situation? Please explain.
Line 107. Maltodextrin is a purified concentrated aqueous solution or the dried product from the solution. In order to avoid confusion, please clarify.
References. Volumes and pages are missing in many citations.
Author Response
The authors should provide an explanation for ‘immunonutrition.’ Why are these nutrients (polyunsaturated/omega-3 fatty acids, arginine, glutamine, antioxidants, and nucleotides) immune-enhancing?
Completed
In the ‘Preoperative nutritional status’ section, five nutritional screening scores are listed. References for these scores are necessary.
Completed
Line 56. The discontinuation of excessive alcohol intake. 4-6 weeks (or days?) preoperatively?
Completed
Line 83. Although I can imagine what ‘gastrostasis’ is, the authors should give the definition of ‘gastrostasis.’
Completed
Line 84. Why should care be paid to the situation with increased estrogen/progesterone levels? In gynecologic oncology, what diseases are associated with this situation? Please explain.
Completed
Line 107. Maltodextrin is a purified concentrated aqueous solution or the dried product from the solution. In order to avoid confusion, please clarify.
Completed
References. Volumes and pages are missing in many citations.
Completed
Reviewer 2 Report
well written review
Making a summary table may be helpful to guide the nutritional support or ERAS for gynecologist or gynecologic oncologist.
Author Response
Making a summary table may be helpful to guide the nutritional support or ERAS for gynecologist or gynecologic oncologist.
Completed (see attached new Table 1)
