Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome
Abstract
:1. Introduction
2. The Endocannabinoidome
3. Dietary Fats and the Endocannabinoidome
4. Dietary Fiber and Prebiotics: Improving Gut Barrier Function through the Endocannabinoidome
5. TRPV1: Linking the Endocannabinoidome to the Metabolic Benefits Attributed to Spicy Food
6. Sunlight Effects on the Endocannabinoidome: A Role for Vitamin D?
7. Effects of Exercise on the Endocannabinoidome
8. Cannabis Use and Metabolic Health
9. Conclusions
Author Contributions
Funding
Conflicts of Interest
Abbreviations
Mediators | |
2-AcGs | 2-acylglycerols |
2-AG | 2-arachidonoylglycerol |
2-LG | 2-linoleoyl glycerol |
2-OG | 2-oleoylglycerol |
AcNeuro | acyl neurotransmitters |
AEA | N-arachidonoylethanolamine |
DHEA | N-docosahexanoylethanolamine |
LEA | N-linoleoylethanolamine |
Lipo-AAs | lipoamino acids |
NAEs | N-acylethanolamines |
OA | oleoylamide |
OEA | N-oleoylethanolamine |
PA | fatty acid primary amides |
PEA | N-palmitoylethanolamine |
Receptors | |
Cav3 | T-type Ca2+ channel |
CB1 | cannabinoid receptor 1 |
CB2 | cannabinoid receptor 2 |
GPR110 | G protein-coupled receptor 110 |
GPR119 | G protein-coupled receptor 119 |
GPR18 | G protein-coupled receptor 18 |
GPR55 | G protein-coupled receptor 55 |
PPARA | peroxisome proliferator-activated receptor alpha |
PPARG | peroxisome proliferator-activated receptor gamma |
TRPV1 | transient receptor potential cation channel sub-family V member 1 |
TRPV4 | transient receptor potential cation channel subfamily V member 4 |
Anabolic enzymes | |
AANATL2 | arylalkylamine N-acyltransferase-like 2, isoform A |
ABHD4 | alpha/beta-hydrolase domain containing 4 |
DAGLA/B | diacylglycerol lipase alpha/beta |
GDE1 | glycerophosphodiester phosphodiesterase 1 |
GLYATL3 | glycine N-acyltransferase-like protein 3 |
LPA-Phos | lysophosphatidic acid phosphatase |
Lyso-PLC | lysophospholipase C Lyso-PLC, lysophospholipase D |
NAPEPLD | N-acyl phosphatidylethanolamine-hydrolyzing phospholipase D |
PA-phos. hyd. | phosphatidic acid phosphohydrolase |
PLA1A | phospholipase A1 member A |
PLC | phospholipase C |
PLCB | phospholipase C beta |
PTPN22 | tyrosine protein phosphatase non-receptor type 22 |
sPLA2 | soluble phospholipase A2. |
Catabolic enzymes | |
ABHD12 | alpha/beta-hydrolase domain containing 12 |
ABHD6 | alpha/beta hydrolase domain containing 6 |
COMT | catechol-O-methyltransferase |
COX2 | cyclooxygenase 2 |
CYP450 | cytochrome P450 |
FAAH | fatty acid amide hydrolase |
LOX12/15 | arachidonate lipoxygenase 12/15 |
MAGK | monoacylglycerol kinase |
MGLL | monoacylglycerol lipase |
NAAA | N-acylethanolamine-hydrolyzing acid amidase |
PAM | peptidyl-glycine α-amidating monooxygenase |
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Di Marzo, V.; Silvestri, C. Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome. Nutrients 2019, 11, 1956. https://doi.org/10.3390/nu11081956
Di Marzo V, Silvestri C. Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome. Nutrients. 2019; 11(8):1956. https://doi.org/10.3390/nu11081956
Chicago/Turabian StyleDi Marzo, Vincenzo, and Cristoforo Silvestri. 2019. "Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome" Nutrients 11, no. 8: 1956. https://doi.org/10.3390/nu11081956