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Nutrients
Volume 13
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10.3390/nu13114018
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Review

Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update

by
Marianna Pellegrini
1,
Chiara D'Eusebio
1,
Valentina Ponzo
1,
Luca Tonella
2,
Concetta Finocchiaro
3,
Maria Teresa Fierro
2,
Pietro Quaglino
2,*,† and
Simona Bo
1,†
1
Department of Medical Sciences, Division of Endocrinology, Diabetes and Metabolism, University of Torino, 10126 Torino, Italy
2
Department of Medical Sciences, Dermatologic Clinic, University of Torino, 10126 Torino, Italy
3
Dietetic and Clinical Nutrition Unit, “Città della Salute e della Scienza” Hospital, 10126 Torino, Italy
*
Author to whom correspondence should be addressed.
†
Both authors contributed equally to this work.
Nutrients 2021, 13(11), 4018; https://doi.org/10.3390/nu13114018
Submission received: 9 September 2021 / Revised: 31 October 2021 / Accepted: 8 November 2021 / Published: 11 November 2021
(This article belongs to the Section Nutritional Epidemiology)
Review Reports Versions Notes

Abstract

Melanoma is an aggressive skin cancer, whose incidence rates have increased over the past few decades. Risk factors for melanoma are both intrinsic (genetic and familiar predisposition) and extrinsic (environment, including sun exposure, and lifestyle). The recent advent of targeted and immune-based therapies has revolutionized the treatment of melanoma, and research is focusing on strategies to optimize them. Obesity is an established risk factor for several cancer types, but its possible role in the etiology of melanoma is controversial. Body mass index, body surface area, and height have been related to the risk for cutaneous melanoma, although an ‘obesity paradox’ has been described too. Increasing evidence suggests the role of nutritional factors in the prevention and management of melanoma. Several studies have demonstrated the impact of dietary attitudes, specific foods, and nutrients both on the risk for melanoma and on the progression of the disease, via the effects on the oncological treatments. The aim of this narrative review was to summarize the main literature results regarding the preventive and therapeutic role of nutritional schemes, specific foods, and nutrients on melanoma incidence and progression.
Keywords: melanoma; diet; nutrition; obesity melanoma; diet; nutrition; obesity

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MDPI and ACS Style

Pellegrini, M.; D'Eusebio, C.; Ponzo, V.; Tonella, L.; Finocchiaro, C.; Fierro, M.T.; Quaglino, P.; Bo, S. Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update. Nutrients 2021, 13, 4018. https://doi.org/10.3390/nu13114018

AMA Style

Pellegrini M, D'Eusebio C, Ponzo V, Tonella L, Finocchiaro C, Fierro MT, Quaglino P, Bo S. Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update. Nutrients. 2021; 13(11):4018. https://doi.org/10.3390/nu13114018

Chicago/Turabian Style

Pellegrini, Marianna, Chiara D'Eusebio, Valentina Ponzo, Luca Tonella, Concetta Finocchiaro, Maria Teresa Fierro, Pietro Quaglino, and Simona Bo. 2021. "Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update" Nutrients 13, no. 11: 4018. https://doi.org/10.3390/nu13114018

APA Style

Pellegrini, M., D'Eusebio, C., Ponzo, V., Tonella, L., Finocchiaro, C., Fierro, M. T., Quaglino, P., & Bo, S. (2021). Nutritional Interventions for Patients with Melanoma: From Prevention to Therapy—An Update. Nutrients, 13(11), 4018. https://doi.org/10.3390/nu13114018

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