Next Article in Journal
Microbial Diversity and Characteristics of Kombucha as Revealed by Metagenomic and Physicochemical Analysis
Next Article in Special Issue
Protective Effects of Spirulina maxima against Blue Light-Induced Retinal Damages in A2E-Laden ARPE-19 Cells and Balb/c Mice
Previous Article in Journal
Raphani Semen (Raphanus sativus L.) Ameliorates Alcoholic Fatty Liver Disease by Regulating De Novo Lipogenesis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 13
Issue 12
10.3390/nu13124449
Review Report
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

A Pilot, Phase II, Observational, Case-Control, 1-Month Study on Asthenopia in Video Terminal Operators without Dry Eye: Contrast Sensitivity and Quality of Life before and after the Oral Consumption of a Fixed Combination of Zinc, L-Carnitine, Extract of Elderberry, Currant and Extract of Eleutherococcus.

Nutrients 2021, 13(12), 4449; https://doi.org/10.3390/nu13124449
by Gemma Caterina Maria Rossi 1,*, Luigia Scudeller 2, Federica Bettio 1 and Giovanni Milano 1
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Nutrients 2021, 13(12), 4449; https://doi.org/10.3390/nu13124449
Submission received: 8 November 2021 / Revised: 7 December 2021 / Accepted: 9 December 2021 / Published: 13 December 2021
(This article belongs to the Special Issue Lifestyle, Diet and Nutraceuticals in the Management of Age-Related Diseases of the Eye: Where Are We Now?)

Round 1

Reviewer 1 Report

  1. Thorough proof-reading for spelling grammar and sentence structure is needed. For example:
  • Page 1, line 36 should be changed to “The prolonged use of video terminals not only generate muscolo-skeletal disorders, but also cause ocular complications
  • Line 38, change “pandemy” to pandemic
  • Line 164, correct “Fifhteen” to “Fifteen”
  1. Page 3 line 135to 150 should be moved to an appropriate point in the discussion instead of the materials and methods section.
  2. In the results section, a table for subject demographics would suit better
  3. Was the observer masked? If not, then once again the study results are highly subject to bias.
  4. Discussion line 196 “Is it possible to improve the quality of vision and also the quality of life of video terminal workers with the intake of some nutraceuticals with specific effects on sight? Our data should answer yes” This line sounds like advertorial rather than an authentic research article.
  5. Considering that this was open label study with no placebos, randomization or masking, self-reported symptoms questionnaires are subject to a high degree of bias. Moreover, the sample size is very small and only a minimal statistical significance was observed for visual acuity by an unmasked observer. Therefore, the authors should tread with caution in interpreting the data and refrain from making any sweeping statements.

 

Author Response

please see the attachment

Author Response File: Author Response.doc

Reviewer 2 Report

I read the manuscript with interest as the design of experiment was very close to real life. It would be nice to review the manuscript carefully and correct typo. In addition, if there was a positive treatment group with lutein or zeaxanthin. 

Author Response

please see the attachment

Author Response File: Author Response.doc

Round 2

Reviewer 1 Report

Professional proof-reading and editing for English Language style is recommended

 

Author Response

Dear Reviewer

the manuscript has been revised for style and English editing

Back to TopTop