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Article
Peer-Review Record

Vitamin D and Hospital Admission in Older Adults: A Prospective Association

Nutrients 2021, 13(2), 616; https://doi.org/10.3390/nu13020616
by Avril Beirne 1,*, Kevin McCarroll 2, James Bernard Walsh 2, Miriam Casey 2, Eamon Laird 3, Helene McNulty 4, Mary Ward 4, Leane Hoey 4, Anne M. Molloy 3, Martin Healy 5, Catherine Hughes 4, Sean Strain 4 and Conal Cunningham 2
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Nutrients 2021, 13(2), 616; https://doi.org/10.3390/nu13020616
Submission received: 28 January 2021 / Revised: 8 February 2021 / Accepted: 8 February 2021 / Published: 14 February 2021
(This article belongs to the Section Nutritional Epidemiology)

Round 1

Reviewer 1 Report

According to Table 1, >60% of the patients had taken Vit D - supplements:

Please indicate in addition  the Vit D dose range.

Line 258 pp: Please discuss the dosing of Vit D-supplements: enough - or in (de)crease dosings?

How long did patients take the supplements - did they really take them??

Should dosing generally  be in(de)creased: yes or no? Precautions?

Author Response

Many thanks for your comments and suggestions.

The supplementation of Vitamin D was not instituted as part of this study. Participants self-reported their vitamin D supplements with doses ranging from 100IU to 800IU per day.

Compliance was not recorded as we did not initiate supplementation therefore I can not accurately comment on this or the duration of therapy prior to recruitment, unfortunately.

So this leaves it difficult to say if their doses should be adjusted. I can recommend that those deficient need depletion and avoidance of supra- supplementation?

Many thanks,

Avril

Reviewer 2 Report

The manuscript determines the relationship of vitamin D status in older adults with hospital admission and emergency department attendance.

Authors found inverse associations of vitamin D with hospital admission. According to the author, vitamin D supplementation will improve the disease states of cognition, bone health, and hypertension.

The author presents a nice piece of work that will recommend vitamin D supplementation in older adults. In my opinion, this work is acceptable.

  • The title and abstract reflect the content of the work.
  • The introduction section requires some improvement. Please add the role of vitamin D in cognition, bone health, and hypertension.
  • The authors have performed good statistical analysis to find an association between vitamin D and cognition, bone health, and hypertension in older adults.
  • Discussion and explanations of the obtained results were made correctly.
  • The selected topic is interesting. The work is properly documented.

Author Response

Many thanks for your review. I have made the suggested improvement to the introduction in the manuscript.

Thanks, Avril Beirne 

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