Next Article in Journal
The Utility of Oral Vitamin B1 and Mecobalamin to Improve Corneal Nerves in Dry Eye Disease: An In Vivo Confocal Microscopy Study
Next Article in Special Issue
Colorectal Cancer and the Role of the Gut Microbiota—Do Medical Students Know More Than Other Young People?—Cross-Sectional Study
Previous Article in Journal
Dietary Acid Load Was Positively Associated with the Risk of Hip Fracture in Elderly Adults
Previous Article in Special Issue
Overgrowth of Squamocolumnar Junction and Dysregulation of Stem Cell Lineages in the Stomach of Vitamin A-Deficient Mice
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nutrients
Volume 14
Issue 18
10.3390/nu14183749
nutrients-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention

by
Raffaella Memmola
1,
Angelica Petrillo
2,
Sara Di Lorenzo
2,3,
Sara C. Altuna
4,
Baker Shalal Habeeb
5,
Alessio Soggiu
1,
Luigi Bonizzi
1,
Ornella Garrone
6,† and
Michele Ghidini
6,*,†
1
Department of Biochemical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy
2
Medical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy
3
School of Medicine, University of Study of Campania “L. Vanvitelli”, 80131 Naples, Italy
4
Medical Oncology, Oncomedica C.A., Caracas 1060, Venezuela
5
Oncology Department, Shaqlawa Teaching Hospital, Shaqlawa City 44005, Iraq
6
Oncology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20131 Milan, Italy
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Nutrients 2022, 14(18), 3749; https://doi.org/10.3390/nu14183749
Submission received: 10 August 2022 / Revised: 3 September 2022 / Accepted: 6 September 2022 / Published: 10 September 2022
(This article belongs to the Special Issue Diet, Microbioma and Gastrointestinal Cancers)
Browse Figures
Versions Notes

Abstract

Extra virgin olive oil (EVOO) is a mainstay of the Mediterranean diet with its excellent balance of fats and antioxidant bioactive compounds. Both the phenolic and lipid fractions of EVOO contain a variety of antioxidant and anticancer substances which might protect from the development of colorectal cancer (CRC). The function of the intestinal microbiome is essential for the integrity of the intestinal epithelium, being protective against pathogens and maintaining immunity. Indeed, dysbiosis of the microbiota alters the physiological functions of the organ, leading to the onset of different diseases including CRC. It is known that some factors, including diet, could deeply influence and modulate the colon microenvironment. Although coming from animal models, there is increasing evidence that a diet rich in EVOO is linked to a significant reduction in the diversity of gut microbiome (GM), causing a switch from predominant bacteria to a more protective group of bacteria. The potential beneficial effect of the EVOO compounds in the carcinogenesis of CRC is only partially known and further trials are needed in order to clarify this issue. With this narrative review, we aim at discussing the available evidence on the effect of olive oil consumption on GM in the prevention of CRC.
Keywords: extra virgin olive oil; microbiota; colorectal cancer; olive oil; antioxidants; EVOO extra virgin olive oil; microbiota; colorectal cancer; olive oil; antioxidants; EVOO
Graphical Abstract

Share and Cite

MDPI and ACS Style

Memmola, R.; Petrillo, A.; Di Lorenzo, S.; Altuna, S.C.; Habeeb, B.S.; Soggiu, A.; Bonizzi, L.; Garrone, O.; Ghidini, M. Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention. Nutrients 2022, 14, 3749. https://doi.org/10.3390/nu14183749

AMA Style

Memmola R, Petrillo A, Di Lorenzo S, Altuna SC, Habeeb BS, Soggiu A, Bonizzi L, Garrone O, Ghidini M. Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention. Nutrients. 2022; 14(18):3749. https://doi.org/10.3390/nu14183749

Chicago/Turabian Style

Memmola, Raffaella, Angelica Petrillo, Sara Di Lorenzo, Sara C. Altuna, Baker Shalal Habeeb, Alessio Soggiu, Luigi Bonizzi, Ornella Garrone, and Michele Ghidini. 2022. "Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention" Nutrients 14, no. 18: 3749. https://doi.org/10.3390/nu14183749

APA Style

Memmola, R., Petrillo, A., Di Lorenzo, S., Altuna, S. C., Habeeb, B. S., Soggiu, A., Bonizzi, L., Garrone, O., & Ghidini, M. (2022). Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention. Nutrients, 14(18), 3749. https://doi.org/10.3390/nu14183749

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop