Microbiome and Asthma: Microbial Dysbiosis and the Origins, Phenotypes, Persistence, and Severity of Asthma
Round 1
Reviewer 1 Report
This review represents a comprehensive overview of different factors and pathophsiological explanations of the asthma as well as the potential solutions and treatment options.
With the insight into next-gen sequencing, microbiology of the gut and airways, it is giving the readers many information and previously published results in one paper.
Author Response
Thank you very much for your very positive comments.
Reviewer 2 Report
This manuscript is a very interesting review of dysbiosis and asthma aetiology and severity regarding the microbiome modulation of the gut-lung axis during the first days of life and lifecycle. Moreover, the authors highlight that dietary patterns and diet diversity could also be a window of opportunity to change the composition of the gut and airways microbiome to prevent asthma and reduce asthma persistency and severity; and reinforces that Nutritionists and Nutrition Experts should be more broadly incorporated in the multidisciplinary units to prevent and manage asthma.
Author Response
Thank you so much for your very positive observations.
