Electrochemical Detection of Alpha-Fetoprotein Based on Black Phosphorus Nanosheets Modification with Iron Ions
Abstract
:1. Introduction
2. Experimental
2.1. Reagents and Instruments
2.2. Synthesis of BPNSs
2.3. Synthesis of Fe3+/BPNSs
2.4. MTT Assay
2.5. Electrochemical Characterization
2.6. Detection of Alpha-Fetoprotein
3. Results and Discussion
3.1. Characterization of BPNSs and Fe3+/BPNSs
3.1.1. Structural Analysis
3.1.2. Spectroscopy Analysis
3.1.3. Electrochemical Analysis of Fe3+/BPNSs
3.1.4. Cytotoxicity of Fe3+/BPNSs
3.2. Optimization of Experimental Conditions
3.3. Electrochemical Determination of Alpha-Fetoprotein
3.4. Selectivity of the Electrochemical Immunosensors
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Chen, Y.; Chen, X.; Lin, J.; Zhuang, Y.; Han, Z.; Chen, J. Electrochemical Detection of Alpha-Fetoprotein Based on Black Phosphorus Nanosheets Modification with Iron Ions. Micromachines 2022, 13, 673. https://doi.org/10.3390/mi13050673
Chen Y, Chen X, Lin J, Zhuang Y, Han Z, Chen J. Electrochemical Detection of Alpha-Fetoprotein Based on Black Phosphorus Nanosheets Modification with Iron Ions. Micromachines. 2022; 13(5):673. https://doi.org/10.3390/mi13050673
Chicago/Turabian StyleChen, Yiyan, Xiaoping Chen, Jianwei Lin, Yafeng Zhuang, Zhizhong Han, and Jinghua Chen. 2022. "Electrochemical Detection of Alpha-Fetoprotein Based on Black Phosphorus Nanosheets Modification with Iron Ions" Micromachines 13, no. 5: 673. https://doi.org/10.3390/mi13050673