High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip
Abstract
:1. Introduction
2. Results
2.1. Establishment of Heart-on-a-Chip
2.2. Heart-on-a-Chip for Antiarrhythmic Drug Test
2.3. Heart-on-a-Chip for Anticancer Drug Test
2.4. Cell Viability Test by Impedance Detection Method
3. Materials and Methods
3.1. Device Fabrication
3.2. Cell Culture
3.3. Impedance Measurement
3.4. Drug Treatment
3.5. Statistical Analysis
4. Discussion and Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Zhang, X.; Wang, T.; Wang, P.; Hu, N. High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip. Micromachines 2016, 7, 122. https://doi.org/10.3390/mi7070122
Zhang X, Wang T, Wang P, Hu N. High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip. Micromachines. 2016; 7(7):122. https://doi.org/10.3390/mi7070122
Chicago/Turabian StyleZhang, Xi, Tianxing Wang, Ping Wang, and Ning Hu. 2016. "High-Throughput Assessment of Drug Cardiac Safety Using a High-Speed Impedance Detection Technology-Based Heart-on-a-Chip" Micromachines 7, no. 7: 122. https://doi.org/10.3390/mi7070122