Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers
Abstract
:1. Introduction
2. Time-Resolved Crystallography at Synchrotron Sources
3. Free-Electron Lasers
3.1. Injector Systems
3.2. Detectors
4. Time-Resolved Serial Femtosecond Crystallography (TR-SFX)
5. Designing Pump-Probe TR-SFX Experiments.
6. Data Processing: From Diffraction Patterns to Structure Determination in TRX
6.1. Indexing and Three-Dimensional Merging of Diffraction Patterns
6.2. Difference Maps and Structure Determination
7. TR-SFX on Photoactive Yellow Protein
8. Biological Relevance of Pump-Probe TR-SFX
9. Outlook
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Pandey, S.; Poudyal, I.; Malla, T.N. Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers. Crystals 2020, 10, 628. https://doi.org/10.3390/cryst10070628
Pandey S, Poudyal I, Malla TN. Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers. Crystals. 2020; 10(7):628. https://doi.org/10.3390/cryst10070628
Chicago/Turabian StylePandey, Suraj, Ishwor Poudyal, and Tek Narsingh Malla. 2020. "Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers" Crystals 10, no. 7: 628. https://doi.org/10.3390/cryst10070628