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Article
Peer-Review Record

3D Bio-Printing of CS/Gel/HA/Gr Hybrid Osteochondral Scaffolds

Polymers 2019, 11(10), 1601; https://doi.org/10.3390/polym11101601
by Xueyan Hu 1, Yuan Man 1, Wenfang Li 1, Liying Li 1, Jie Xu 1, Roxanne Parungao 2, Yiwei Wang 2, Shuangshuang Zheng 3, Yi Nie 3,4,*, Tianqing Liu 1,* and Kedong Song 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Polymers 2019, 11(10), 1601; https://doi.org/10.3390/polym11101601
Submission received: 26 August 2019 / Revised: 19 September 2019 / Accepted: 27 September 2019 / Published: 30 September 2019
(This article belongs to the Special Issue 3D and 4D Printing of (Bio)Materials)

Round 1

Reviewer 1 Report

Line 92 - The authors should better explain which solvent they used to make the Cs/Gels/HA/GR  solution.

Line 93 - The authors mixed CS, gelatin, hyaluronic acid. Gelatin is a pH sensitive polymer, the authors must indicate which was the working pH.

Line 93 - Graphene is not soluble in water, the author should explain how they prepare a GR solution.

Line 94 - It is not clear if the scaffold s are made of Cs/Gels/HA/GR or each single polymer made a scaffold. Please explain.

Line 96 - If BMSCs were seeded onto the scaffold, which was the advantage of 3D-bioprinting? Usually  cells are mixed with the bioink and printed.

Line 109 - Gelatinn and  hyalyuronic acid should be added in the Materials section.

Line 121 - carbodiimide / N-hydroxy-succinamide / morpholine ethane sulfonate  should be reported in the Materials section.

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Dear Authors

This manuscript is quite good for the future researchers to work, could you please follow my suggestions for the betterment of the paper;

 

1) Improve your Scientific English

2) Improve the Introduction and Conclusion linked it with an experiment. 

Other is fine 

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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