3D Bio-Printing of CS/Gel/HA/Gr Hybrid Osteochondral Scaffolds
Round 1
Reviewer 1 Report
Line 92 - The authors should better explain which solvent they used to make the Cs/Gels/HA/GR solution.
Line 93 - The authors mixed CS, gelatin, hyaluronic acid. Gelatin is a pH sensitive polymer, the authors must indicate which was the working pH.
Line 93 - Graphene is not soluble in water, the author should explain how they prepare a GR solution.
Line 94 - It is not clear if the scaffold s are made of Cs/Gels/HA/GR or each single polymer made a scaffold. Please explain.
Line 96 - If BMSCs were seeded onto the scaffold, which was the advantage of 3D-bioprinting? Usually cells are mixed with the bioink and printed.
Line 109 - Gelatinn and hyalyuronic acid should be added in the Materials section.
Line 121 - carbodiimide / N-hydroxy-succinamide / morpholine ethane sulfonate should be reported in the Materials section.
Author Response
Please see the attachment.
Author Response File: Author Response.docx
Reviewer 2 Report
Dear Authors
This manuscript is quite good for the future researchers to work, could you please follow my suggestions for the betterment of the paper;
1) Improve your Scientific English
2) Improve the Introduction and Conclusion linked it with an experiment.
Other is fine
Author Response
Please see the attachment.
Author Response File: Author Response.docx