A Strategy of In Situ Catalysis and Nucleation of Biocompatible Zinc Salts of Amino Acids towards Poly(l-lactide) with Enhanced Crystallization Rate
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Synthesis of Zinc Amino Acids (Zn(AA)2)
2.3. Preparation of PLLA Catalyzed by Zinc Amino Acids (Zn(AA)2)
2.4. Characterization
3. Results and Discussion
3.1. Synthesis and Characterization
3.2. Isothermal Crystallization Kinetics
3.3. Thermal Stability
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Catalysts | Mn,theory (kg/mol) | Yield (%) | Mn,SECb (kg/mol) | Mw,SECb (kg/mol) | Ð b | [α] (°) c | [O.P.] (%) d |
---|---|---|---|---|---|---|---|
Sn(Oct)2 | 14.4 | 99 | 14.2 | 19.6 | 1.37 | −156 | 100 |
Zn(l-Ala)2 | 14.4 | 98 | 6.8 | 9.3 | 1.30 | −142.8 | 91.5 |
Zn(d-Ala)2 | 14.4 | 97 | 15.5 | 21.8 | 1.40 | −148.3 | 95.0 |
Zn(dl-Ala)2 | 14.4 | 99 | 10.5 | 13.5 | 1.27 | −144.6 | 94.5 |
Zn(d-Phe)2 | 14.4 | 98 | 14.3 | 17.1 | 1.19 | −149.9 | 96.0 |
Zn(l-Phe)2 | 14.4 | 99 | 13.1 | 16.5 | 1.25 | −144.6 | 92.6 |
Zn(dl-Phe)2 | 14.4 | 99 | 12.6 | 16.7 | 1.32 | −149.9 | 96.0 |
Zn(l-Pro)2 | 14.4 | 99 | 12.6 | 16.9 | 1.33 | −151.7 | 97.2 |
Zn(d-Pro)2 | 14.4 | 97 | 8.8 | 11.8 | 1.33 | −148.3 | 95.0 |
Zn(dl-Pro)2 | 14.4 | 99 | 14.3 | 20.1 | 1.40 | −148.4 | 95.1 |
Catalysts | n | k (min−n) | t1/2 (min) |
---|---|---|---|
Sn(Oct)2 | 2.25 | 7.0 × 10−3 | 7.87 |
Zn(l-Ala)2 | 2.35 | 1.8 × 10−2 | 4.60 |
Zn(d-Ala)2 | 2.81 | 3.5 × 10−2 | 2.85 |
Zn(dl-Ala)2 | 2.92 | 2.3 × 10−2 | 3.15 |
Zn(d-Phe)2 | 2.65 | 5.2 × 10−2 | 2.54 |
Zn(l-Phe)2 | 3.68 | 1.8 × 10−2 | 3.26 |
Zn(dl-Phe)2 | 2.87 | 3.8 × 10−2 | 3.31 |
Zn(l-Pro)2 | 2.88 | 0.87 | 0.89 |
Zn(d-Pro)2 | 2.37 | 6.1 × 10−2 | 2.70 |
Zn(dl-Pro)2 | 2.80 | 0.13 | 1.88 |
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Liang, Y.; Sui, M.; He, M.; Wei, Z.; Zhang, W. A Strategy of In Situ Catalysis and Nucleation of Biocompatible Zinc Salts of Amino Acids towards Poly(l-lactide) with Enhanced Crystallization Rate. Polymers 2019, 11, 790. https://doi.org/10.3390/polym11050790
Liang Y, Sui M, He M, Wei Z, Zhang W. A Strategy of In Situ Catalysis and Nucleation of Biocompatible Zinc Salts of Amino Acids towards Poly(l-lactide) with Enhanced Crystallization Rate. Polymers. 2019; 11(5):790. https://doi.org/10.3390/polym11050790
Chicago/Turabian StyleLiang, Yuan, Meili Sui, Maomao He, Zhiyong Wei, and Wanxi Zhang. 2019. "A Strategy of In Situ Catalysis and Nucleation of Biocompatible Zinc Salts of Amino Acids towards Poly(l-lactide) with Enhanced Crystallization Rate" Polymers 11, no. 5: 790. https://doi.org/10.3390/polym11050790