A Collagen-Based Scaffold for Promoting Neural Plasticity in a Rat Model of Spinal Cord Injury
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of Collagen Scaffold
2.2. Physical Characteristics of the Collagen Scaffold
2.2.1. Fourier Transform Infra-red (FTIR) Spectroscopy
2.2.2. Scanning Electron Microscopy (SEM)
2.3. In Vitro Biocompatibility
2.4. Rat Spinal Cord Injury Model
2.5. Immunofluorescence Analysis
3. Results and Discussion
3.1. Morphology and In Vitro Biocompatibility of the Collagen Scaffold
3.2. In Vivo Biocompatibility and Immunofluorescence of the Implanted Collagen Scaffold in the Rat Spinal Cord Injury Model
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Yeh, J.-Z.; Wang, D.-H.; Cherng, J.-H.; Wang, Y.-W.; Fan, G.-Y.; Liou, N.-H.; Liu, J.-C.; Chou, C.-H. A Collagen-Based Scaffold for Promoting Neural Plasticity in a Rat Model of Spinal Cord Injury. Polymers 2020, 12, 2245. https://doi.org/10.3390/polym12102245
Yeh J-Z, Wang D-H, Cherng J-H, Wang Y-W, Fan G-Y, Liou N-H, Liu J-C, Chou C-H. A Collagen-Based Scaffold for Promoting Neural Plasticity in a Rat Model of Spinal Cord Injury. Polymers. 2020; 12(10):2245. https://doi.org/10.3390/polym12102245
Chicago/Turabian StyleYeh, Jue-Zong, Ding-Han Wang, Juin-Hong Cherng, Yi-Wen Wang, Gang-Yi Fan, Nien-Hsien Liou, Jiang-Chuan Liu, and Chung-Hsing Chou. 2020. "A Collagen-Based Scaffold for Promoting Neural Plasticity in a Rat Model of Spinal Cord Injury" Polymers 12, no. 10: 2245. https://doi.org/10.3390/polym12102245