Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization
Abstract
:1. Introduction
2. Materials and Methods
2.1. Raman Spectroscopy
2.2. Sample Preparation
2.3. Experimental Procedure
3. Results
3.1. Raman Spectroscopic Characterization of Polymerization Process
3.1.1. Characterization of Fast Polymerization Phase
3.1.2. Characterization of Slow Polymerization Phase
3.2. Effect of GO Proportion on the Polymerization Process
3.3. Effect of Blood Composition on the Polymerization Process
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Glue Concentration | Blood | Fast Phase | Slow Phase |
---|---|---|---|
Substitute | (z = 1 mm) | (z = 5 mm) | |
67% | BSA8 | — | 8616.8 ± 1145.2 s |
50% | BSA8 | 21.8 ± 4.3 s | 3073.6 ± 531.9 s |
33% | BSA8 | 96.3 ± 10.2 s | 7514.9 ± 883.6 s |
Glue Concentration | Blood | Fast Phase | Slow Phase |
---|---|---|---|
Substitute | (z = 1 mm) | (z = 5 mm) | |
50% | BSA4 | 23.6 ± 4.8 s | 6720.1 ± 1088.7 s |
50% | BSA8 | 21.8 ± 4.3 s | 3073.6 ± 531.9 s |
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Li, Y.; Xiao, L.; Wang, Z.; Chen, K.; Xue, C.; Yu, M.; Wang, Y.; Kong, F.; Liu, K.; Qin, K. Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization. Polymers 2021, 13, 3362. https://doi.org/10.3390/polym13193362
Li Y, Xiao L, Wang Z, Chen K, Xue C, Yu M, Wang Y, Kong F, Liu K, Qin K. Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization. Polymers. 2021; 13(19):3362. https://doi.org/10.3390/polym13193362
Chicago/Turabian StyleLi, Yongjiang, Lei Xiao, Zian Wang, Kejie Chen, Chundong Xue, Miao Yu, Yu Wang, Fanyi Kong, Kun Liu, and Kairong Qin. 2021. "Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization" Polymers 13, no. 19: 3362. https://doi.org/10.3390/polym13193362