Molecular Imprinting Technology for Advanced Delivery of Essential Oils
Abstract
:1. Introduction
2. Essential Oils’ Active Substances as Part of MIP
3. Opportunities to Apply Molecular Imprinting Technologies for the Delivery of Essential Oils
3.1. The Most Promising Types of Molecular Imprinting Technology
3.2. Kinetics’ Role in EO Integration in MIP
3.3. Molecularly Imprinted Polymers Applied to the Development of Biosensors for the Detection of EOs
3.4. Nanotechnological Approaches for the Preparation of Molecularly Imprinted Polymers
4. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Structures Used for the Formation of Nanoparticles (NPs) | Description of Major Achievements |
---|---|
Polymeric | Widely used for the extraction and pre-concentration of both small and macromolecules from complex samples, e.g., tramadol and haloperidol [97,98]. |
Silica | A novel synthesis strategy using silica particles and controlled PEG addition which significantly reduced non-specific binding sites and improved MIP selectivity for lysozyme, increasing the imprinting factor from 2.1 to 9.1. This approach, which employed hydrophilic silica nanocores and click chemistry for AFCTP, was also applied to imprinted bovine hemoglobin, demonstrating its general applicability [99]. |
Carbon | Graphene oxide was used to synthesize a double-sided magnetic(M) MIP for the selective recognition of microcystins, incorporating Fe3O4 NPs coated with diphenylethene and acrylamide MIP, anchored to both sides of the GO sheets. This material enabled a magnetic solid-phase extraction procedure with an enrichment factor of 2000, limiting the quantification from 0.1 to 2.0 ng·L−1, and with recoveries of 84% to 98%, showing superior analytical performance and the potential for environmental microcystin removal [100]. |
Gold | The MIPs with AuNPs were developed for the selective detection of dimetridazole. The AuNPs were synthesized by reducing HAuCl4 and were coated with 3-propyl-1-vinylimidazolium bromide, an ionic liquid used as a monomer for MIP synthesis. These imprinted AuNPs were then applied to modified glassy carbon electrodes, resulting in a sensor with a detection limit of 5.0 × 10−10 mol·L−1 for dimetridazole, successfully tested on food samples [101]. |
Magnetic | A novel strategy for extracting and pre-concentrating bisphenol A from milk using a MIP with MNPs’ core synthesized through reversible addition-fragmentation chain transfer polymerization was reported. The MIP, containing β-cyclodextrin and 4-vinyl pyridine as functional monomers and bisphenol A as the template, achieved highly selective cavities, superior selectivity, a detection limit of 3.7 µg·L−1, and high recovery rates of 97% to 99% [102]. |
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Kaspute, G.; Ramanavicius, A.; Prentice, U. Molecular Imprinting Technology for Advanced Delivery of Essential Oils. Polymers 2024, 16, 2441. https://doi.org/10.3390/polym16172441
Kaspute G, Ramanavicius A, Prentice U. Molecular Imprinting Technology for Advanced Delivery of Essential Oils. Polymers. 2024; 16(17):2441. https://doi.org/10.3390/polym16172441
Chicago/Turabian StyleKaspute, Greta, Arunas Ramanavicius, and Urte Prentice. 2024. "Molecular Imprinting Technology for Advanced Delivery of Essential Oils" Polymers 16, no. 17: 2441. https://doi.org/10.3390/polym16172441