Chemical and Biological Investigation on the Potential Ornamental Plant Ophiorrhiza chinensis
Abstract
:1. Introduction
2. Materials and Methods
2.1. General Experimental Procedures
2.2. Plant Material
2.3. Extraction and Isolation
2.4. Characteristic 1H and 13C NMR Spectral Data of Isolates
2.5. In Vitro Tyrosinase Inhibitory Activity Assay
2.6. Molecular Docking Calculations
3. Results and Discussion
3.1. Structure Elucidation of the Isolates
3.2. Chemotaxonomic Significance
3.3. Tyrosinase Inhibitory Bioassay
3.4. Preliminary Analysis of Structure–Activity Relationships for Tyrosinase Inhibition
3.5. Molecular Docking Study
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Compounds | Structural Types | Names | References |
---|---|---|---|
1 | ursane-type triterpene | ursolic acid | [19] |
2 | oleane-type triterpene | 24-acetoxy-3α-hydroxyolean-12-en-28-oic | [20,21] |
3 | stigmastane-type steroid | stigmast-4-ene-3β,6β-diol | [22] |
4 | stigmastane-type steroid | β-stiosterol | [23] |
5 | anthraquinone | anthragallol 1,3-dimethyl ether | [24,25] |
6 | anthraquinone | anthragallol 1,2-dimethyl ether | [26] |
7 | aromatic alkaloid | harmane | [27] |
8 | coumarin | scopoletin | [28] |
Compounds | IC50 (μM) |
---|---|
1 | 43.8 ± 0.1 |
2 | 25.7 ± 1.3 |
3 | 35.5 ± 2.0 |
4 | 65.8 ± 7.8 |
5 | 68.1 ± 1.4 |
6 | 67.4 ± 4.4 |
1 Vitamin C | 3.6 ± 0.3 |
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Bu, Q.; Ge, Z.-Y.; Liang, L.-F. Chemical and Biological Investigation on the Potential Ornamental Plant Ophiorrhiza chinensis. Agronomy 2024, 14, 1872. https://doi.org/10.3390/agronomy14081872
Bu Q, Ge Z-Y, Liang L-F. Chemical and Biological Investigation on the Potential Ornamental Plant Ophiorrhiza chinensis. Agronomy. 2024; 14(8):1872. https://doi.org/10.3390/agronomy14081872
Chicago/Turabian StyleBu, Qing, Zeng-Yue Ge, and Lin-Fu Liang. 2024. "Chemical and Biological Investigation on the Potential Ornamental Plant Ophiorrhiza chinensis" Agronomy 14, no. 8: 1872. https://doi.org/10.3390/agronomy14081872