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Review
Peer-Review Record

Interleukin-11: A Potential Biomarker and Molecular Therapeutic Target in Non-Small Cell Lung Cancer

Cells 2022, 11(14), 2257; https://doi.org/10.3390/cells11142257
by Jason Hongting Leung 1,*,†, Benjamin Ng 2,3,† and Wei-Wen Lim 2,3,†
Reviewer 1:
Reviewer 2:
Cells 2022, 11(14), 2257; https://doi.org/10.3390/cells11142257
Submission received: 22 June 2022 / Revised: 13 July 2022 / Accepted: 15 July 2022 / Published: 21 July 2022

Round 1

Reviewer 1 Report

Leung et al ‘Interleukin-11: a potential biomarker and molecular therapeutic target in non-small cell lung cancer’

 

An interesting review of IL11 in NSCLC as well as a more broad overview of IL11 in other cancers.

Overall this manuscript is very well written and easy to understand, although there is a tendency to have very long sentences. The manuscript would be improved by editing to remove sentences that run into a 4th line.

 

Minor comments:

Line 18-19 – don’t think you need this sentence (‘several reviews… context of NSCLC’) in the abstract. In the intro is fine.

Line 43-47 – consider making this into multiple sentences, it is a bit long at the moment.

Line 47-50 – this sentence is also a bit confusing -consider 2 sentences and expanding on eg. how predictive biomarkers assist decision making. Do the biomarkers indicate prognosis – ie can identify early vs late disease?

Line 56 – what country?

Line 113 – stromal cells from what tissue?

 

Line 276 – should the word ‘only’ be removed? Found in half of pleural effusions but not detected in peripheral blood?

Author Response

Please see the attachment

Author Response File: Author Response.pdf

Reviewer 2 Report

Dear Authors,

the manuscript sounds interesting and good. Please check English language to revise, and please add more to Conclusion.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

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